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Medications for Obesity

Other names: Overweight; Weight Gain

About Obesity:  More than half of the U.S. population is overweight. But being obese is different from being overweight. An individual is considered obese when weight is 20% (25% in women) or more over the maximum desirable for their height. When an adult is more than 100 pounds overweight, it is considered morbid obesity.

Obesity is also defined as a BMI (body mass index) over 30 kg/m2. Patients with a BMI between 25 and 29.9 are considered overweight, but not obese. See also diet and calories.

Drugs Used to Treat Obesity

The following list of medications are in some way related to, or used in the treatment of this condition.

Drug name Rx / OTC Pregnancy CSA Alcohol Reviews Rating Popularity
phentermine X 4 X 600 reviews
8.7

Generic name: phentermine systemic

Brand names:  Adipex-P, Lomaira, Atti-Plex P

Drug class: CNS stimulants, anorexiants

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Adipex-P X 4 X 146 reviews
8.9

Generic name: phentermine systemic

Drug class: CNS stimulants, anorexiants

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

topiramate Off Label D N X 193 reviews
7.4

Generic name: topiramate systemic

Brand names:  Topamax, Topamax Sprinkle

Drug class: carbonic anhydrase inhibitor anticonvulsants

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Off Label: Yes

Topamax Off Label D N X 49 reviews
6.9

Generic name: topiramate systemic

Drug class: carbonic anhydrase inhibitor anticonvulsants

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

Off Label: Yes

Contrave X N X 1159 reviews
6.9

Generic name: bupropion / naltrexone systemic

Drug class: anorexiants

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

Desoxyn C 2 X 3 reviews
10

Generic name: methamphetamine systemic

Drug class: CNS stimulants, anorexiants

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

Alli X N 102 reviews
6.0

Generic name: orlistat systemic

Drug class: peripherally acting antiobesity agents

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

phendimetrazine C 3 X 144 reviews
8.3

Generic name: phendimetrazine systemic

Brand names:  Bontril PDM, Fendique ER

Drug class: CNS stimulants, anorexiants

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

bupropion Off Label C N X 19 reviews
9.0

Generic name: bupropion systemic

Drug class: miscellaneous antidepressants, smoking cessation agents

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Off Label: Yes

Xenical X N 104 reviews
8.3

Generic name: orlistat systemic

Drug class: peripherally acting antiobesity agents

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

orlistat X N 317 reviews
7.3

Generic name: orlistat systemic

Brand names:  Alli, Xenical

Drug class: peripherally acting antiobesity agents

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph

Qsymia X 4 X 174 reviews
8.2

Generic name: phentermine / topiramate systemic

Drug class: anorexiants

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

diethylpropion B 4 X 137 reviews
8.9

Generic name: diethylpropion systemic

Drug class: CNS stimulants, anorexiants

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Saxenda C N X 760 reviews
7.6

Generic name: liraglutide systemic

Drug class: incretin mimetics

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

methamphetamine C 2 X 4 reviews
10

Generic name: methamphetamine systemic

Brand name:  Desoxyn

Drug class: CNS stimulants, anorexiants

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

lorcaserin X 4 306 reviews
8.0

Generic name: lorcaserin systemic

Drug class: anorexiants

For consumers: dosage, interactions,

For professionals: AHFS DI Monograph

Pregnyl Off Label X N 1 review
9.0

Generic name: chorionic gonadotropin (hcg) systemic

Drug class: gonadotropins

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Off Label: Yes

phentermine / topiramate X 4 X 188 reviews
8.3

Generic name: phentermine / topiramate systemic

Brand name:  Qsymia

Drug class: anorexiants

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts

Bontril PDM C 3 X 4 reviews
6.8

Generic name: phendimetrazine systemic

Drug class: CNS stimulants, anorexiants

For consumers: dosage, interactions, side effects

bupropion / naltrexone X N X 1193 reviews
6.9

Generic name: bupropion / naltrexone systemic

Brand name:  Contrave

Drug class: anorexiants

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph

chorionic gonadotropin (hcg) Off Label X N 13 reviews
7.5

Generic name: chorionic gonadotropin (hcg) systemic

Brand name:  Pregnyl

Drug class: gonadotropins

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph, Natural Product Monographs, Prescribing Information

Off Label: Yes

liraglutide C N X 855 reviews
7.7

Generic name: liraglutide systemic

Brand name:  Saxenda

Drug class: incretin mimetics

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph

Lomaira X 4 X 15 reviews
7.0

Generic name: phentermine systemic

Drug class: anorexiants

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

methylphenidate Off Label C 2 X 1 review
6.0

Generic name: methylphenidate systemic

Drug class: CNS stimulants

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Off Label: Yes

Topamax Sprinkle Off Label D N X Add review
0.0

Generic name: topiramate systemic

Drug class: carbonic anhydrase inhibitor anticonvulsants

For consumers: dosage, interactions, side effects

Off Label: Yes

Topics under Obesity

Alternative treatments for Obesity

The following products are considered to be alternative treatments or natural remedies for Obesity. Their efficacy may not have been scientifically tested to the same degree as the drugs listed in the table above. However there may be historical, cultural or anecdotal evidence linking their use to the treatment of Obesity.

Legend

Rx Prescription Only
OTC Over the Counter
Rx/OTC Prescription or Over the Counter
Off Label This medication may not be approved by the FDA for the treatment of this condition.
Pregnancy Category
A Adequate and well-controlled studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).
B Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
C Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
D There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
X Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use in pregnant women clearly outweigh potential benefits.
N FDA has not classified the drug.
Controlled Substances Act (CSA) Schedule
N Is not subject to the Controlled Substances Act.
1 Has a high potential for abuse. Has no currently accepted medical use in treatment in the United States. There is a lack of accepted safety for use under medical supervision.
2 Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence.
3 Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence.
4 Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3.
5 Has a low potential for abuse relative to those in schedule 4. Has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 4.
Alcohol
X Interacts with Alcohol.

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Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.