Bupropion Interactions
There are 559 drugs known to interact with bupropion, along with 7 disease interactions, and 1 alcohol/food interaction. Of the total drug interactions, 218 are major, 336 are moderate, and 5 are minor.
- View all 559 medications that may interact with bupropion
- View bupropion alcohol/food interactions (1)
- View bupropion disease interactions (7)
Most frequently checked interactions
View interaction reports for bupropion and the medicines listed below.
- Abilify (aripiprazole)
- Adderall (amphetamine / dextroamphetamine)
- Adderall XR (amphetamine / dextroamphetamine)
- Aspir 81 (aspirin)
- Aspirin Low Strength (aspirin)
- Benadryl (diphenhydramine)
- CoQ10 (ubiquinone)
- Cymbalta (duloxetine)
- Eliquis (apixaban)
- Fish Oil (omega-3 polyunsaturated fatty acids)
- Flonase (fluticasone nasal)
- Lamictal (lamotrigine)
- Lexapro (escitalopram)
- Lyrica (pregabalin)
- Metoprolol Succinate ER (metoprolol)
- Metoprolol Tartrate (metoprolol)
- Ozempic (semaglutide)
- Probiotic Formula (bifidobacterium infantis / lactobacillus acidophilus)
- Prozac (fluoxetine)
- Singulair (montelukast)
- Synthroid (levothyroxine)
- Tylenol (acetaminophen)
- Vitamin B12 (cyanocobalamin)
- Vitamin C (ascorbic acid)
- Vitamin D2 (ergocalciferol)
- Vitamin D3 (cholecalciferol)
- Vyvanse (lisdexamfetamine)
- Xanax (alprazolam)
- Zoloft (sertraline)
- Zyrtec (cetirizine)
Bupropion alcohol/food interactions
There is 1 alcohol/food interaction with bupropion.
Bupropion disease interactions
There are 7 disease interactions with bupropion which include:
- suicidality
- seizure disorders
- angle closure glaucoma
- liver disease
- mixed/manic episode
- renal dysfunction
- weight loss
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- Drug class: miscellaneous antidepressants
- Breastfeeding
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
