Paroxetine Drug Interactions
A total of 935 drugs are known to interact with paroxetine.
- 224 major drug interactions
- 675 moderate drug interactions
- 36 minor drug interactions
Check for interactions with paroxetine
Common medications checked in combination with paroxetine
- Adderall (amphetamine / dextroamphetamine)
- Advair Diskus (fluticasone / salmeterol)
- alprazolam (Xanax, Alprazolam Intensol, Xanax XR, Niravam)
- amitriptyline (Elavil, Endep, Vanatrip)
- Aspirin Low Strength (aspirin)
- Calcium 600 D (calcium / vitamin d)
- Crestor (rosuvastatin)
- diazepam (Valium, Diastat, Diazepam Intensol, Diastat AcuDial, Zetran, Diastat Pediatric, Dizac, Valrelease)
- diphenhydramine (Benadryl, Banophen, Benadryl Allergy, ZzzQuil, Unisom SleepGels, Dicopanol, Sleep, Diphenhist, Sominex, Diphen, Diphenadryl, Benadryl Children's Allergy, Allermax, Diphenydramine Quick Melt, Nytol, Diphedryl, Hydramine, Diphendryl, Pharbedryl, Buckley's Bedtime, Hyrexin, Hydramine Cough Syrup, Bydramine, Diphen Cough, DPH, Allergia-C, Q-Dryl, Sleep Tabs, Quenalin, Sleep-ettes D, Q-Dryl A/F, Dytan, Vanamine PD, Sleepwell 2-nite, Snooze Fast, Sominex Maximum Strength Caplet, Unisom SleepMinis, Unisom Liquid, Triaminic Thin Strips Allergy, ConRx Allergy, 40 Winks, Diphen AF, Aler-Dryl, Benahist-10, Benahist-50, Benoject-50, Calm-Aid, Genahist, Alka-Seltzer Plus Allergy, Aller-G-Time, Sleep Tab II, Sleep-Eze-3, Somnicaps, Nytol QuickCaps, Total Allergy, Trux-adryl, Valu-Dryl, Diphenyl, Altaryl, Triaminic Thin Strips Cough & Runny Nose, Beldin, Belix, Vicks QlearQuil Nighttime Allergy Relief, Siladryl, Siladryl DAS, Siladyl SA, Silphen Cough, Sleep-ettes, Tusstat, Diphenylin, Hydramine Compound, Pardryl, Nervine, Nu-Med, Nytol Caplet, Compoz Nighttime Sleep Aid, Sleepinal, Help I Can't Sleep, Twilite, Banaril, Aler-Tab, Siladryl Allergy, Theraflu Thin Strips Multi Symptom, Uni-Tann, Diphenmax, Nightime Sleepaid, Ben-Tann, Histaprin, Z-Sleep, Tranquil Nighttime Sleep Aid, Unisom SleepMelts, PediaCare Children's Allergy, Truxadryl, Simply Sleep, Complete Allergy Relief, Dytuss, Dormin, Miles Nervine, Scot-Tussin Allergy)
- duloxetine (Cymbalta, Irenka)
- Fish Oil (omega-3 polyunsaturated fatty acids)
- fluoxetine (Prozac, Sarafem, Prozac Weekly, Rapiflux, Selfemra)
- gabapentin (Neurontin, Gralise, Gabarone, Fanatrex)
- ibuprofen (Advil, Motrin, IBU, Advil Liqui-Gels, Proprinal, Motrin IB, Children's Motrin, IBU-200, Advil Migraine, Ibu-8, Motrin Childrens, Nuprin, Motrin Migraine Pain, Ibuprofen PMR, NeoProfen, Caldolor, Advil Children's, Addaprin, Motrin Infant Drops, Advil Infant's Concentrated Drops, Rufen, Genpril, A-G Profen, Ibu-Tab, Haltran, Menadol, Midol IB, Saleto-200, Q-Profen, Saleto-400, Saleto-600, Saleto-800, Advil Junior Strength, Midol Maximum Strength Cramp Formula, Actiprofen, Childrens Ibuprofen Berry, PediaCare Infants' IB Ibuprofen Pain Reliever/Fever Reducer, Ibu-4, PediaCare Children's IB Ibuprofen Pain Reliever/Fever Reducer, Ibu-6, Motrin Junior Strength, Help I Have An Aching Body, Children's ElixSure IB, Cap-Profen, Motrin Pediatric, Advil Film-Coated)
- Lipitor (atorvastatin)
- lorazepam (Ativan, Lorazepam Intensol)
- Lyrica (pregabalin)
- Metoprolol Succinate ER (metoprolol)
- Metoprolol Tartrate (metoprolol)
- Nexium (esomeprazole)
- Norco (acetaminophen / hydrocodone)
- phentermine (Adipex-P, Lomaira, Fastin, Ionamin, Suprenza, Obenix, Atti-Plex P, Pro-Fast HS, Phentercot, Oby-Cap, Phentride, Obephen, Panshape M, Pro-Fast SR, T-Diet, Zantryl, Oby-Trim, Teramine, Pro-Fast SA, Teramine ER)
- Plavix (clopidogrel)
- ProAir HFA (albuterol)
- propranolol (Inderal, Inderal LA, Hemangeol, InnoPran XL, Inderal XL)
- Seroquel (quetiapine)
- Synthroid (levothyroxine)
- tramadol (Ultram, Tramadol Hydrochloride ER, Tramal, Ultram ER, Larapam SR, Tramedo, Ryzolt, GenRx Tramadol, ConZip, Zydol, Tramal SR, Tramahexal, Zamadol, Tramahexal SR, Zydol XL, Rybix ODT, Ultram ODT)
- trazodone (Desyrel, Oleptro, Desyrel Dividose)
- Tylenol (acetaminophen)
- Vitamin B12 (cyanocobalamin)
- Vitamin C (ascorbic acid)
- Vitamin D3 (cholecalciferol)
- warfarin (Coumadin, Jantoven)
- Wellbutrin (bupropion)
- Xanax (alprazolam)
- Zoloft (sertraline)
Paroxetine alcohol/food interactions
There is 1 alcohol/food interaction with paroxetine
Paroxetine disease interactions
There are 11 disease interactions with paroxetine which include:
- depression
- bone fractures
- renal dysfunction
- hyponatremia
- glaucoma
- liver disease
- mania
- platelet function
- seizure disorders
- SIADH
- weight loss
More about paroxetine
- Paroxetine Side Effects
- During Pregnancy or Breastfeeding
- Dosage Information
- Patient Tips
- Drug Images
- Compare Alternatives
- Support Group
- Pricing & Coupons
- En Español
- 1027 Reviews
- Drug class: selective serotonin reuptake inhibitors
- FDA Alerts (8)
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No information available. |
Do not stop taking any medications without consulting your healthcare provider.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
