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Invokana (canagliflozin) Drug Interactions

A total of 790 drugs are known to interact with Invokana (canagliflozin).

  • 1 major drug interaction
  • 738 moderate drug interactions
  • 51 minor drug interactions

Show all medications in the database that may interact with Invokana (canagliflozin).

Check for interactions

Type in a drug name to check for interactions with Invokana (canagliflozin).

Most frequently checked interactions

View interaction reports for Invokana (canagliflozin) and the medicines listed below.

  • amlodipine (Norvasc)
  • aspirin (Aspir 81, Ecotrin, Acetylsalicylic Acid, Aspirin Low Strength, Bayer Aspirin, Aspir-Low, Arthritis Pain, Bufferin, Ascriptin, Easprin, Fasprin, Aspergum, Empirin, Aspiritab, Bayer Children's Aspirin, Durlaza, Ascriptin Enteric, Entercote, Acuprin 81, Aspirin Lite Coat, Aspi-Cor, Aspirtab, Halfprin, Ecotrin Adult Low Strength, Buffered Aspirin, St. Joseph Aspirin, Ascriptin Maximum Strength, Arthritis Foundation Pain Reliever, Bayer Aspirin with Heart Advantage, Bufferin Low Dose, Medi-Seltzer, Sloprin, St. Joseph 81 mg Chewable Aspirin, ZORprin, Low Dose ASA, Bayer Aspirin Extra Strength Plus, Buffex, Ecotrin Maximum Strength, Extra Strength Bayer, Genacote, Gennin-FC, Genprin, Litecoat Aspirin, Minitabs, Tri-Buffered Aspirin, Entaprin, Bufferin Arthritis Strength, Bufferin Extra Strength, Therapy Bayer, Stanback Analgesic, Norwich Aspirin, St. Joseph 81 mg Aspirin Enteric Safety-Coated, Ecpirin, Bayer Women's Aspirin With Calcium, Zero-Order Release, YSP Aspirin, Miniprin, Bayer Aspirin Regimen, Migralex, Heartline, Bayer Advanced Aspirin, Buffasal)
  • Aspirin Low Strength (aspirin)
  • atorvastatin (Lipitor)
  • Crestor (rosuvastatin)
  • fenofibrate (TriCor, Lofibra, Antara, Lipofen, Triglide, Fenoglide, Lipidil EZ, Lipidil Micro, Lipidil Supra)
  • gabapentin (Neurontin, Gralise, Gabarone, Fanatrex)
  • glimepiride (Amaryl)
  • glipizide (Glucotrol, Glucotrol XL, GlipiZIDE XL)
  • insulin
  • Janumet (metformin / sitagliptin)
  • Januvia (sitagliptin)
  • Jardiance (empagliflozin)
  • Lantus (insulin glargine)
  • levothyroxine (Synthroid, Levoxyl, Tirosint, Levothroid, Eltroxin, Levothyrox, Euthyrox, Unithroid, L Thyroxine Roche, Levo-T, Oroxine, Eutroxsig, Novothyrox, Tirosint-Sol, Levotabs, Levotec, Evotrox)
  • lisinopril (Zestril, Prinivil, Qbrelis)
  • losartan (Cozaar)
  • Lyrica (pregabalin)
  • metformin (Glucophage, Glumetza, Glucophage XR, Fortamet, Riomet)
  • omeprazole (Prilosec, Prilosec OTC, Zegerid (Original Formulation), Omesec)
  • phentermine (Adipex-P, Lomaira, Fastin, Suprenza, Ionamin, Teramine, Obenix, Atti-Plex P, Pro-Fast HS, Phentercot, Oby-Cap, Phentride, Obephen, Panshape M, Pro-Fast SR, T-Diet, Zantryl, Oby-Trim, Pro-Fast SA, Teramine ER)
  • simvastatin (Zocor, FloLipid)
  • Tradjenta (linagliptin)
  • Victoza (liraglutide)
  • Vitamin D3 (cholecalciferol)

Invokana (canagliflozin) alcohol/food interactions

There are 2 alcohol/food interactions with Invokana (canagliflozin)

Invokana (canagliflozin) disease interactions

There are 4 disease interactions with Invokana (canagliflozin) which include:

Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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