Skip to Content

SGLT-2 inhibitors

Other names: gliflozins, sodium-glucose cotransporter-2 inhibitors

What are SGLT-2 inhibitors?

SGLT-2 inhibitor is an abbreviation for sodium-glucose cotransporter-2 inhibitors. SGLT-2 inhibitors are a class of medicine used to lower high blood glucose levels in people with type 2 diabetes. They may also be called gliflozins. Available agents are canagliflozin, dapagliflozin, and empagliflozin.

SGLT-2 inhibitors inhibit SGLT-2 proteins located in the renal tubules of the kidneys which are responsible for reabsorbing glucose back into the blood. As a result, more glucose is excreted in the urine. SGLT-2 inhibitors have been shown to be effective at lowering hemoglobin A1c levels, improving weight loss and lowering blood pressure. They carry a low risk of hypoglycemia (low blood sugar levels). They are usually well tolerated.

SGLT-2 inhibitors may be used in the treatment of type 2 diabetes and act independently of beta-cell function in the pancreas.

List of SGLT-2 inhibitors:

Filter by:
Drug NameView by: Brand | Generic Reviews Avg. Ratings
Steglatro (Pro)
generic name: ertugliflozin
0 reviews
   
8.0
Invokana (Pro)
generic name: canagliflozin
228 reviews
   
6.2
Jardiance (Pro)
generic name: empagliflozin
91 reviews
   
6.2
Farxiga (Pro)
generic name: dapagliflozin
71 reviews
   
5.1

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

See Also

Medical conditions associated with SGLT-2 inhibitors:

Hide