Nonsteroidal anti-inflammatory agents (usually abbreviated to NSAIDs) are a group of medicines that have anti-inflammatory (reduce inflammation), analgesic (relieve pain) and antipyretic (lower temperature) effects.
Although different NSAIDs have different structures, they all work by blocking cyclo-oxygenase (COX) enzymes. There are two main types of COX enzymes: COX-1 and COX-2. Both types produce prostaglandins; however, the main function of COX-1 enzymes is to produce baseline levels of prostaglandins that activate platelets and protect the lining of the gastrointestinal tract, whereas COX-2 enzymes are responsible for releasing prostaglandins after infection or injury. Prostaglandins have a number of different effects, one of which is to regulate inflammation.
Most NSAIDs inhibit both enzymes, although a few are available that mainly inhibit COX-2. The pain-relieving and anti-inflammatory effects of NSAIDs are mainly due to inhibition of COX-2, and their unwanted side effects are largely due to inhibition of COX-1.
Drug Name  ( View by: Brand | Generic )
|
Reviews |
Ratings |
Advil Children's (Pro, More...)
generic name: ibuprofen
|
0 reviews | | 10 |
Flanax Pain Reliever (More...)
generic name: naproxen
|
1 review | | 10 |
Motrin Infant Drops (More...)
generic name: ibuprofen
|
1 review | | 10 |
Children's Motrin (More...)
generic name: ibuprofen
|
3 reviews | | 9.8 |
Clinoril (Pro, More...)
generic name: sulindac
|
4 reviews | | 9.2 |
Orudis (Pro, More...)
generic name: ketoprofen
|
2 reviews | | 9.2 |
Motrin IB (Pro, More...)
generic name: ibuprofen
|
4 reviews | | 9.0 |
Orudis KT (More...)
generic name: ketoprofen
|
4 reviews | | 9.0 |
Oruvail (Pro, More...)
generic name: ketoprofen
|
1 review | | 9.0 |
Tolectin DS (More...)
generic name: tolmetin
|
1 review | | 9.0 |
Cambia (Pro, More...)
generic name: diclofenac
|
24 reviews | | 8.6 |
Lodine XL (More...)
generic name: etodolac
|
0 reviews | | 8.5 |
Nalfon (Pro, More...)
generic name: fenoprofen
|
1 review | | 8.5 |
Advil Liqui-Gels (Pro, More...)
generic name: ibuprofen
|
10 reviews | | 8.3 |
Arthrotec (Pro, More...)
generic name: diclofenac/misoprostol
|
36 reviews | | 8.3 |
Cataflam (Pro, More...)
generic name: diclofenac
|
31 reviews | | 8.3 |
Ansaid (Pro, More...)
generic name: flurbiprofen
|
3 reviews | | 8.2 |
Feldene (Pro, More...)
generic name: piroxicam
|
11 reviews | | 8.2 |
Zorvolex (Pro, More...)
generic name: diclofenac
|
15 reviews | | 8.2 |
Ibu-8 (More...)
generic name: ibuprofen
|
0 reviews | | 8.0 |
Lodine (Pro, More...)
generic name: etodolac
|
12 reviews | | 8.0 |
Nuprin (More...)
generic name: ibuprofen
|
0 reviews | | 8.0 |
Sprix (Pro, More...)
generic name: ketorolac
|
11 reviews | | 8.0 |
Naprelan (Pro, More...)
generic name: naproxen
|
14 reviews | | 7.9 |
Vimovo (Pro, More...)
generic name: esomeprazole/naproxen
|
21 reviews | | 7.9 |
Voltaren (Pro, More...)
generic name: diclofenac
|
116 reviews | | 7.9 |
Indocin (Pro, More...)
generic name: indomethacin
|
24 reviews | | 7.8 |
Indocin SR (Pro, More...)
generic name: indomethacin
|
7 reviews | | 7.4 |
Toradol IV / IM (More...)
generic name: ketorolac
|
10 reviews | | 7.4 |
Voltaren-XR (Pro, More...)
generic name: diclofenac
|
4 reviews | | 7.4 |
Naprosyn (Pro, More...)
generic name: naproxen
|
30 reviews | | 7.3 |
Toradol (Pro, More...)
generic name: ketorolac
|
152 reviews | | 7.3 |
Zipsor (Pro, More...)
generic name: diclofenac
|
30 reviews | | 7.3 |
Motrin (Pro, More...)
generic name: ibuprofen
|
14 reviews | | 7.2 |
Relafen (Pro, More...)
generic name: nabumetone
|
30 reviews | | 7.1 |
Anaprox-DS (More...)
generic name: naproxen
|
5 reviews | | 7.0 |
EC-Naprosyn (More...)
generic name: naproxen
|
0 reviews | | 7.0 |
Ibu-6 (More...)
generic name: ibuprofen
|
0 reviews | | 7.0 |
Aleve (More...)
generic name: naproxen
|
87 reviews | | 6.9 |
IBU (Pro, More...)
generic name: ibuprofen
|
0 reviews | | 6.9 |
Mobic (Pro, More...)
generic name: meloxicam
|
114 reviews | | 6.9 |
Ponstel (Pro, More...)
generic name: mefenamic acid
|
15 reviews | | 6.9 |
Advil (Pro, More...)
generic name: ibuprofen
|
21 reviews | | 6.7 |
Anaprox (More...)
generic name: naproxen
|
7 reviews | | 6.7 |
Duexis (Pro, More...)
generic name: famotidine/ibuprofen
|
14 reviews | | 6.6 |
Midol Extended Relief (More...)
generic name: naproxen
|
1 review | | 6.3 |
Daypro (Pro, More...)
generic name: oxaprozin
|
4 reviews | | 6.2 |
IBU-200 (More...)
generic name: ibuprofen
|
0 reviews | | 5.5 |
Dolobid (Pro, More...)
generic name: diflunisal
|
4 reviews | | 5.2 |
All Day Pain Relief (More...)
generic name: naproxen
|
0 reviews | | 4.5 |
Advil Migraine (More...)
generic name: ibuprofen
|
1 review | | 3.7 |
Indocin IV (More...)
generic name: indomethacin
|
1 review | | 2.0 |
A-G Profen (More...)
generic name: ibuprofen
|
0 reviews | | 0.0 |
Actiprofen (More...)
generic name: ibuprofen
|
0 reviews | | 0.0 |
Addaprin (More...)
generic name: ibuprofen
|
0 reviews | | 0.0 |
Advil Infant's Concentrated Drops (Pro, More...)
generic name: ibuprofen
|
0 reviews | | 0.0 |
Aflaxen (More...)
generic name: naproxen
|
0 reviews | | 0.0 |
All Day Relief (More...)
generic name: naproxen
|
0 reviews | | 0.0 |
Caldolor (Pro, More...)
generic name: ibuprofen
|
0 reviews | | 0.0 |
Dyloject (More...)
generic name: diclofenac
|
0 reviews | | 0.0 |
Fenortho (More...)
generic name: fenoprofen
|
0 reviews | | 0.0 |
Genpril (More...)
generic name: ibuprofen
|
0 reviews | | 0.0 |
Haltran (More...)
generic name: ibuprofen
|
0 reviews | | 0.0 |
Ibu-4 (More...)
generic name: ibuprofen
|
0 reviews | | 0.0 |
Ibu-Tab (More...)
generic name: ibuprofen
|
0 reviews | | 0.0 |
Midol IB (More...)
generic name: ibuprofen
|
0 reviews | | 0.0 |
Motrin Childrens (More...)
generic name: ibuprofen
|
0 reviews | | 0.0 |
Motrin Junior Strength (More...)
generic name: ibuprofen
|
0 reviews | | 0.0 |
NeoProfen (Pro, More...)
generic name: ibuprofen
|
0 reviews | | 0.0 |
Prevacid NapraPAC (Pro, More...)
generic name: lansoprazole/naproxen
|
0 reviews | | 0.0 |
Proprinal (More...)
generic name: ibuprofen
|
0 reviews | | 0.0 |
Q-Profen (More...)
generic name: ibuprofen
|
0 reviews | | 0.0 |
Tivorbex (Pro, More...)
generic name: indomethacin
|
0 reviews | | 0.0 |
Tolectin (Pro, More...)
generic name: tolmetin
|
0 reviews | | 0.0 |
Tolectin 600 (More...)
generic name: tolmetin
|
0 reviews | | 0.0 |
