Skip to main content
Print

Invokana Alternatives Compared

View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Invokana Remove Invokana from your drug comparison Metformin Remove Metformin from your drug comparison Januvia Remove Januvia from your drug comparison
View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Invokana canagliflozin Remove Invokana from your drug comparison Metformin Remove Metformin from your drug comparison Januvia sitagliptin Remove Januvia from your drug comparison

Invokana is effective at lowering blood glucose levels in people with type 2 diabetes. It also reduces the risk of future cardiovascular events (such as a heart attack or stroke) and kidney disease... View more

Metformin improves how the body responds to insulin and it is effective for the treatment of type 2 diabetes. Taste disturbances, diarrhea, and other stomach-related side effects are common side... View more

Januvia is a DDP-4 inhibitor that is used in addition to other medications for the treatment of type 2 diabetes. Rarely, it may cause joint pain, skin reactions, pancreatitis, or an allergic reaction... View more

Prescription only

Prescription only

Prescription only

Ratings & Reviews

View all 254 reviews

View all 592 reviews

View all 114 reviews

Drug Class

Side Effects

Common side effects include: vulvovaginal candidiasis, vaginal infection, vulvitis, vulvovaginitis, mean glomerular filtration rate decreased.

See the full Invokana side effects document.

Commonly reported side effects include: lactic acidosis, diarrhea, nausea, nausea and vomiting, vomiting, flatulence.

See the full metformin side effects document.

See the full Januvia side effects document.

Pricing and Coupons

* Prices are without insurance
Quantity 30 tablet
Dosage 100 mg
Per Unit* $19.23
Cost* $576.84

View all Invokana prices

Quantity 100 each
Dosage 500 mg
Per Unit* $0.16 - $0.21
Cost* $16.02 - $20.78

View all metformin prices

Quantity 30 tablet
Dosage 100 mg
Per Unit* $17.61
Cost* $528.16

View all Januvia prices

Get free Discount Card

Get free Discount Card

Get free Discount Card

Generic Availability

No

Yes (this medicine)

No

Dosage Form(s) Available
  • Oral tablet
  • Oral solution
  • Oral tablet
  • Oral tablet, extended release
  • Oral tablet

Brand Names

N/A

 Glumetza, Riomet, Riomet ER

N/A

Half Life

The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value.

13.1 hours

4.5 hours

12.4 hours

CSA Schedule**

View glossary of terms.
N
Not a controlled drug

Is not subject to the Controlled Substances Act.
N
Not a controlled drug

Is not subject to the Controlled Substances Act.
N
Not a controlled drug

Is not subject to the Controlled Substances Act.

Pregnancy Category
C
Category C Risk cannot be ruled out

See the full Pregnancy Warnings document.
B
Category B No proven risk in humans

See the full Pregnancy Warnings document.
B
Category B No proven risk in humans

See the full Pregnancy Warnings document.

Drug Interactions

A total of 360 drugs are known to interact with Invokana:

  • 2 major drug interactions (34 brand and generic names)
  • 337 moderate drug interactions (1489 brand and generic names)
  • 21 minor drug interactions (261 brand and generic names)

A total of 349 drugs are known to interact with metformin:

  • 19 major drug interactions (109 brand and generic names)
  • 301 moderate drug interactions (1449 brand and generic names)
  • 29 minor drug interactions (285 brand and generic names)

A total of 271 drugs are known to interact with Januvia:

  • 2 major drug interactions (5 brand and generic names)
  • 245 moderate drug interactions (1175 brand and generic names)
  • 24 minor drug interactions (273 brand and generic names)

Alcohol/Food/Lifestyle Interactions
  • Alcohol may affect blood glucose levels in patients with diabetes. Both hypoglycemia (low blood... View more
  • MetFORMIN should be taken with meals, and excessive alcohol intake (either short-term binge... View more
  • Alcohol may affect blood glucose levels in patients with diabetes. Both hypoglycemia (low blood... View more

Disease Interactions

First Approval Date

March 29, 2013

March 03, 1995

October 16, 2006

WADA Class

View World Anti-Doping Agency classifications.

N/A

N/A

N/A

More Information

Consumer Resources

Professional Resources

Related Treatment Guide

** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer

Compare Drugs

To view a detailed report comparing 3 or more drugs, please sign in or register.