Skip to main content

Medications for Dysautonomia

Dysautonomia is a general term used to describe a breakdown, or failure of the autonomic nervous system.

Drugs used to treat Dysautonomia

The following list of medications are in some way related to or used in the treatment of this condition.

Drug name Rating Reviews Activity ? Rx/OTC Pregnancy CSA Alcohol
midodrine Off-label 8.9 8 reviews
Rx C N

Generic name: midodrine systemic

Brand name:  Orvaten

Drug class: miscellaneous cardiovascular agents

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

Off-label: Yes

fludrocortisone Off-label 5.0 6 reviews
Rx C N

Generic name: fludrocortisone systemic

Brand names:  Florinef, Florinef Acetate

Drug class: mineralocorticoids

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

Off-label: Yes

Mestinon Off-label 6.4 9 reviews
Rx C N

Generic name: pyridostigmine systemic

Drug class: cholinergic muscle stimulants

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Off-label: Yes

pyridostigmine Off-label 7.2 12 reviews
Rx C N

Generic name: pyridostigmine systemic

Brand names:  Mestinon, Mestinon Timespan, Regonol

Drug class: cholinergic muscle stimulants

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

Off-label: Yes

Florinef Off-label Rate Add review
Rx C N

Generic name: fludrocortisone systemic

Drug class: mineralocorticoids

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Off-label: Yes

Ativan Off-label 10 1 review
Rx D 4 X

Generic name: lorazepam systemic

Drug class: benzodiazepines, miscellaneous antiemetics, benzodiazepine anticonvulsants

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Off-label: Yes

alprazolam Off-label 9.8 11 reviews
Rx D 4 X

Generic name: alprazolam systemic

Drug class: benzodiazepines

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

Off-label: Yes

amitriptyline Off-label 8.0 1 review
Rx C N X

Generic name: amitriptyline systemic

Drug class: tricyclic antidepressants

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

Off-label: Yes

lorazepam Off-label 10 1 review
Rx D 4 X

Generic name: lorazepam systemic

Brand names:  Ativan, Lorazepam Intensol

Drug class: benzodiazepines, miscellaneous antiemetics, benzodiazepine anticonvulsants

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

Off-label: Yes

sertraline Off-label Rate Add review
Rx C N X

Generic name: sertraline systemic

Drug class: selective serotonin reuptake inhibitors

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

Off-label: Yes

fluoxetine Off-label Rate Add review
Rx C N X

Generic name: fluoxetine systemic

Drug class: selective serotonin reuptake inhibitors

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

Off-label: Yes

ibuprofen Rate Add review
Rx/OTC C N X

Generic name: ibuprofen systemic

Brand names:  Proprinal, Advil, A-G Profen, Actiprofen, Addaprin, Motrin, Nuprin, Genpril, IBU-200, Midol IB, Motrin IB …show all

Drug class: Nonsteroidal anti-inflammatory drugs

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

Lorazepam Intensol Off-label Rate Add review
Rx D 4 X

Generic name: lorazepam systemic

Drug class: benzodiazepines, miscellaneous antiemetics, benzodiazepine anticonvulsants

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Off-label: Yes

naproxen Rate Add review
Rx/OTC C N X

Generic name: naproxen systemic

Brand names:  Aleve, Anaprox, Anaprox-DS, Flanax Pain Reliever, Naprelan, Naprosyn, Aflaxen, All Day Pain Relief, All Day Relief, EC-Naprosyn …show all

Drug class: Nonsteroidal anti-inflammatory drugs

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

Paxil Off-label 8.0 1 review
Rx D N X

Generic name: paroxetine systemic

Drug class: selective serotonin reuptake inhibitors

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Off-label: Yes

nortriptyline Off-label 1.0 2 reviews
Rx N N X

Generic name: nortriptyline systemic

Drug class: tricyclic antidepressants

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

Off-label: Yes

Proprinal Rate Add review
Rx/OTC C N X

Generic name: ibuprofen systemic

Drug class: Nonsteroidal anti-inflammatory drugs

For consumers: dosage, interactions, side effects

Advil Rate Add review
Rx/OTC C N X

Generic name: ibuprofen systemic

Drug class: Nonsteroidal anti-inflammatory drugs

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

A-G Profen Rate Add review
Rx/OTC C N X

Generic name: ibuprofen systemic

Drug class: Nonsteroidal anti-inflammatory drugs

For consumers: dosage, interactions, side effects

Actiprofen Rate Add review
Rx/OTC C N X

Generic name: ibuprofen systemic

Drug class: Nonsteroidal anti-inflammatory drugs

For consumers: dosage, interactions, side effects

Addaprin Rate Add review
Rx/OTC C N X

Generic name: ibuprofen systemic

Drug class: Nonsteroidal anti-inflammatory drugs

For consumers: dosage, interactions, side effects

Motrin Rate Add review
Rx/OTC C N X

Generic name: ibuprofen systemic

Drug class: Nonsteroidal anti-inflammatory drugs

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Nuprin Rate Add review
Rx/OTC C N X

Generic name: ibuprofen systemic

Drug class: Nonsteroidal anti-inflammatory drugs

For consumers: dosage, interactions, side effects

paroxetine Off-label 8.0 1 review
Rx D N X

Generic name: paroxetine systemic

Brand names:  Paxil, Paxil CR, Pexeva

Drug class: selective serotonin reuptake inhibitors

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

Off-label: Yes

Aleve Rate Add review
Rx/OTC C N X

Generic name: naproxen systemic

Drug class: Nonsteroidal anti-inflammatory drugs

For consumers: dosage, interactions, side effects

Topics under Dysautonomia

Learn more about Dysautonomia

Symptoms and treatments

Medicine.com guides (external)

Legend

Rating For ratings, users were asked how effective they found the medicine while considering positive/adverse effects and ease of use (1 = not effective, 10 = most effective).
Activity Activity is based on recent site visitor activity relative to other medications in the list.
Rx Prescription only.
OTC Over-the-counter.
Rx/OTC Prescription or Over-the-counter.
Off-label This medication may not be approved by the FDA for the treatment of this condition.
EUA An Emergency Use Authorization (EUA) allows the FDA to authorize unapproved medical products or unapproved uses of approved medical products to be used in a declared public health emergency when there are no adequate, approved, and available alternatives.
Pregnancy Category
A Adequate and well-controlled studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).
B Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
C Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
D There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
X Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use in pregnant women clearly outweigh potential benefits.
N FDA has not classified the drug.
Controlled Substances Act (CSA) Schedule
M The drug has multiple schedules. The schedule may depend on the exact dosage form or strength of the medication.
U CSA Schedule is unknown.
N Is not subject to the Controlled Substances Act.
1 Has a high potential for abuse. Has no currently accepted medical use in treatment in the United States. There is a lack of accepted safety for use under medical supervision.
2 Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence.
3 Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence.
4 Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3.
5 Has a low potential for abuse relative to those in schedule 4. Has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 4.
Alcohol
X Interacts with Alcohol.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.