Bupropion Alternatives Compared
Bupropion Remove Bupropion from your drug comparison | Cymbalta Remove Cymbalta from your drug comparison | Zoloft Remove Zoloft from your drug comparison |
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Bupropion Remove Bupropion from your drug comparison | Cymbalta duloxetine Remove Cymbalta from your drug comparison | Zoloft sertraline Remove Zoloft from your drug comparison | ||||||||||||||||||||||||
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Bupropion may be used in the treatment of depression or as an aid to smoking cessation; however, side effects may include insomnia, neuropsychiatric adverse events, or seizures. It carries a black... View more |
Cymbalta has antidepressant, anti-anxiety, and pain-relieving properties; however, it has been associated with a discontinuation syndrome on withdrawal even when tapered. Prescribed for Back Pain,... View more |
Zoloft is an effective antidepressant with less potential for drowsiness than many other antidepressants. Prescribed for Panic Disorder, Obsessive Compulsive Disorder, Major Depressive Disorder,... View more |
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Prescription only |
Prescription only |
Prescription only |
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Ratings & Reviews |
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Drug Class |
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Side Effects |
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Commonly reported side effects include: insomnia, nausea, pharyngitis, weight loss, constipation, dizziness, headache, xerostomia. See the full bupropion side effects document. |
Common side effects include: asthenia, constipation, diarrhea, dizziness, drowsiness, fatigue, hypersomnia, insomnia, nausea, sedated state, headache, xerostomia. See the full Cymbalta side effects document. |
Common side effects include: diarrhea, dizziness, drowsiness, dyspepsia, fatigue, insomnia, loose stools, nausea, tremor, headache, paresthesia, anorexia, decreased libido, delayed ejaculation, diaphoresis, ejaculation failure, xerostomia. See the full Zoloft side effects document. |
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Pricing and Coupons* Prices are without insurance |
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View all bupropion prices |
View all Cymbalta prices and generic prices |
View all Zoloft prices and generic prices |
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Generic Availability |
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Yes (this medicine) |
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Dosage Form(s) Available |
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Brand Names |
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Aplenzin, Budeprion, Budeprion SR, Forfivo XL, Wellbutrin SR, Wellbutrin XL | Other duloxetine brands include: Drizalma Sprinkle, Irenka |
N/A |
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Half LifeThe half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. |
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30 hours |
17 hours |
66 hours |
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CSA Schedule**View glossary of terms. |
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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Pregnancy Category |
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Category C
Risk cannot be ruled out
See the full Pregnancy Warnings document. |
Category C
Risk cannot be ruled out
See the full Pregnancy Warnings document. |
Category C
Risk cannot be ruled out
See the full Pregnancy Warnings document. |
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FDA Alerts |
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Drug Interactions |
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A total of 422 drugs are known to interact with bupropion:
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A total of 562 drugs are known to interact with Cymbalta:
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A total of 618 drugs are known to interact with Zoloft:
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Alcohol/Food/Lifestyle Interactions |
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Disease Interactions |
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First Approval Date |
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December 30, 1985 |
N/A |
December 30, 1991 |
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WADA ClassView World Anti-Doping Agency classifications. |
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N/A |
N/A |
N/A |
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More Information |
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Consumer Resources |
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Professional Resources |
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Related Treatment Guide |
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** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.