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Medications for Cardiovascular Risk Reduction

Cardiovascular disease, or heart disease, is a class of diseases that involve the heart and or its blood vessels. Causes are many with the most common being athersclerosis and hypertension. Cardiovascular disease is the leading cause of death world wide. While it mainly affects older adults early prevention by making lifestyle changes such as diet, exercise and medication have have shown to reduce the risk of complications.

Drugs used to treat Cardiovascular Risk Reduction

The following list of medications are in some way related to or used in the treatment of this condition.

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Drug name Rating Reviews Activity ? Rx/OTC Pregnancy CSA Alcohol
simvastatin 4.8 6 reviews for simvastatin to treat Cardiovascular Risk Reduction
Rx X N X
Generic name:
simvastatin systemic
Brand names:
Zocor, FloLipid
Drug class:
statins
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Ozempic 6.2 197 reviews for Ozempic to treat Cardiovascular Risk Reduction
Rx N X
Generic name:
semaglutide systemic
Drug class:
incretin mimetics
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Repatha 4.2 78 reviews for Repatha to treat Cardiovascular Risk Reduction
Rx N
Generic name:
evolocumab systemic
Drug class:
PCSK9 inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
semaglutide 6.4 205 reviews for semaglutide to treat Cardiovascular Risk Reduction
Rx N X
Generic name:
semaglutide systemic
Brand name:
Ozempic
Drug class:
incretin mimetics
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
evolocumab 4.1 79 reviews for evolocumab to treat Cardiovascular Risk Reduction
Rx N
Generic name:
evolocumab systemic
Brand name:
Repatha
Drug class:
PCSK9 inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
Jardiance 4.7 9 reviews for Jardiance to treat Cardiovascular Risk Reduction
Rx C N X
Generic name:
empagliflozin systemic
Drug class:
SGLT-2 inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
ramipril 6.1 8 reviews for ramipril to treat Cardiovascular Risk Reduction
Rx D N X
Generic name:
ramipril systemic
Brand name:
Altace
Drug class:
Angiotensin Converting Enzyme Inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Zocor Rate Add review
Rx X N X
Generic name:
simvastatin systemic
Drug class:
statins
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
telmisartan 10 1 review for telmisartan to treat Cardiovascular Risk Reduction
Rx D N X
Generic name:
telmisartan systemic
Brand name:
Micardis
Drug class:
angiotensin receptor blockers
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Xarelto 7.0 1 review for Xarelto to treat Cardiovascular Risk Reduction
Rx C N
Generic name:
rivaroxaban systemic
Drug class:
factor Xa inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
empagliflozin 5.1 10 reviews for empagliflozin to treat Cardiovascular Risk Reduction
Rx C N X
Generic name:
empagliflozin systemic
Brand name:
Jardiance
Drug class:
SGLT-2 inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
Micardis Rate Add review
Rx D N X
Generic name:
telmisartan systemic
Drug class:
angiotensin receptor blockers
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Vascepa 5.4 9 reviews for Vascepa to treat Cardiovascular Risk Reduction
Rx C N
Generic name:
icosapent systemic
Drug class:
miscellaneous antihyperlipidemic agents
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Trulicity 5.2 17 reviews for Trulicity to treat Cardiovascular Risk Reduction
Rx C N X
Generic name:
dulaglutide systemic
Drug class:
incretin mimetics
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
liraglutide 6.3 4 reviews for liraglutide to treat Cardiovascular Risk Reduction
Rx C N X
Generic name:
liraglutide systemic
Brand name:
Victoza
Drug class:
incretin mimetics
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
Victoza 6.3 4 reviews for Victoza to treat Cardiovascular Risk Reduction
Rx C N X
Generic name:
liraglutide systemic
Drug class:
incretin mimetics
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
FloLipid Rate Add review
Rx X N X
Generic name:
simvastatin systemic
Drug class:
statins
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Praluent 6.4 28 reviews for Praluent to treat Cardiovascular Risk Reduction
Rx N
Generic name:
alirocumab systemic
Drug class:
PCSK9 inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Brilinta 2.3 4 reviews for Brilinta to treat Cardiovascular Risk Reduction
Rx C N
Generic name:
ticagrelor systemic
Drug class:
platelet aggregation inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
rivaroxaban 4.0 2 reviews for rivaroxaban to treat Cardiovascular Risk Reduction
Rx C N
Generic name:
rivaroxaban systemic
Brand name:
Xarelto
Drug class:
factor Xa inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
alirocumab 6.4 28 reviews for alirocumab to treat Cardiovascular Risk Reduction
Rx N
Generic name:
alirocumab systemic
Brand name:
Praluent
Drug class:
PCSK9 inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
Altace Rate Add review
Rx D N X
Generic name:
ramipril systemic
Drug class:
Angiotensin Converting Enzyme Inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
icosapent 5.3 10 reviews for icosapent to treat Cardiovascular Risk Reduction
Rx C N
Generic name:
icosapent systemic
Brand name:
Vascepa
Drug class:
miscellaneous antihyperlipidemic agents
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Invokana Rate Add review
Rx C N X
Generic name:
canagliflozin systemic
Drug class:
SGLT-2 inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
canagliflozin / metformin Rate Add review
Rx C N X
Generic name:
canagliflozin / metformin systemic
Brand names:
Invokamet, Invokamet XR
Drug class:
antidiabetic combinations
For consumers:
dosage, interactions, side effects

Frequently asked questions

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Rating For ratings, users were asked how effective they found the medicine while considering positive/adverse effects and ease of use (1 = not effective, 10 = most effective).
Activity Activity is based on recent site visitor activity relative to other medications in the list.
Rx Prescription only.
OTC Over-the-counter.
Rx/OTC Prescription or Over-the-counter.
Off-label This medication may not be approved by the FDA for the treatment of this condition.
EUA An Emergency Use Authorization (EUA) allows the FDA to authorize unapproved medical products or unapproved uses of approved medical products to be used in a declared public health emergency when there are no adequate, approved, and available alternatives.
Expanded Access Expanded Access is a potential pathway for a patient with a serious or immediately life-threatening disease or condition to gain access to an investigational medical product (drug, biologic, or medical device) for treatment outside of clinical trials when no comparable or satisfactory alternative therapy options are available.
Pregnancy Category
A Adequate and well-controlled studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).
B Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
C Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
D There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
X Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use in pregnant women clearly outweigh potential benefits.
N FDA has not classified the drug.
Controlled Substances Act (CSA) Schedule
M The drug has multiple schedules. The schedule may depend on the exact dosage form or strength of the medication.
U CSA Schedule is unknown.
N Is not subject to the Controlled Substances Act.
1 Has a high potential for abuse. Has no currently accepted medical use in treatment in the United States. There is a lack of accepted safety for use under medical supervision.
2 Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence.
3 Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence.
4 Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3.
5 Has a low potential for abuse relative to those in schedule 4. Has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 4.
Alcohol
X Interacts with Alcohol.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.