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Medications for Diabetes, Type 2

Other names: Diabetes; Noninsulin-dependent Diabetes; Type 2 Diabetes

What is Diabetes, Type 2: Type 2 diabetes is characterized by "insulin resistance" as body cells do not respond appropriately when insulin is present. This is a more complex problem than type 1, but is sometimes easier to treat, since insulin is still produced, especially in the initial years. Type… Read more

See also: sub-topics

Medications to treat Diabetes, Type 2

The following list of medications are in some way related to, or used in the treatment of this condition.

Drug name Rx / OTC Pregnancy CSA Alcohol Reviews Rating Popularity
metformin B N X 139 reviews
6.0

Generic name: metformin systemic

Brand names:  Glucophage, Fortamet, Glucophage XR, Glumetza, Riomet …

Drug class: non-sulfonylureas

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

 
Glucophage B N X 26 reviews
6.0

Generic name: metformin systemic

Drug class: non-sulfonylureas

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

 
Victoza C N X 388 reviews
7.0

Generic name: liraglutide systemic

Drug class: incretin mimetics

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

 
Januvia B N X 63 reviews
6.0

Generic name: sitagliptin systemic

Drug class: dipeptidyl peptidase 4 inhibitors

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

 
Amaryl C N X 15 reviews
8.0

Generic name: glimepiride systemic

Drug class: sulfonylureas

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

 
Actos C N X 33 reviews
5.0

Generic name: pioglitazone systemic

Drug class: thiazolidinediones

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

 
Invokana C N X 209 reviews
6.0

Generic name: canagliflozin systemic

Drug class: SGLT-2 inhibitors

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

 
Levemir B N X 19 reviews
7.0

Generic name: insulin detemir systemic

Drug class: insulin

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

 
Glucotrol C N X 9 reviews
7.0

Generic name: glipizide systemic

Drug class: sulfonylureas

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

 
Lantus C N X 18 reviews
7.0

Generic name: insulin glargine systemic

Drug class: insulin

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

 
glipizide C N X 40 reviews
6.0

Generic name: glipizide systemic

Brand names:  Glucotrol, GlipiZIDE XL, Glucotrol XL

Drug class: sulfonylureas

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

 
Janumet B N X 40 reviews
6.0

Generic name: metformin / sitagliptin systemic

Drug class: antidiabetic combinations

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

 
glimepiride C N X 40 reviews
7.0

Generic name: glimepiride systemic

Brand name:  Amaryl

Drug class: sulfonylureas

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

 
Byetta C N X 78 reviews
8.0

Generic name: exenatide systemic

Drug class: incretin mimetics

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

 
Bydureon C N X 178 reviews
6.0

Generic name: exenatide systemic

Drug class: incretin mimetics

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

 
Farxiga C N X 56 reviews
5.0

Generic name: dapagliflozin systemic

Drug class: SGLT-2 inhibitors

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

 
Humalog B N X 4 reviews
7.0

Generic name: insulin lispro systemic

Drug class: insulin

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

 
Tradjenta B N X 27 reviews
4.0

Generic name: linagliptin systemic

Drug class: dipeptidyl peptidase 4 inhibitors

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

 
Onglyza B N X 13 reviews
6.0

Generic name: saxagliptin systemic

Drug class: dipeptidyl peptidase 4 inhibitors

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

 
Novolog B N X 5 reviews
6.0

Generic name: insulin aspart systemic

Drug class: insulin

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph

 
Lantus Solostar C N X 15 reviews
7.0

Generic name: insulin glargine systemic

Drug class: insulin

For consumers: dosage, interactions, side effects

 
metformin / sitagliptin B N X 47 reviews
6.0

Generic name: metformin / sitagliptin systemic

Brand names:  Janumet, Janumet XR

Drug class: antidiabetic combinations

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts

 
pioglitazone C N X 35 reviews
5.0

Generic name: pioglitazone systemic

Brand name:  Actos

Drug class: thiazolidinediones

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

 
Prandin C N X 5 reviews
9.0

Generic name: repaglinide systemic

Drug class: meglitinides

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

 
GlipiZIDE XL C N X 4 reviews
6.0

Generic name: glipizide systemic

Drug class: sulfonylureas

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

 
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Topics under Diabetes, Type 2

Alternative treatments for Diabetes, Type 2

The following products are considered to be alternative treatments or natural remedies for Diabetes, Type 2. Their efficacy may not have been scientifically tested to the same degree as the drugs listed in the table above. However there may be historical, cultural or anecdotal evidence linking their use to the treatment of Diabetes, Type 2.

Learn more about Diabetes, Type 2

Micromedex® Care Notes

Drugs.com Health Center

Mayo Clinic Reference

Legend

Off Label This medication may not be approved by the FDA for the treatment of this condition.
Prescription Only / Over the Counter
Rx Prescription Only
OTC Over the Counter
Rx/OTC Prescription or Over the Counter
Pregnancy
A Adequate and well-controlled studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).
B Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
C Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
D There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
X Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use in pregnant women clearly outweigh potential benefits.
N FDA has not classified the drug.
Controlled Substances Act Schedule
N Is not subject to the Controlled Substances Act.
1 Has a high potential for abuse. Has no currently accepted medical use in treatment in the United States. There is a lack of accepted safety for use under medical supervision.
2 Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence.
3 Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence.
4 Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3.
5 Has a low potential for abuse relative to those in schedule 4. Has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 4.
Alcohol
X Interacts with Alcohol.

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