Fludrocortisone Alternatives Compared
| Fludrocortisone | Midodrine | Florinef |
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| Fludrocortisone | Midodrine | Florinef (fludrocortisone) |
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Prescription only
Prescribed for Addison's Disease, Adrenogenital Syndrome. May also be prescribed off label for Postural Orthostatic Tachycardia Syndrome, Dysautonomia. |
Prescription only
Prescribed for Hypotension. May also be prescribed off label for Postural Orthostatic Tachycardia Syndrome, Dysautonomia. |
Prescription only
Prescribed for Addison's Disease, Adrenogenital Syndrome. May also be prescribed off label for Postural Orthostatic Tachycardia Syndrome, Dysautonomia. |
Related suggestions Postural Orthostatic Tachycardia Syndrome
Dysautonomia
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| More about Fludrocortisone | More about Midodrine | More about (fludrocortisone) | ||||||||||||||||
| Generic Status | ||||||||||||||||||
| Ratings & Reviews | ||||||||||||||||||
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Fludrocortisone has an average rating of 7.5 out of 10 from a total of 40 ratings on Drugs.com. 59% of reviewers reported a positive effect, while 18% reported a negative effect. |
Midodrine has an average rating of 6.2 out of 10 from a total of 39 ratings on Drugs.com. 57% of reviewers reported a positive effect, while 35% reported a negative effect. |
Florinef has an average rating of 8.5 out of 10 from a total of 6 ratings on Drugs.com. 67% of reviewers reported a positive effect, while 0% reported a negative effect. |
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| Drug Class | ||||||||||||||||||
| Side Effects | ||||||||||||||||||
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See also: fludrocortisone side effects in more detail. |
Commonly reported side effects include:
See also: midodrine side effects in more detail. |
See also: Florinef side effects in more detail. |
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| Pricing and Coupons * Prices are without insurance | ||||||||||||||||||
View all fludrocortisone prices |
View all midodrine prices |
We could not find an exact match for this medicine. Try searching the Price Guide directly. |
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| Dosage Form(s) Available | ||||||||||||||||||
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N/A |
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| Brand Names | ||||||||||||||||||
| Florinef, Florinef Acetate | Orvaten | Other fludrocortisone brands include: Florinef Acetate | ||||||||||||||||
| Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | ||||||||||||||||||
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36 hours |
4 hours |
36 hours |
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| CSA Schedule ** View glossary of terms | ||||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | ||||||||||||||||||
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | ||||||||||||||||||
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A total of 532 drugs are known to interact with fludrocortisone:
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A total of 163 drugs are known to interact with midodrine:
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A total of 532 drugs are known to interact with Florinef:
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| Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | ||||||||||||||||||
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| First Approval Date | ||||||||||||||||||
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August 18, 1955 |
September 06, 1996 |
N/A |
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| WADA Class View World Anti-Doping Agency classifications. | ||||||||||||||||||
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N/A |
N/A |
N/A |
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| More Information | ||||||||||||||||||
| Patient resources | ||||||||||||||||||
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N/A |
N/A |
N/A |
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| Professional Resources | ||||||||||||||||||
| Related Treatment Guide | ||||||||||||||||||
** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.