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Move to Zero-Emission Trucks Could Save 66,000 U.S. Lives

Replacing diesel-powered trucks with electric vehicles would save tens of thousands of U.S. lives, a new American Lung Association report says. The benefit...

U.S. Gun Deaths Reach New Highs

Murders and suicides involving guns have reached an all-time high in the United States, health officials reported Thursday. From 2020 to 2021, the rate...

Provention Bio to Combine Forces with Sanofi to Support Potential U.S. Launch of Teplizumab for Delay in Onset of Clinical Type 1 Diabetes (T1D) in At-Risk Individuals

Provention receives $20 million nonrefundable payment granting Sanofi exclusive right of first negotiation to in-license teplizumab globally for T1D U.S....

Biogen and Denali Therapeutics Announce Initiation of the Phase 3 LIGHTHOUSE Study in Parkinson’s Disease Associated with LRRK2 Pathogenic Mutations

Global Phase 3 study to evaluate efficacy and safety of BIIB122, a small molecule inhibitor of LRRK2 LRRK2 mutations are one of the most common genetic...

Lilly Receives U.S. FDA Fast Track Designation for Tirzepatide for the Treatment of Adults with Obesity, or Overweight with Weight-Related Comorbidities

The Fast Track designation accelerates tirzepatide's path to U.S. FDA submission for the treatment of adults with obesity, or overweight with weight-related...

Findings Suggest COVID-19 Rebound Not Caused by Impaired Immune Response

Detailed analysis of eight patients published. October 6, 2022 -- Findings from a small study of eight patients published in Clinical Infectious Diseases...

COVID-19 Boosters Could Save 90,000 Lives This Winter

The number Americans who will die of COVID-19 this winter could depend on how many get their booster shots, a new report shows. Up to 90,000 U.S. COVID-19...

Most Safety Signals Reported to FDA Lead to Regulatory Action

Most potential safety signals identified from the U.S. Food and Drug Administration Adverse Event Reporting System (FAERS) led to FDA regulatory action,...

Incidence of Infections Caused by Salmonella Reduced in 2021

During 2021, there was a decrease in the incidence of infections caused by Salmonella and an increase in incidence of infections caused by Cyclospora,...

Change Seen in Pediatric Respiratory Infection Trends After SARS-CoV-2 Emergence

Seasonal trends in acute respiratory illnesses (ARIs) changed after emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), according...

AI Could Improve Diagnostic Accuracy of Breast DCE-MRI

A deep learning (DL) system could improve the diagnostic accuracy of dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) of breast tissue for...

SARS-CoV-2 May Not Cause Increase in Type 1 Diabetes in Children

The increase in incidence of type 1 diabetes among children during the pandemic may not have been caused by severe acute respiratory syndrome coronavirus...

Sacral Neuromodulation Safe for Lower Urinary Tract Dysfunction

Sacral neuromodulation (SNM) is safe for patients with refractory lower urinary tract dysfunction and yields high patient satisfaction, according to a...

Telmisartan Does Not Improve 6-Minute Walk Distance in PAD

For patients with lower-extremity peripheral artery disease (PAD), telmisartan does not improve 6-minute walk distance compared with placebo at six-month...

Pollution Tied to Risk for Serious COVID-19 Despite Vaccination

Regardless of vaccination status, exposure to air pollution is associated with an increased risk for COVID-19 hospitalization, according to a letter to...

Incidence of Diabetes Increased for Youth With Down Syndrome

The incidence of diabetes is higher in children and young adults with Down syndrome (DS) compared with the general population, according to a study published...

Combined Oral Contraceptives Do Not Seem to Worsen Macromastia

Use of a combined oral contraceptive pill during adolescence may be associated with less severe breast hypertrophy and does not seem to exacerbate macromastia-related...

Patient Belief About Success of Antibiotics Tied to Appendicitis Outcomes

Positive patient beliefs about the likely success of antibiotics for appendicitis are associated with a lower risk for appendectomy, according to research...

Breast Cancer Recurrence Rates Low With Nipple-Sparing Mastectomy

For patients undergoing nipple-sparing mastectomy, overall breast cancer recurrence rates are low at a median follow-up of 10 years, according to a study...

Oxygen Delivery Device-Related Pressure Injuries Can Be Prevented

A quality improvement project can result in fewer medical device-related pressure injuries attributed to oxygen delivery devices, according to a study...

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Recently added consumer and prescribing information: Skysona, Rolvedon, Sotyktu, Daxxify, Spevigo, Auvelity, Zynteglo, Voquezna Triple Pak, Cimerli, Kyzatrex

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Latest FDA New Drug Approvals

  • Lytgobi Lytgobi (futibatinib) is an irreversible tyrosine kinase inhibitor of FGFR1, 2, 3 and 4 for the treatment of intrahepatic...
  • Relyvrio Relyvrio (sodium phenylbutyrate and taurursodiol) is a neuroprotective therapy for the treatment of amyotrophic lateral sclerosis (ALS).
  • Vegzelma Vegzelma (bevacizumab-adcd) is a vascular endothelial growth factor (VEGF) inhibitor biosimilar to Avastin (bevacizumab) for the treatment...

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Drugs in Development (Not yet approved)

  • Lumryz Lumryz (sodium oxybate) is a once-nightly formulation of the approved central nervous system depressant sodium oxybate in development for...
  • Libervant Libervant (diazepam) is a buccal film formulation of the approved benzodiazepine diazepam in development for the management of seizure clusters.

More drugs in development