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Semaglutide use while Breastfeeding

Drugs containing Semaglutide: Rybelsus, Ozempic

Medically reviewed by Drugs.com. Last updated on Aug 7, 2020.

Semaglutide Levels and Effects while Breastfeeding

Summary of Use during Lactation

No information is available on the clinical use of semaglutide during breastfeeding. Because semaglutide is a peptide molecule with a molecular weight of 4113 daltons and is over 99% protein bound, the amount in milk is likely to be very low. Absorption by the infant is unlikely because the drug is probably destroyed in the infant's gastrointestinal tract. Until more data become available, semaglutide should be used with caution during breastfeeding, especially while nursing a newborn or preterm infant.

Drug Levels

Maternal Levels. Relevant published information was not found as of the revision date.

Infant Levels. Relevant published information was not found as of the revision date.

Effects in Breastfed Infants

Relevant published information was not found as of the revision date.

Effects on Lactation and Breastmilk

Relevant published information was not found as of the revision date.

Alternate Drugs to Consider

Acarbose, Glipizide, Glyburide, Insulin, Metformin, Miglitol

Substance Identification

Substance Name

Semaglutide

CAS Registry Number

910463-68-2

Drug Class

  • Breast Feeding
  • Lactation
  • Hypoglycemic Agents
  • Incretins
  • Glucagon-Like Peptide-1 Agonists
  • GLP-1 Agonists

Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.

Further information

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