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Other names: glitazones

What are Thiazolidinediones?

Thiazolidinediones (also called glitazones) are a class of medicines that may be used for the treatment of type 2 diabetes. They are a type of oral hypoglycemic (a medicine that lowers blood glucose levels).

Thiazolidinediones bind to a receptor called the peroxisome proliferator activated receptor-gamma in adipocytes (fat cells) and promote maturation of fat cells and deposition of fat into peripheral tissues. By reducing circulating fat concentrations, thiazolidinediones improve a person with type 2 diabetes' sensitivity to insulin.

Thiazolidinediones may be used as monotherapy or in combination with other oral agents for type 2 diabetes, such as metformin or sulphonylureas. Weight gain and an increase in peripheral fat mass is a side effect of thiazolidinediones.

List of Thiazolidinediones:

View by: Brand | Generic

Drug Name Reviews Avg. Ratings
Avandia (Pro)
Generic name: rosiglitazone
8 reviews
Actos (Pro)
Generic name: pioglitazone
36 reviews

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

See Also

Medical conditions associated with thiazolidinediones: