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Medications for Seizures

The medications listed below are related to or used in the treatment of this condition.

Drug name Rating Reviews Activity ? Rx/OTC Pregnancy CSA Alcohol
Keppra 5.7 189 reviews for Keppra to treat Seizures Rx C N X
Generic name:
levetiracetam systemic
Drug class:
pyrrolidine anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
levetiracetam 5.9 243 reviews for levetiracetam to treat Seizures Rx C N X
Generic name:
levetiracetam systemic
Brand names:
Keppra, Keppra XR, Elepsia XR, Roweepra, Spritam, Roweepra XR
Drug class:
pyrrolidine anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Xcopri 8.6 35 reviews for Xcopri to treat Seizures Rx 5 X
Generic name:
cenobamate systemic
Drug class:
carbamate anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Vimpat 6.7 138 reviews for Vimpat to treat Seizures Rx C 5 X
Generic name:
lacosamide systemic
Drug class:
miscellaneous anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Dilantin 7.3 41 reviews for Dilantin to treat Seizures Rx D N X
Generic name:
phenytoin systemic
Drug class:
hydantoin anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
cenobamate 8.3 43 reviews for cenobamate to treat Seizures Rx 5 X
Generic name:
cenobamate systemic
Brand name:
Xcopri
Drug class:
carbamate anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
phenobarbital 9.2 25 reviews for phenobarbital to treat Seizures Rx D 4 X
Generic name:
phenobarbital systemic
Brand name:
Sezaby
Drug class:
barbiturates, barbiturate anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
zonisamide 5.4 87 reviews for zonisamide to treat Seizures Rx C N X
Generic name:
zonisamide systemic
Brand names:
Zonegran, Zonisade
Drug class:
carbonic anhydrase inhibitor anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Trileptal 7.4 22 reviews for Trileptal to treat Seizures Rx C N X
Generic name:
oxcarbazepine systemic
Drug class:
dibenzazepine anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
diazepam 9.2 17 reviews for diazepam to treat Seizures Rx D 4 X
Generic name:
diazepam systemic
Brand names:
Valium, Diastat, Diastat AcuDial, Diazepam Intensol, Valtoco, Diastat Pediatric, Libervant
Drug class:
benzodiazepines, benzodiazepine anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
oxcarbazepine 7.7 38 reviews for oxcarbazepine to treat Seizures Rx C N X
Generic name:
oxcarbazepine systemic
Brand names:
Trileptal, Oxtellar XR
Drug class:
dibenzazepine anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
phenytoin 7.4 57 reviews for phenytoin to treat Seizures Rx D N X
Generic name:
phenytoin systemic
Brand names:
Dilantin, Phenytoin Sodium, Phenytek
Drug class:
hydantoin anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
topiramate 6.2 22 reviews for topiramate to treat Seizures Rx D N X
Generic name:
topiramate systemic
Brand names:
Topamax, Trokendi XR, Qudexy XR, Eprontia
Drug class:
carbonic anhydrase inhibitor anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Zonegran 6.2 42 reviews for Zonegran to treat Seizures Rx C N X
Generic name:
zonisamide systemic
Drug class:
carbonic anhydrase inhibitor anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Keppra XR 7.1 9 reviews for Keppra XR to treat Seizures Rx C N X
Generic name:
levetiracetam systemic
Drug class:
pyrrolidine anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
lacosamide 6.7 151 reviews for lacosamide to treat Seizures Rx C 5 X
Generic name:
lacosamide systemic
Brand names:
Vimpat, Motpoly XR
Drug class:
miscellaneous anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Topamax 5.1 8 reviews for Topamax to treat Seizures Rx D N X
Generic name:
topiramate systemic
Drug class:
carbonic anhydrase inhibitor anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
valproic acid 7.8 4 reviews for valproic acid to treat Seizures Rx D N X
Generic name:
valproic acid systemic
Brand name:
Valproate Sodium
Drug class:
fatty acid derivative anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
gabapentin Rate Add review Rx C N X
Generic name:
gabapentin systemic
Drug class:
gamma-aminobutyric acid analogs
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Valium 9.8 5 reviews for Valium to treat Seizures Rx D 4 X
Generic name:
diazepam systemic
Drug class:
benzodiazepines, benzodiazepine anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Aptiom 6.8 26 reviews for Aptiom to treat Seizures Rx C N X
Generic name:
eslicarbazepine systemic
Drug class:
dibenzazepine anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Diastat 7.5 2 reviews for Diastat to treat Seizures Rx D 4 X
Generic name:
diazepam systemic
Drug class:
benzodiazepine anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
primidone 8.3 11 reviews for primidone to treat Seizures Rx N N X
Generic name:
primidone systemic
Brand name:
Mysoline
Drug class:
barbiturate anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Mysoline 9.2 5 reviews for Mysoline to treat Seizures Rx N N X
Generic name:
primidone systemic
Drug class:
barbiturate anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Briviact 6.9 22 reviews for Briviact to treat Seizures Rx C 5 X
Generic name:
brivaracetam systemic
Drug class:
pyrrolidine anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Gabitril 5.0 4 reviews for Gabitril to treat Seizures Rx C N X
Generic name:
tiagabine systemic
Drug class:
gamma-aminobutyric acid reuptake inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Oxtellar XR 10 3 reviews for Oxtellar XR to treat Seizures Rx C N X
Generic name:
oxcarbazepine systemic
Drug class:
dibenzazepine anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Phenytoin Sodium Rate Add review Rx D N X
Generic name:
phenytoin systemic
Drug class:
hydantoin anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Vitamin B6 Rate Add review Rx/OTC C N
Generic name:
pyridoxine systemic
Drug class:
vitamins
For consumers:
dosage, interactions, side effects
clonazepam Rate Add review Rx D 4 X
Generic name:
clonazepam systemic
Drug class:
benzodiazepines, benzodiazepine anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Diastat AcuDial 7.5 2 reviews for Diastat AcuDial to treat Seizures Rx D 4 X
Generic name:
diazepam systemic
Drug class:
benzodiazepine anticonvulsants
For consumers:
dosage, interactions, side effects
ethosuximide 7.7 12 reviews for ethosuximide to treat Seizures Rx N N X
Generic name:
ethosuximide systemic
Drug class:
succinimide anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
lamotrigine Rate Add review Rx C N X
Generic name:
lamotrigine systemic
Drug class:
triazine anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Nayzilam 9.7 7 reviews for Nayzilam to treat Seizures Rx D 4 X
Generic name:
midazolam systemic
Drug class:
benzodiazepines
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Trokendi XR Rate Add review Rx D N X
Generic name:
topiramate systemic
Drug class:
carbonic anhydrase inhibitor anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
carbamazepine Rate Add review Rx D N X
Generic name:
carbamazepine systemic
Drug class:
dibenzazepine anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Depakote 9.0 2 reviews for Depakote to treat Seizures Rx D N X
Generic name:
divalproex sodium systemic
Drug class:
fatty acid derivative anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Diazepam Intensol Rate Add review Rx D 4 X
Generic name:
diazepam systemic
Drug class:
benzodiazepines, benzodiazepine anticonvulsants
For consumers:
dosage, interactions, side effects
divalproex sodium 9.0 2 reviews for divalproex sodium to treat Seizures Rx D N X
Generic name:
divalproex sodium systemic
Brand names:
Depakote, Depakote ER, Depakote Sprinkles
Drug class:
fatty acid derivative anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Fycompa 5.0 17 reviews for Fycompa to treat Seizures Rx C 3 X
Generic name:
perampanel systemic
Drug class:
AMPA receptor antagonists
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
midazolam 9.8 8 reviews for midazolam to treat Seizures Rx D 4 X
Generic name:
midazolam systemic
Brand name:
Nayzilam
Drug class:
benzodiazepines
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Valtoco Rate Add review Rx D 4 X
Generic name:
diazepam systemic
Drug class:
benzodiazepine anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
brivaracetam 6.6 26 reviews for brivaracetam to treat Seizures Rx C 5 X
Generic name:
brivaracetam systemic
Brand name:
Briviact
Drug class:
pyrrolidine anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
Depakote ER Rate Add review Rx D N X
Generic name:
divalproex sodium systemic
Drug class:
fatty acid derivative anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Diastat Pediatric Rate Add review Rx D 4 X
Generic name:
diazepam systemic
Drug class:
benzodiazepine anticonvulsants
For consumers:
dosage, interactions, side effects
Elepsia XR Rate Add review Rx C N X
Generic name:
levetiracetam systemic
Drug class:
pyrrolidine anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Phenytek 9.5 2 reviews for Phenytek to treat Seizures Rx D N X
Generic name:
phenytoin systemic
Drug class:
hydantoin anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
pregabalin Rate Add review Rx C 5 X
Generic name:
pregabalin systemic
Drug class:
gamma-aminobutyric acid analogs
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
progesterone Off-label 10 1 review for progesterone to treat Seizures Rx/OTC B N
Generic name:
progesterone systemic
Drug class:
progestins
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Natural Product Monographs, Prescribing Information
Off-label:
Yes
pyridoxine Rate Add review Rx/OTC C N
Generic name:
pyridoxine systemic
Brand names:
Vitamin B6, Aminoxin
Drug class:
vitamins
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Qudexy XR 6.0 2 reviews for Qudexy XR to treat Seizures Rx D N X
Generic name:
topiramate systemic
Drug class:
carbonic anhydrase inhibitor anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Roweepra Rate Add review Rx C N X
Generic name:
levetiracetam systemic
Drug class:
pyrrolidine anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Sabril 9.0 1 review for Sabril to treat Seizures Rx C N X
Generic name:
vigabatrin systemic
Drug class:
gamma-aminobutyric acid analogs
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Spritam Rate Add review Rx C N X
Generic name:
levetiracetam systemic
Drug class:
pyrrolidine anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Aminoxin Rate Add review Rx/OTC C N
Generic name:
pyridoxine systemic
Drug class:
vitamins
For consumers:
dosage, interactions, side effects
Celontin Rate Add review Rx N N X
Generic name:
methsuximide systemic
Drug class:
succinimide anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
clobazam 8.0 1 review for clobazam to treat Seizures Rx C 4 X
Generic name:
clobazam systemic
Drug class:
benzodiazepines, benzodiazepine anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Depakote Sprinkles Rate Add review Rx D N X
Generic name:
divalproex sodium systemic
Drug class:
fatty acid derivative anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Eprontia Rate Add review Rx D N X
Generic name:
topiramate systemic
Drug class:
carbonic anhydrase inhibitor anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
eslicarbazepine 6.7 27 reviews for eslicarbazepine to treat Seizures Rx C N X
Generic name:
eslicarbazepine systemic
Brand name:
Aptiom
Drug class:
dibenzazepine anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Libervant Rate Add review Rx D 4 X
Generic name:
diazepam systemic
Drug class:
benzodiazepine anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
methsuximide Rate Add review Rx N N X
Generic name:
methsuximide systemic
Brand name:
Celontin
Drug class:
succinimide anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
perampanel 5.0 17 reviews for perampanel to treat Seizures Rx C 3 X
Generic name:
perampanel systemic
Brand name:
Fycompa
Drug class:
AMPA receptor antagonists
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
Roweepra XR Rate Add review Rx C N X
Generic name:
levetiracetam systemic
Drug class:
pyrrolidine anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
tiagabine 5.0 4 reviews for tiagabine to treat Seizures Rx C N X
Generic name:
tiagabine systemic
Brand name:
Gabitril
Drug class:
gamma-aminobutyric acid reuptake inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
vigabatrin 9.0 1 review for vigabatrin to treat Seizures Rx C N X
Generic name:
vigabatrin systemic
Brand names:
Sabril, Vigadrone, Vigpoder
Drug class:
gamma-aminobutyric acid analogs
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Zonisade Rate Add review Rx C N X
Generic name:
zonisamide systemic
Drug class:
carbonic anhydrase inhibitor anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
acetazolamide Rate Add review Rx C N
Generic name:
acetazolamide systemic
Drug class:
carbonic anhydrase inhibitors, carbonic anhydrase inhibitor anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
clorazepate Rate Add review Rx N 4 X
Generic name:
clorazepate systemic
Drug class:
benzodiazepines
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
corticotropin Off-label Rate Add review Rx C N
Generic name:
corticotropin systemic
Brand name:
H.P. Acthar Gel
Drug class:
corticotropin
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
Off-label:
Yes
felbamate Rate Add review Rx C N X
Generic name:
felbamate systemic
Drug class:
carbamate anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
ganaxolone Rate Add review Rx 5 X
Generic name:
ganaxolone systemic
Brand name:
Ztalmy
Drug class:
gamma-aminobutyric acid analogs
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
H.P. Acthar Gel Off-label Rate Add review Rx C N
Generic name:
corticotropin systemic
Drug class:
corticotropin
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Off-label:
Yes
Motpoly XR Rate Add review Rx C 5 X
Generic name:
lacosamide systemic
Drug class:
miscellaneous anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
rufinamide Rate Add review Rx C N X
Generic name:
rufinamide systemic
Drug class:
dibenzazepine anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Sezaby Rate Add review Rx D 4 X
Generic name:
phenobarbital systemic
Drug class:
barbiturates, barbiturate anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Valproate Sodium Rate Add review Rx D N X
Generic name:
valproic acid systemic
For consumers:
dosage, interactions, side effects
Vigadrone Rate Add review Rx C N X
Generic name:
vigabatrin systemic
Drug class:
gamma-aminobutyric acid analogs
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Vigpoder Rate Add review Rx C N X
Generic name:
vigabatrin systemic
Drug class:
gamma-aminobutyric acid analogs
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Ztalmy Rate Add review Rx 5 X
Generic name:
ganaxolone systemic
Drug class:
gamma-aminobutyric acid analogs
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information

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Frequently asked questions

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Topics under Seizures

Legend

Rating For ratings, users were asked how effective they found the medicine while considering positive/adverse effects and ease of use (1 = not effective, 10 = most effective).
Activity Activity is based on recent site visitor activity relative to other medications in the list.
Rx Prescription only.
OTC Over-the-counter.
Rx/OTC Prescription or Over-the-counter.
Off-label This medication may not be approved by the FDA for the treatment of this condition.
EUA An Emergency Use Authorization (EUA) allows the FDA to authorize unapproved medical products or unapproved uses of approved medical products to be used in a declared public health emergency when there are no adequate, approved, and available alternatives.
Expanded Access Expanded Access is a potential pathway for a patient with a serious or immediately life-threatening disease or condition to gain access to an investigational medical product (drug, biologic, or medical device) for treatment outside of clinical trials when no comparable or satisfactory alternative therapy options are available.
Pregnancy Category
A Adequate and well-controlled studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).
B Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
C Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
D There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
X Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use in pregnant women clearly outweigh potential benefits.
N FDA has not classified the drug.
Controlled Substances Act (CSA) Schedule
M The drug has multiple schedules. The schedule may depend on the exact dosage form or strength of the medication.
U CSA Schedule is unknown.
N Is not subject to the Controlled Substances Act.
1 Has a high potential for abuse. Has no currently accepted medical use in treatment in the United States. There is a lack of accepted safety for use under medical supervision.
2 Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence.
3 Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence.
4 Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3.
5 Has a low potential for abuse relative to those in schedule 4. Has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 4.
Alcohol
X Interacts with Alcohol.

Further information

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