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Medications for Obesity

Other names: Overweight; Weight Gain

About Obesity

More than half of the U.S. population is overweight. But being obese is different from being overweight. An individual is considered obese when weight is 20% (25% in women) or more over the maximum desirable for their height. When an adult is more than 100 pounds overweight, it is considered morbid obesity.

Obesity is also defined as a BMI (body mass index) over 30 kg/m2. Patients with a BMI between 25 and 29.9 are considered overweight, but not obese. See also diet and calories.

Drugs used to treat Obesity

The following list of medications are in some way related to, or used in the treatment of this condition.

Drug name Rating Reviews Activity Rx/OTC Pregnancy CSA Alcohol
phentermine 8.7 602 reviews
Rx X 4 X

Generic name: phentermine systemic

Brand names:  Adipex-P, Lomaira, Atti-Plex P

Drug class: CNS stimulants, anorexiants

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Topamax Off Label 6.9 49 reviews
Rx D N X

Generic name: topiramate systemic

Drug class: carbonic anhydrase inhibitor anticonvulsants

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Off Label: Yes

Adipex-P 8.9 146 reviews
Rx X 4 X

Generic name: phentermine systemic

Drug class: CNS stimulants, anorexiants

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

topiramate Off Label 7.5 194 reviews
Rx D N X

Generic name: topiramate systemic

Brand names:  Topamax, Topamax Sprinkle

Drug class: carbonic anhydrase inhibitor anticonvulsants

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Off Label: Yes

Contrave 6.9 1166 reviews
Rx X N X

Generic name: bupropion / naltrexone systemic

Drug class: anorexiants

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Desoxyn 10 3 reviews
Rx C 2 X

Generic name: methamphetamine systemic

Drug class: CNS stimulants, anorexiants

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Alli 6.0 102 reviews
OTC X N

Generic name: orlistat systemic

Drug class: peripherally acting antiobesity agents

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

bupropion Off Label 7.9 26 reviews
Rx C N X

Generic name: bupropion systemic

Drug class: miscellaneous antidepressants, smoking cessation agents

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Off Label: Yes

Xenical 8.3 105 reviews
Rx X N

Generic name: orlistat systemic

Drug class: peripherally acting antiobesity agents

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

orlistat 7.3 321 reviews
Rx/OTC X N

Generic name: orlistat systemic

Brand names:  Alli, Xenical

Drug class: peripherally acting antiobesity agents

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph

phendimetrazine 8.3 145 reviews
Rx C 3 X

Generic name: phendimetrazine systemic

Brand names:  Bontril PDM, Fendique ER

Drug class: CNS stimulants, anorexiants

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Qsymia 8.2 174 reviews
Rx X 4 X

Generic name: phentermine / topiramate systemic

Drug class: anorexiants

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

diethylpropion 8.6 143 reviews
Rx B 4 X

Generic name: diethylpropion systemic

Drug class: CNS stimulants, anorexiants

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Saxenda 7.6 766 reviews
Rx C N X

Generic name: liraglutide systemic

Drug class: incretin mimetics

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

methamphetamine 10 4 reviews
Rx C 2 X

Generic name: methamphetamine systemic

Brand name:  Desoxyn

Drug class: CNS stimulants, anorexiants

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

lorcaserin 8.0 307 reviews
Rx X 4

Generic name: lorcaserin systemic

Drug class: anorexiants

For consumers: dosage, interactions,

For professionals: AHFS DI Monograph

Pregnyl Off Label 9.0 1 review
Rx X N

Generic name: chorionic gonadotropin (hcg) systemic

Drug class: gonadotropins

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Off Label: Yes

phentermine / topiramate 8.3 188 reviews
Rx X 4 X

Generic name: phentermine / topiramate systemic

Brand name:  Qsymia

Drug class: anorexiants

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts

Bontril PDM 6.8 4 reviews
Rx C 3 X

Generic name: phendimetrazine systemic

Drug class: CNS stimulants, anorexiants

For consumers: dosage, interactions, side effects

chorionic gonadotropin (hcg) Off Label 7.5 13 reviews
Rx X N

Generic name: chorionic gonadotropin (hcg) systemic

Brand name:  Pregnyl

Drug class: gonadotropins

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph, Natural Product Monographs, Prescribing Information

Off Label: Yes

methylphenidate Off Label 6.0 1 review
Rx C 2 X

Generic name: methylphenidate systemic

Drug class: CNS stimulants

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Off Label: Yes

Topamax Sprinkle Off Label 0.0 Add review
Rx D N X

Generic name: topiramate systemic

Drug class: carbonic anhydrase inhibitor anticonvulsants

For consumers: dosage, interactions, side effects

Off Label: Yes

benzphetamine 7.7 16 reviews
Rx X 3 X

Generic name: benzphetamine systemic

Drug class: CNS stimulants, anorexiants

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, Prescribing Information

bupropion / naltrexone 6.9 1200 reviews
Rx X N X

Generic name: bupropion / naltrexone systemic

Brand name:  Contrave

Drug class: anorexiants

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph

cimetidine Off Label 0.0 Add review
Rx/OTC B N X

Generic name: cimetidine systemic

Brand names:  Equaline Acid Reducer, Tagamet HB

Drug class: H2 antagonists

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Off Label: Yes

For ratings, users were asked how effective they found the medicine while considering positive/adverse effects and ease of use (1 = not effective, 10 = most effective).

Topics under Obesity

Alternative treatments for Obesity

The following products are considered to be alternative treatments or natural remedies for Obesity. Their efficacy may not have been scientifically tested to the same degree as the drugs listed in the table above. However there may be historical, cultural or anecdotal evidence linking their use to the treatment of Obesity.

Legend

Rx Prescription Only
OTC Over the Counter
Rx/OTC Prescription or Over the Counter
Off Label This medication may not be approved by the FDA for the treatment of this condition.
Pregnancy Category
A Adequate and well-controlled studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).
B Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
C Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
D There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
X Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use in pregnant women clearly outweigh potential benefits.
N FDA has not classified the drug.
Controlled Substances Act (CSA) Schedule
N Is not subject to the Controlled Substances Act.
1 Has a high potential for abuse. Has no currently accepted medical use in treatment in the United States. There is a lack of accepted safety for use under medical supervision.
2 Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence.
3 Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence.
4 Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3.
5 Has a low potential for abuse relative to those in schedule 4. Has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 4.
Alcohol
X Interacts with Alcohol.

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Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.