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Fludrocortisone Dosage

Medically reviewed by Last updated on Dec 5, 2022.

Applies to the following strengths: 0.1 mg

Usual Adult Dose for Addison's Disease

0.1 mg orally per day
Maintenance dose: 0.1 mg orally 3 times a week to 0.2 mg orally per day


  • If transient hypertension occurs as a consequence of therapy, dose should be reduced to 0.05 mg per day
  • Often given concomitantly with cortisone or hydrocortisone.

Use: For partial replacement therapy for primary and secondary adrenocortical insufficiency in Addison's disease

Usual Adult Dose for Adrenogenital Syndrome

0.1 to 0.2 mg orally per day

Use: For the treatment of salt-losing adrenogenital syndrome

Renal Dose Adjustments

Use with caution.

Liver Dose Adjustments

Use with caution.



  • Hypersensitivity to the active component or to any of the ingredients
  • Systemic fungal infections

Safety and efficacy have not been established in patients younger than 18 years.

Consult WARNINGS section for additional precautions.


Data not available

Other Comments

Administration advice:

  • Doses are dependent upon severity of the disease and response of individual patients.
  • Continually monitor patients for signs that indicate dose adjustment may be necessary, including remission or exacerbations of disease and stress (surgery, infection, trauma).
  • If a dose is missed, take it as soon as it is remembered unless it is almost time for the next dose; doses should not be doubled.

Storage requirements:
  • Avoid excessive heat.
  • Dispense in a tightly closed, light-resistant container.

  • Cardiovascular: Monitor blood pressure regularly.
  • Metabolic: Monitor serum electrolytes regularly.

Patient advice:
  • Report any medical history of heart disease, high blood pressure, or kidney or liver disease and current use of any medicines.
  • Avoid exposure to chicken pox or measles if on immunosuppressant doses.
  • Carry an adequate supply of medication for use in emergencies.
  • Notify your physician of dizziness, severe or continuing headaches, swelling of feet or lower legs, or unusual weight gain.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.