Motrin Interactions
There are 415 drugs known to interact with Motrin (ibuprofen), along with 11 disease interactions, and 2 alcohol/food interactions. Of the total drug interactions, 99 are major, 301 are moderate, and 15 are minor.
- View all 415 medications that may interact with Motrin
- View Motrin alcohol/food interactions (2)
- View Motrin disease interactions (11)
Most frequently checked interactions
View interaction reports for Motrin (ibuprofen) and the medicines listed below.
- albuterol
- aspirin
- atorvastatin
- baclofen
- Benadryl (diphenhydramine)
- Claritin (loratadine)
- Cymbalta (duloxetine)
- Flexeril (cyclobenzaprine)
- Flonase (fluticasone nasal)
- gabapentin
- hydrochlorothiazide
- levothyroxine
- lisinopril
- melatonin
- metformin
- MiraLAX (polyethylene glycol 3350)
- Norco (acetaminophen / hydrocodone)
- omeprazole
- prednisone
- Singulair (montelukast)
- Synthroid (levothyroxine)
- tramadol
- trazodone
- Tylenol (acetaminophen)
- Vitamin B12 (cyanocobalamin)
- Vitamin C (ascorbic acid)
- Vitamin D3 (cholecalciferol)
- Xanax (alprazolam)
- Zoloft (sertraline)
- Zyrtec (cetirizine)
Motrin alcohol/food interactions
There are 2 alcohol/food interactions with Motrin (ibuprofen).
Motrin disease interactions
There are 11 disease interactions with Motrin (ibuprofen) which include:
- asthma
- fluid retention
- GI toxicity
- rash
- renal toxicities
- thrombosis
- PKU
- anemia
- hepatotoxicity
- hyperkalemia
- platelet aggregation inhibition
Report options
More about Motrin (ibuprofen)
- Compare alternatives
- Reviews (16)
- Drug images
- Latest FDA alerts (14)
- Side effects
- Dosage information
- During pregnancy
- Support group
- Drug class: Nonsteroidal anti-inflammatory drugs
- Breastfeeding
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Amitriptyline
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Hydroxyzine
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Tramadol
Tramadol is an opioid medication that may be used to treat moderate to moderately severe chronic ...
Cyclobenzaprine
Cyclobenzaprine is a muscle relaxant and works by blocking pain sensations. Includes ...
Duloxetine
Duloxetine is a selective serotonin and norepinephrine reuptake inhibitor antidepressant used to ...
Meloxicam
Meloxicam is a nonsteroidal anti-inflammatory drug used to treat pain or inflammation caused by ...
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
