Paroxetine Drug Interactions
A total of 912 drugs are known to interact with paroxetine.
- 224 major drug interactions
- 652 moderate drug interactions
- 36 minor drug interactions
Check for interactions with paroxetine
Common medications checked in combination with paroxetine
- Adderall (amphetamine / dextroamphetamine)
- Advair Diskus (fluticasone / salmeterol)
- alprazolam (Xanax, Alprazolam Intensol, Xanax XR, Niravam)
- amitriptyline (Elavil, Endep, Vanatrip)
- Aspirin Low Strength (aspirin)
- Calcium 600 D (calcium / vitamin d)
- Crestor (rosuvastatin)
- diazepam (Valium, Diastat, Diazepam Intensol, Diastat AcuDial, Zetran, Diastat Pediatric, Dizac, Valrelease)
- diphenhydramine (Benadryl, Banophen, Benadryl Allergy, ZzzQuil, Diphenhist, Diphen, Unisom SleepGels, Sleep, Diphen Cough, Hydramine, Benadryl Children's Allergy, Sominex, Diphenadryl, Dicopanol, Diphedryl, Diphenydramine Quick Melt, Nytol, Buckley's Bedtime, 40 Winks, DPH, Q-Dryl, Sleep-Eze-3, Valu-Dryl, Diphenyl, Beldin, Vicks QlearQuil Nighttime Allergy Relief, Sleep-ettes, Allermax, Diphendryl, Q-Dryl A/F, Histaprin, Tranquil Nighttime Sleep Aid, Dormin, Sleepwell 2-nite, Snooze Fast, Sominex Maximum Strength Caplet, Unisom SleepMinis, Unisom Liquid, Triaminic Thin Strips Allergy, ConRx Allergy, Hyrexin, Hydramine Cough Syrup, Bydramine, Diphen AF, Aler-Dryl, Allergia-C, Benahist-10, Benahist-50, Benoject-50, Calm-Aid, Genahist, Alka-Seltzer Plus Allergy, Aller-G-Time, Sleep Tab II, Sleep Tabs, Somnicaps, Nytol QuickCaps, Total Allergy, Trux-adryl, Altaryl, Triaminic Thin Strips Cough & Runny Nose, Belix, Siladryl, Siladryl DAS, Siladyl SA, Silphen Cough, Tusstat, Diphenylin, Hydramine Compound, Pardryl, Quenalin, Nervine, Nu-Med, Nytol Caplet, Compoz Nighttime Sleep Aid, Sleepinal, Help I Can't Sleep, Twilite, Banaril, Aler-Tab, Siladryl Allergy, Theraflu Thin Strips Multi Symptom, Sleep-ettes D, Uni-Tann, Diphenmax, Nightime Sleepaid, Ben-Tann, Dytan, Vanamine PD, Pharbedryl, Z-Sleep, Unisom SleepMelts, PediaCare Children's Allergy, Truxadryl, Simply Sleep, Complete Allergy Relief, Dytuss, Miles Nervine, Scot-Tussin Allergy)
- duloxetine (Cymbalta, Irenka)
- Fish Oil (omega-3 polyunsaturated fatty acids)
- fluoxetine (Prozac, Sarafem, Prozac Weekly, Rapiflux, Selfemra)
- gabapentin (Neurontin, Gralise, Gabarone, Fanatrex)
- ibuprofen (Advil, Motrin, IBU, Proprinal, Advil Liqui-Gels, Motrin IB, IBU-200, Nuprin, Advil Infant's Concentrated Drops, Children's Motrin, Advil Children's, Ibu-8, Ibuprofen PMR, Caldolor, Motrin Childrens, Motrin Migraine Pain, Addaprin, Ibu-4, Ibu-Tab, Rufen, Midol IB, A-G Profen, Childrens Ibuprofen Berry, Advil Migraine, Ibu-6, Motrin Infant Drops, NeoProfen, Genpril, Haltran, Menadol, Saleto-200, Q-Profen, Saleto-400, Saleto-600, Saleto-800, Advil Junior Strength, Midol Maximum Strength Cramp Formula, Actiprofen, PediaCare Infants' IB Ibuprofen Pain Reliever/Fever Reducer, PediaCare Children's IB Ibuprofen Pain Reliever/Fever Reducer, Motrin Junior Strength, Help I Have An Aching Body, Children's ElixSure IB, Cap-Profen, Motrin Pediatric, Advil Film-Coated)
- Lipitor (atorvastatin)
- lorazepam (Ativan, Lorazepam Intensol)
- Lyrica (pregabalin)
- Metoprolol Succinate ER (metoprolol)
- Metoprolol Tartrate (metoprolol)
- Nexium (esomeprazole)
- Norco (acetaminophen / hydrocodone)
- phentermine (Adipex-P, Lomaira, Fastin, Ionamin, Suprenza, Teramine, Phentride, T-Diet, Obenix, Atti-Plex P, Pro-Fast HS, Phentercot, Oby-Cap, Obephen, Panshape M, Pro-Fast SR, Zantryl, Oby-Trim, Pro-Fast SA, Teramine ER)
- Plavix (clopidogrel)
- ProAir HFA (albuterol)
- propranolol (Inderal, Inderal LA, Hemangeol, InnoPran XL, Inderal XL)
- Seroquel (quetiapine)
- Synthroid (levothyroxine)
- tramadol (Ultram, Tramadol Hydrochloride ER, Tramal, Ultram ER, Tramedo, GenRx Tramadol, ConZip, Zydol, Ryzolt, Larapam SR, Tramahexal, Zamadol, Tramal SR, Tramahexal SR, Zydol XL, Rybix ODT, Rybix, Ultram ODT)
- trazodone (Desyrel, Oleptro, Desyrel Dividose)
- Tylenol (acetaminophen)
- Vitamin B12 (cyanocobalamin)
- Vitamin C (ascorbic acid)
- Vitamin D3 (cholecalciferol)
- warfarin (Coumadin, Jantoven)
- Wellbutrin (bupropion)
- Xanax (alprazolam)
- Zoloft (sertraline)
paroxetine alcohol/food Interactions
There is 1 alcohol/food interaction with paroxetine
paroxetine disease Interactions
There are 11 disease interactions with paroxetine which include:
- Depression
- Bone Fractures
- Renal Dysfunction
- Hyponatremia
- Glaucoma
- Liver Disease
- Mania
- Platelet Function
- Seizure Disorders
- Siadh
- Weight Loss
More about paroxetine
- Paroxetine Side Effects
- During Pregnancy or Breastfeeding
- Dosage Information
- Patient Tips
- Drug Images
- Compare Alternatives
- Support Group
- Pricing & Coupons
- En Español
- 1005 Reviews
- Drug class: selective serotonin reuptake inhibitors
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No information available. |
Do not stop taking any medications without consulting your healthcare provider.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
