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Thiazolidinediones

Other names: glitazones

What are Thiazolidinediones?

Thiazolidinediones (also called glitazones) are a class of medicines that may be used for the treatment of type 2 diabetes. They are a type of oral hypoglycemic (a medicine that lowers blood glucose levels).

Thiazolidinediones bind to a receptor called the peroxisome proliferator activated receptor-gamma in adipocytes (fat cells) and promote maturation of fat cells and deposition of fat into peripheral tissues. By reducing circulating fat concentrations, thiazolidinediones improve a person with type 2 diabetes' sensitivity to insulin.

Thiazolidinediones may be used as monotherapy or in combination with other oral agents for type 2 diabetes, such as metformin or sulphonylureas. Weight gain and an increase in peripheral fat mass is a side effect of thiazolidinediones.

List of Thiazolidinediones:

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Drug NameView by: Brand | Generic Reviews Avg. Ratings
Avandia (Pro)
generic name: rosiglitazone
8 reviews
   
5.4
Actos (Pro)
generic name: pioglitazone
33 reviews
   
5.1

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

See Also

Medical conditions associated with thiazolidinediones:

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