Medications for Postural Orthostatic Tachycardia Syndrome
Other names: Chronic Orthostatic Intolerance; Postural Tachycardia Syndrome; POTS
What is Postural Orthostatic Tachycardia Syndrome: Postural orthostatic tachycardia syndrome (POTS) is a condition in which an excessively reduced volume of blood returns to the heart after an individual stands up from a lying down position. The primary symptom is lightheadedness or fainting.
Medications to treat Postural Orthostatic Tachycardia Syndrome
The following list of medications are in some way related to, or used in the treatment of this condition.
| Drug name | Rx / OTC | Pregnancy | CSA | Alcohol | Reviews | Rating | Popularity |
|---|---|---|---|---|---|---|---|
| midodrine Off Label | Rx | C | N | 10 reviews | |||
|
Generic name: midodrine systemic Brand name: Orvaten Drug class: miscellaneous cardiovascular agents For consumers: dosage, interactions, side effects For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information Off Label: Yes |
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| fludrocortisone Off Label | Rx | C | N | 10 reviews | |||
|
Generic name: fludrocortisone systemic Brand names: Florinef, Florinef Acetate Drug class: mineralocorticoids For consumers: dosage, interactions, side effects For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information Off Label: Yes |
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| Florinef Off Label | Rx | C | N | 4 reviews | |||
|
Generic name: fludrocortisone systemic Drug class: mineralocorticoids For consumers: dosage, interactions, side effects For professionals: Prescribing Information Off Label: Yes |
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| sodium chloride | Rx/OTC | C | N | Add review | Add | ||
|
Generic name: sodium chloride systemic Drug class: minerals and electrolytes, miscellaneous respiratory agents For consumers: interactions, side effects For professionals: AHFS DI Monograph, Prescribing Information |
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| clonidine Off Label | Rx | C | N | X | 1 review | ||
|
Generic name: clonidine systemic Drug class: antiadrenergic agents, centrally acting For consumers: dosage, interactions, side effects For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information Off Label: Yes |
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| Orvaten Off Label | Rx | C | N | 1 review | |||
|
Generic name: midodrine systemic Drug class: miscellaneous cardiovascular agents For consumers: dosage, interactions, side effects For professionals: AHFS DI Monograph Off Label: Yes |
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| methylphenidate Off Label | Rx | C | 2 | X | 1 review | ||
|
Generic name: methylphenidate systemic Drug class: CNS stimulants For consumers: dosage, interactions, side effects For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information Off Label: Yes |
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| bupropion Off Label | Rx | C | N | X | 2 reviews | ||
|
Generic name: bupropion systemic Drug class: miscellaneous antidepressants, smoking cessation agents For consumers: dosage, interactions, side effects For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information Off Label: Yes |
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| Florinef Acetate Off Label | Rx | C | N | 2 reviews | |||
|
Generic name: fludrocortisone systemic Drug class: mineralocorticoids For consumers: dosage, interactions, side effects For professionals: AHFS DI Monograph Off Label: Yes |
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| labetalol Off Label | Rx | C | N | X | Add review | Add | |
|
Generic name: labetalol systemic Drug class: non-cardioselective beta blockers For consumers: dosage, interactions, side effects For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information Off Label: Yes |
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| octreotide Off Label | Rx | B | N | Add review | Add | ||
|
Generic name: octreotide systemic Drug class: somatostatin and somatostatin analogs For consumers: dosage, interactions, side effects For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information Off Label: Yes |
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Legend
| Off Label | This medication may not be approved by the FDA for the treatment of this condition. |
| Prescription Only / Over the Counter | |
|---|---|
| Rx | Prescription Only |
| OTC | Over the Counter |
| Rx/OTC | Prescription or Over the Counter |
| Pregnancy | |
|---|---|
| A | Adequate and well-controlled studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters). |
| B | Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women. |
| C | Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use in pregnant women despite potential risks. |
| D | There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use in pregnant women despite potential risks. |
| X | Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use in pregnant women clearly outweigh potential benefits. |
| N | FDA has not classified the drug. |
| Controlled Substances Act Schedule | |
|---|---|
| N | Is not subject to the Controlled Substances Act. |
| 1 | Has a high potential for abuse. Has no currently accepted medical use in treatment in the United States. There is a lack of accepted safety for use under medical supervision. |
| 2 | Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence. |
| 3 | Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence. |
| 4 | Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3. |
| 5 | Has a low potential for abuse relative to those in schedule 4. Has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 4. |
| Alcohol | |
|---|---|
| X | Interacts with Alcohol. |

