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Medications for Nonalcoholic Fatty Liver Disease

Other names: Fatty Liver; Idiopathic Fatty Liver; NAFLD; NASH; Nonalcoholic Steatohepatitis; Steatohepatitis; Steatosis

About Nonalcoholic Fatty Liver Disease

Nonalcoholic fatty liver disease (NAFLD) describes a range of conditions that affect people who drink little or no alcohol.

Drugs used to treat Nonalcoholic Fatty Liver Disease

The following list of medications are in some way related to, or used in the treatment of this condition.

Drug name Rating Reviews Activity ? Rx/OTC Pregnancy CSA Alcohol
ursodiol Off-label Rate Add review
Rx B N

Generic name: ursodiol systemic

Brand names:  Actigall, Urso, Urso Forte

Drug class: gallstone solubilizing agents

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Off-label: Yes

Actos Off-label Rate Add review
Rx C N X

Generic name: pioglitazone systemic

Drug class: thiazolidinediones

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Off-label: Yes

pioglitazone Off-label Rate Add review
Rx C N X

Generic name: pioglitazone systemic

Brand name:  Actos

Drug class: thiazolidinediones

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Off-label: Yes

Actigall Off-label Rate Add review
Rx B N

Generic name: ursodiol systemic

Drug class: gallstone solubilizing agents

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Off-label: Yes

orlistat Off-label 5.5 3 reviews
Rx/OTC X N

Generic name: orlistat systemic

Drug class: peripherally acting antiobesity agents

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph

Off-label: Yes

Avandia Off-label Rate Add review
Rx C N X

Generic name: rosiglitazone systemic

Drug class: thiazolidinediones

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Off-label: Yes

Urso Off-label Rate Add review
Rx B N

Generic name: ursodiol systemic

Drug class: gallstone solubilizing agents

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Off-label: Yes

betaine Off-label Rate Add review
Rx C N

Generic name: betaine systemic

Brand name:  Cystadane

Drug class: nutraceutical products

For consumers: dosage, side effects

Off-label: Yes

Urso Forte Off-label Rate Add review
Rx B N

Generic name: ursodiol systemic

Drug class: gallstone solubilizing agents

For consumers: dosage, interactions, side effects

Off-label: Yes

Cystadane Off-label Rate Add review
Rx C N

Generic name: betaine systemic

Drug class: nutraceutical products

For consumers: dosage, side effects

For professionals: Prescribing Information

Off-label: Yes

rosiglitazone Off-label Rate Add review
Rx C N X

Generic name: rosiglitazone systemic

Brand name:  Avandia

Drug class: thiazolidinediones

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Off-label: Yes

Alternative treatments for Nonalcoholic Fatty Liver Disease

The following products are considered to be alternative treatments or natural remedies for Nonalcoholic Fatty Liver Disease. Their efficacy may not have been scientifically tested to the same degree as the drugs listed in the table above. However there may be historical, cultural or anecdotal evidence linking their use to the treatment of Nonalcoholic Fatty Liver Disease.

Learn more about Nonalcoholic Fatty Liver Disease

Mayo Clinic Reference

Legend

Rating For ratings, users were asked how effective they found the medicine while considering positive/adverse effects and ease of use (1 = not effective, 10 = most effective).
Activity Activity is based on recent site visitor activity relative to other medications in the list.
Rx Prescription Only.
OTC Over the Counter.
Rx/OTC Prescription or Over the Counter.
Off-label This medication may not be approved by the FDA for the treatment of this condition.
Pregnancy Category
A Adequate and well-controlled studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).
B Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
C Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
D There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
X Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use in pregnant women clearly outweigh potential benefits.
N FDA has not classified the drug.
Controlled Substances Act (CSA) Schedule
N Is not subject to the Controlled Substances Act.
1 Has a high potential for abuse. Has no currently accepted medical use in treatment in the United States. There is a lack of accepted safety for use under medical supervision.
2 Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence.
3 Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence.
4 Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3.
5 Has a low potential for abuse relative to those in schedule 4. Has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 4.
Alcohol
X Interacts with Alcohol.

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Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.