Motrin Interactions
There are 414 drugs known to interact with Motrin (ibuprofen), along with 11 disease interactions, and 2 alcohol/food interactions. Of the total drug interactions, 99 are major, 300 are moderate, and 15 are minor.
- View all 414 medications that may interact with Motrin
- View Motrin alcohol/food interactions (2)
- View Motrin disease interactions (11)
Most frequently checked interactions
View interaction reports for Motrin (ibuprofen) and the medicines listed below.
- albuterol
- amlodipine
- aspirin
- atorvastatin
- Benadryl (diphenhydramine)
- Claritin (loratadine)
- Cymbalta (duloxetine)
- Flexeril (cyclobenzaprine)
- Flonase (fluticasone nasal)
- gabapentin
- hydrochlorothiazide
- levothyroxine
- lisinopril
- melatonin
- metformin
- MiraLAX (polyethylene glycol 3350)
- Norco (acetaminophen / hydrocodone)
- omeprazole
- prednisone
- Singulair (montelukast)
- Synthroid (levothyroxine)
- tramadol
- trazodone
- Tylenol (acetaminophen)
- Vitamin B12 (cyanocobalamin)
- Vitamin C (ascorbic acid)
- Vitamin D3 (cholecalciferol)
- Xanax (alprazolam)
- Zoloft (sertraline)
- Zyrtec (cetirizine)
Motrin alcohol/food interactions
There are 2 alcohol/food interactions with Motrin (ibuprofen).
Motrin disease interactions
There are 11 disease interactions with Motrin (ibuprofen) which include:
- asthma
- fluid retention
- GI toxicity
- rash
- renal toxicities
- thrombosis
- PKU
- anemia
- hepatotoxicity
- hyperkalemia
- platelet aggregation inhibition
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More about Motrin (ibuprofen)
- Compare alternatives
- Reviews (16)
- Drug images
- Latest FDA alerts (14)
- Side effects
- Dosage information
- During pregnancy
- Support group
- Drug class: Nonsteroidal anti-inflammatory drugs
- Breastfeeding
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
