Generic Name: empagliflozin (EM pa gli FLOE zin)
Brand Names: Jardiance
What is Jardiance?
Jardiance (empagliflozin) is an oral diabetes medicine that helps control blood sugar levels. Empagliflozin works by helping the kidneys get rid of glucose from your bloodstream.
Jardiance is used together with diet and exercise to improve blood sugar control in adults with type 2 diabetes mellitus.
Jardiance is also used to lower the risk of death from heart attack, stroke, or heart failure in adults with type 2 diabetes who also have heart disease.
Jardiance is not for treating type 1 diabetes.
You should not use Jardiance if you have severe kidney disease, if you are on dialysis, or if you are in a state of diabetic ketoacidosis (call your doctor for treatment with insulin). Jardiance is not for treating type 1 diabetes.
Before taking this medicine
You should not use Jardiance if you are allergic to empagliflozin, or if you have:
kidney disease (or if you are on dialysis); or
if you are in a state of diabetic ketoacidosis (call your doctor for treatment with insulin).
To make sure Jardiance is safe for you, tell your doctor if you have:
congestive heart failure;
low blood pressure;
high cholesterol levels;
a history of bladder infections;
if you are on a low salt diet; or
if you are 65 or older.
It is not known whether Jardiance will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medicine.
It is not known whether empagliflozin passes into breast milk or if it could harm a nursing baby. You should not breast-feed while using Jardiance.
How should I take Jardiance?
Jardiance is usually taken once per day in the morning. Follow all directions on your prescription label. Your doctor may occasionally change your dose to make sure you get the best results. Do not take this medicine in larger or smaller amounts or for longer than recommended.
You may take Jardiance with or without food, but take it the same way each time.
You may have very low blood pressure while taking this medication. Call your doctor if you are sick with vomiting or diarrhea, or if you are sweating more than usual.
Your blood sugar will need to be checked often, and you may also need to test the level of ketones your urine. Jardiance can cause life- threatening ketoacidosis (too much acid in the blood). Even if your blood sugar is normal, contact your doctor if a urine test shows that you have ketones in the urine.
Low blood sugar (hypoglycemia) can happen to everyone who has diabetes. Symptoms include headache, hunger, sweating, irritability, dizziness, nausea, fast heart rate, and feeling anxious or shaky. To quickly treat low blood sugar, always keep a fast-acting source of sugar with you such as fruit juice, hard candy, crackers, raisins, or non-diet soda.
Your doctor can prescribe a glucagon emergency injection kit to use in case you have severe hypoglycemia and cannot eat or drink. Be sure your family and close friends know how to give you this injection in an emergency.
Also watch for signs of high blood sugar (hyperglycemia) such as increased thirst or urination, blurred vision, headache, and tiredness.
Blood sugar levels can be affected by stress, illness, surgery, exercise, alcohol use, or skipping meals. Ask your doctor before changing your dose or medication schedule.
This medicine can cause positive results with certain lab tests for glucose (sugar) in the urine. Tell any doctor who treats you that you are using Jardiance.
Jardiance is only part of a treatment program that may also include diet, exercise, weight control, blood sugar testing, and special medical care. Follow your doctor's instructions very closely.
Store at room temperature away from moisture and heat.
Jardiance dosing information
Usual Adult Dose for Diabetes Type 2:
Initial dose: 10 mg orally once in the morning
Maximum dose: 25 mg orally once in the morning
-Limitation of use: Should not be used in Type 1 diabetes mellitus or diabetic ketoacidosis
-Take with or without food
Use: An adjunct to diet and exercise to improve glycemic control in adults with Type 2 diabetes mellitus
What other drugs will affect Jardiance?
See also: Dosage Information (in more detail)
What happens if I miss a dose?
Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
What should I avoid while taking Jardiance?
Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Get up slowly and steady yourself to prevent a fall.
Jardiance side effects
Get emergency medical help if you have any signs of an allergic reaction to Jardiance: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have:
a light-headed feeling, like you might pass out;
frequent urge to urinate;
swelling, rapid weight gain, little or no urinating;
dehydration symptoms--feeling very thirsty or hot, being unable to urinate, heavy sweating, or hot and dry skin;
ketoacidosis (too much acid in the blood) - nausea, vomiting, stomach pain, confusion, unusual drowsiness, or trouble breathing:
signs of a bladder infection--pain or burning when you urinate, urine that looks cloudy, pain in pelvis or back; or
signs of a genital infection (penis or vagina)--pain, burning, itching, rash, redness, odor, or discharge.
Older adults may be more likely to have side effects from this medicine.
Common Jardiance side effects may include:
bladder infection; or
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
See also: Side effects (in more detail)
What other drugs will affect Jardiance?
Tell your doctor about all medicines you use, and those you start or stop using during your treatment with Jardiance, especially:
blood pressure medicine;
a diuretic or "water pill";
insulin or other oral diabetes medications; or
NSAIDs (nonsteroidal anti-inflammatory drugs)- aspirin, ibuprofen (Advil, Motrin), naproxen (Aleve), celecoxib, diclofenac, indomethacin, meloxicam, and others.
This list is not complete. Other drugs may interact with empagliflozin, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.
More about Jardiance (empagliflozin)
- Side Effects
- During Pregnancy
- Dosage Information
- Drug Images
- Drug Interactions
- Support Group
- Pricing & Coupons
- En Español
- 36 Reviews – Add your own review/rating
- Drug class: SGLT-2 inhibitors
Related treatment guides
Where can I get more information?
- Your pharmacist can provide more information about Jardiance.
- Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use Jardiance only for the indication prescribed.
- Disclaimer: Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
Copyright 1996-2017 Cerner Multum, Inc. Version: 1.04. Revision Date: 2016-12-05, 2:42:46 PM.