Gut Microbiota Composition Differs for Those With, Without Gestational Diabetes
By Lori Solomon HealthDay Reporter
TUESDAY, July 8, 2025 -- Fecal microbiota analysis of pregnant women may provide early identification of those at risk for gestational diabetes, according to a study published online July 1 in Microbiology Spectrum.
Weirong Yao, from the Second Hospital of Zhangzhou in China, and colleagues analyzed the fecal microbiota of 61 pregnant women during the first trimester using 16S rRNA sequencing.
The researchers found that microbial profiles were correlated with oral glucose tolerance test results at 24 to 28 weeks of gestation and clinical delivery outcomes. Significant differences in gut microbiota composition between gestational diabetes mellitus and healthy pregnancies were seen for both the phylum and genus levels. An early diagnostic model based on genus-level markers achieved an area under the curve of 98.23, indicating high diagnostic precision.
"These findings suggest that microbiota-based tools could enable early, noninvasive detection of gestational diabetes mellitus, offering new opportunities for prevention and personalized management," the authors write. "This research highlights the role of the gut microbiome in pregnancy and has important implications for improving maternal and fetal health outcomes."
Disclaimer: Statistical data in medical articles provide general trends and do not pertain to individuals. Individual factors can vary greatly. Always seek personalized medical advice for individual healthcare decisions.
© 2025 HealthDay. All rights reserved.
Posted July 2025
Read this next
Older Age, Lower Fitness Linked to Atrial Ectopic Burden
FRIDAY, Aug. 29, 2025 -- Age is a significant independent risk factor for atrial ectopic burden (AEB) and ventricular ectopic burden (VEB), according to a study presented at the...
Geriatric Assessment in the Emergency Department Reduces Admission Rates
FRIDAY, Aug. 29, 2025 -- A comprehensive assessment of older adults being seen in the emergency department can help reduce hospital admissions, according to a study published...
2010 to 2023 Saw Decline in Births, Increase in Deaths in the United States
FRIDAY, Aug. 29, 2025 -- From 2010 to 2023, the number of births in the United States declined, and the number of deaths increased, according to the Aug. 27 National Vital...
More news resources
- FDA Medwatch Drug Alerts
- Daily MedNews
- News for Health Professionals
- New Drug Approvals
- New Drug Applications
- Drug Shortages
- Clinical Trial Results
- Generic Drug Approvals
Subscribe to our newsletter
Whatever your topic of interest, subscribe to our newsletters to get the best of Drugs.com in your inbox.