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Lorazepam Dosage

Medically reviewed by Drugs.com. Last updated on Aug 16, 2023.

Applies to the following strengths: 1 mg; 2 mg; 0.5 mg; 4 mg/mL; 2 mg/mL; 1 mg/mL-NaCl 0.9%; 1.5 mg; 3 mg; 200 mg/200 mL-D5%

Usual Adult Dose for:

Usual Geriatric Dose for:

Usual Pediatric Dose for:

Additional dosage information:

Usual Adult Dose for Anxiety

ORAL:
Initial dose: 2 to 3 mg orally per day, given 2 to 3 times per day
Maintenance dose: 1 to 2 mg orally 2 to 3 times a day

Comments:


Uses:

Usual Adult Dose for Light Anesthesia

INJECTION:
IM: 0.05 mg/kg IM ONCE


IV: 2 mg total OR 0.044 mg/kg IV ONCE, whichever is smaller

Comments:

Use: As a preanesthetic medication to produce sedation (sleepiness or drowsiness), relieve anxiety, and decrease the ability to recall events related to the day of surgery

Usual Adult Dose for Status Epilepticus

INJECTION: 4 mg IV given at a rate of 2 mg/min; may repeat the dose in 10 to 15 minutes


Comments:

Use: Treatment of status epilepticus

Usual Adult Dose for Insomnia

ORAL: 2 to 4 mg orally once a day at bedtime

Comments:


Use: Management of insomnia due to anxiety of transient situational stress

Usual Geriatric Dose for Anxiety

ORAL:
Older or debilitated patients:


Comments:

Uses:

Usual Pediatric Dose for Anxiety

ORAL:
12 years or older:



Uses:

Usual Pediatric Dose for Insomnia

ORAL:
12 years or older: 2 to 4 mg orally once a day at bedtime

Comments:


Use: Management of insomnia

Renal Dose Adjustments

INJECTION:


ORAL: Use with caution.

Liver Dose Adjustments

INJECTION: No adjustment recommended.

ORAL:

Dose Adjustments

Doses should be reduced by 50% when coadministered with probenecid or valproate.

INJECTION: It may be necessary to increase the dose in female patients who are concomitantly taking oral contraceptives.

Precautions

US BOXED WARNINGS:
RISKS FROM CONCOMITANT USE WITH OPIOIDS:

Recommendations:
ABUSE, MISUSE, AND ADDICTION:
Recommendation:
DEPENDENCE AND WITHDRAWAL REACTIONS:
Recommendation:

INJECTION CONTRAINDICATIONS:

ORAL CONTRAINDICATIONS:

Safety and efficacy of oral formulations have not been established in patients younger than 12 years.

Safety and efficacy of injection formulations have not been established in patients younger than 18 years.

Consult WARNINGS section for additional precautions.

US Controlled Substance: Schedule IV

Dialysis

Data not available

Other Comments

Administration advice:


Storage requirements:

Reconstitution/preparation techniques:

IV compatibility:

General:

Monitoring:

Patient advice:

Frequently asked questions

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.