Thiazolidinediones
Other names: glitazones
What are Thiazolidinediones?
Thiazolidinediones (also called glitazones) are a class of medicines that may be used for the treatment of type 2 diabetes. They are a type of oral hypoglycemic (a medicine that lowers blood glucose levels).
Thiazolidinediones bind to a receptor called the peroxisome proliferator activated receptor-gamma in adipocytes (fat cells) and promote maturation of fat cells and deposition of fat into peripheral tissues. By reducing circulating fat concentrations, thiazolidinediones improve a person with type 2 diabetes' sensitivity to insulin.
Thiazolidinediones may be used as monotherapy or in combination with other oral agents for type 2 diabetes, such as metformin or sulphonylureas. Weight gain and an increase in peripheral fat mass is a side effect of thiazolidinediones.
List of Thiazolidinediones
| Drug Name | Avg. Rating | Reviews |
|---|---|---|
| pioglitazone systemic (Pro) Brand name: Actos |
54 reviews | |
| rosiglitazone systemic Brand name: Avandia |
8 reviews | |
| For ratings, users were asked how effective they found the medicine while considering positive/adverse effects and ease of use (1 = not effective, 10 = most effective). | ||
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.