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GLP-1 Agonists (Incretin Mimetics)

Medically reviewed by Melisa Puckey, BPharm. Last updated on April 10, 2024.

Other names: GLP-1 Analogues, GLP-1 Receptor Agonists, glucagon-like peptide 1 agonists

What are GLP-1 Agonists (Incretin Mimetics)?

GLP-1 agonists are medications that help with weight loss and type 2 diabetes by mimicking the GLP-1 hormone. They increase insulin secretion, suppress glucagon release, slow gastric emptying, and reduce appetite. These effects lead to decreased caloric intake and improved satiety, and for type 2 diabetes, they improve blood sugar levels. Common examples include liraglutide and semaglutide. Clinical trials show significant weight loss and improvement in blood sugar levels, but side effects like nausea and vomiting can occur.

List of GLP-1 Agonists (Incretin Mimetics)

View by  Generic | Brand
Drug Name Avg. Rating Reviews
semaglutide systemic (Pro)
Brand names: Ozempic, Rybelsus, Wegovy
6.9
2,452 reviews
liraglutide systemic (Pro)
Brand names: Saxenda, Victoza
7.6
2,328 reviews
tirzepatide systemic (Pro)
Brand names: Mounjaro, Zepbound
8.7
1,613 reviews
dulaglutide systemic (Pro)
Brand name: Trulicity
5.3
994 reviews
exenatide systemic (Pro)
Brand names: Bydureon, Bydureon BCise, Byetta
6.4
417 reviews
albiglutide systemic
4.6
11 reviews
lixisenatide systemic (Pro)
Brand name: Adlyxin
No reviews
For ratings, users were asked how effective they found the medicine while considering positive/adverse effects and ease of use (1 = not effective, 10 = most effective).

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.