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Invokana (canagliflozin) Drug Interactions

A total of 787 drugs are known to interact with Invokana (canagliflozin).

  • 1 major drug interaction
  • 735 moderate drug interactions
  • 51 minor drug interactions

Show all medications in the database that may interact with Invokana (canagliflozin).

Check for interactions with Invokana (canagliflozin)

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Common medications checked in combination with Invokana (canagliflozin)

  • amlodipine (Norvasc)
  • aspirin (Aspir 81, Ecotrin, Acetylsalicylic Acid, Aspirin Low Strength, Bayer Aspirin, Aspir-Low, Ascriptin, Ecotrin Adult Low Strength, Bufferin, Aspiritab, Arthritis Pain, Fasprin, Halfprin, Easprin, Durlaza, Aspirtab, St. Joseph 81 mg Chewable Aspirin, Aspergum, Low Dose ASA, Buffered Aspirin, Ecotrin Maximum Strength, Ascriptin Enteric, Acuprin 81, St. Joseph 81 mg Aspirin Enteric Safety-Coated, Aspirin Lite Coat, Bayer Aspirin Regimen, Aspi-Cor, Empirin, Bayer Children's Aspirin, Bufferin Extra Strength, St. Joseph Aspirin, Bayer Women's Aspirin With Calcium, Miniprin, Migralex, Ascriptin Maximum Strength, Arthritis Foundation Pain Reliever, Bayer Aspirin with Heart Advantage, Bufferin Low Dose, Medi-Seltzer, Sloprin, ZORprin, Bayer Aspirin Extra Strength Plus, Buffex, Entercote, Extra Strength Bayer, Genacote, Gennin-FC, Genprin, Litecoat Aspirin, Minitabs, Tri-Buffered Aspirin, Entaprin, Bufferin Arthritis Strength, Therapy Bayer, Stanback Analgesic, Norwich Aspirin, Ecpirin, Zero-Order Release, YSP Aspirin, Heartline, Bayer Advanced Aspirin, Buffasal)
  • Aspirin Low Strength (aspirin)
  • atorvastatin (Lipitor)
  • Crestor (rosuvastatin)
  • fenofibrate (TriCor, Lofibra, Lipofen, Antara, Triglide, Lipidil EZ, Lipidil Micro, Fenoglide, Lipidil Supra)
  • gabapentin (Neurontin, Gralise, Gabarone, Fanatrex)
  • glimepiride (Amaryl)
  • glipizide (Glucotrol, GlipiZIDE XL, Glucotrol XL)
  • insulin
  • Janumet (metformin / sitagliptin)
  • Januvia (sitagliptin)
  • Jardiance (empagliflozin)
  • Lantus (insulin glargine)
  • levothyroxine (Synthroid, Levoxyl, Tirosint, Levothroid, Eltroxin, Unithroid, Levothyrox, Euthyrox, Levo-T, L Thyroxine Roche, Eutroxsig, Novothyrox, Oroxine, Tirosint-Sol, Levotabs, Levotec, Evotrox)
  • lisinopril (Zestril, Prinivil, Qbrelis)
  • losartan (Cozaar)
  • Lyrica (pregabalin)
  • metformin (Glucophage, Glucophage XR, Glumetza, Riomet, Fortamet)
  • omeprazole (Prilosec, Prilosec OTC, Zegerid (Original Formulation), Omesec)
  • phentermine (Adipex-P, Lomaira, Fastin, Ionamin, Suprenza, Obenix, Atti-Plex P, Pro-Fast HS, Phentercot, Oby-Cap, Phentride, Obephen, Panshape M, Pro-Fast SR, T-Diet, Zantryl, Oby-Trim, Teramine, Pro-Fast SA, Teramine ER)
  • simvastatin (Zocor, FloLipid)
  • Tradjenta (linagliptin)
  • Victoza (liraglutide)
  • Vitamin D3 (cholecalciferol)

Invokana (canagliflozin) alcohol/food interactions

There are 2 alcohol/food interactions with Invokana (canagliflozin)

Invokana (canagliflozin) disease interactions

There are 4 disease interactions with Invokana (canagliflozin) which include:

Drug Interaction Classification

The classifications below are a general guideline only. It is difficult to determine the relevance of a particular drug interaction to any individual given the large number of variables.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No information available.

Do not stop taking any medications without consulting your healthcare provider.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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