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Phenytoin Sodium (phenytoin) Drug Interactions

A total of 1272 drugs are known to interact with Phenytoin Sodium (phenytoin).

  • 214 major drug interactions
  • 990 moderate drug interactions
  • 68 minor drug interactions

Show all medications in the database that may interact with Phenytoin Sodium (phenytoin).

Check for interactions

Type in a drug name to check for interactions with Phenytoin Sodium (phenytoin).

Most frequently checked interactions

View interaction reports for Phenytoin Sodium (phenytoin) and the medicines listed below.

  • amlodipine (Norvasc)
  • aspirin (Aspir 81, Ecotrin, Acetylsalicylic Acid, Aspirin Low Strength, Bayer Aspirin, Aspir-Low, Ascriptin, Bufferin, Fasprin, Arthritis Pain, Easprin, Aspergum, Aspiritab, Halfprin, Empirin, Ascriptin Enteric, Aspirin Lite Coat, Aspi-Cor, Aspirtab, Ecotrin Adult Low Strength, Bayer Children's Aspirin, Buffered Aspirin, Durlaza, Entercote, St. Joseph Aspirin, Acuprin 81, St. Joseph 81 mg Aspirin Enteric Safety-Coated, Migralex, Ascriptin Maximum Strength, Arthritis Foundation Pain Reliever, Bayer Aspirin with Heart Advantage, Bufferin Low Dose, Medi-Seltzer, Sloprin, St. Joseph 81 mg Chewable Aspirin, ZORprin, Low Dose ASA, Bayer Aspirin Extra Strength Plus, Buffex, Ecotrin Maximum Strength, Extra Strength Bayer, Genacote, Gennin-FC, Genprin, Litecoat Aspirin, Minitabs, Tri-Buffered Aspirin, Entaprin, Bufferin Arthritis Strength, Bufferin Extra Strength, Therapy Bayer, Stanback Analgesic, Norwich Aspirin, Ecpirin, Bayer Women's Aspirin With Calcium, Zero-Order Release, YSP Aspirin, Miniprin, Bayer Aspirin Regimen, Heartline, Bayer Advanced Aspirin, Buffasal)
  • atenolol (Tenormin)
  • atorvastatin (Lipitor)
  • clopidogrel (Plavix)
  • diazepam (Valium, Diastat, Diazepam Intensol, Diastat AcuDial, Valrelease, Zetran, Diastat Pediatric, Dizac)
  • folic acid (Folvite, Folacin-800, FA-8, FaLessa)
  • furosemide (Lasix, Diaqua-2, Lo-Aqua)
  • gabapentin (Neurontin, Gralise, Gabarone, Fanatrex)
  • Keppra (levetiracetam)
  • levetiracetam (Keppra, Keppra XR, Roweepra, Spritam, Elepsia XR, Roweepra XR)
  • lisinopril (Zestril, Prinivil, Qbrelis)
  • lorazepam (Ativan, Lorazepam Intensol)
  • metformin (Glucophage, Glumetza, Glucophage XR, Fortamet, Riomet)
  • omeprazole (Prilosec, Prilosec OTC, Zegerid (Original Formulation), Omesec)
  • oxcarbazepine (Trileptal, Oxtellar XR)
  • pantoprazole (Protonix, Protonix IV)
  • Paracetamol (acetaminophen)
  • phenobarbital (Luminal, Solfoton)
  • ranitidine (Zantac, Zantac 150, Zantac 75, Zantac 300, Acid Reducer, Zantac 150 EFFERdose, Taladine, Zantac 25 mg EFFERdose, Berkley and Jensen Acid Reducer Maximum Strength, Deprizine, Zantac GELdose, Zantac 300 GELdose, Zantac EFFERdose, Acid Reducer Non-Prescription Strength, Zantac Injection, Acid Relief, Sunmark Acid Reducer Maximum Strength, Acid Control 75, Careone Acid Reducer, Equaline Heartburn Relief, Acid Control 150)
  • simvastatin (Zocor, FloLipid)
  • Vitamin D3 (cholecalciferol)

Phenytoin Sodium (phenytoin) alcohol/food interactions

There is 1 alcohol/food interaction with Phenytoin Sodium (phenytoin)

Phenytoin Sodium (phenytoin) disease interactions

There are 12 disease interactions with Phenytoin Sodium (phenytoin) which include:

Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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