Skip to Content

User Reviews for Wellbutrin

Condition Avg. Rating Reviews Compare
Depression  
7.0
479 reviews 78 medications
Major Depressive Disorder  
6.8
111 reviews 47 medications

Reviews may be moderated or edited before publication to correct grammar and spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest in the medication will not be published. As reviews and ratings are subjective and self-reported, this information should not be used as the basis for any statistical analysis or scientific studies.

Reviews for Wellbutrin

Nathalie21 June 6, 2021

For Depression: “Just starting this med. The first couple days, I didn’t think it was doing much, but I noticed I couldn’t sleep for very long. I wasn’t as hopelessly sad as I had been the week prior, but I was experiencing an array of stomach-related side effects (constipated until I was very much no longer constipated, bloating, stomach aches, & VERY nauseous the first night). Fast forward a few days, I still can’t sleep very much. I’m artificially active is the best way to describe it. I’ve been pretty inactive throughout the pandemic, but I walked to get iced coffee in 90 degree heat, cleaned my apartment, had people over, then went to the gym later because I was so jittery and couldn’t sit still. It also has given me quite a bit of anxiety and some irritability alongside the constant need to be active. I hope that over the next few days, the anxious thoughts, stomach issues, & insomnia calm down.”

8 / 10
Was this helpful?YesNo
Claire · Taken for less than 1 month May 1, 2021

For Depression: “I’m that patient that smokes you know what... My doctor knows. This time around being 20 now and taking this pill again, I’m on day 4 or 5 and my appetite is absolutely gone even when elevated. But I think I’m feeling more balanced out overall, but when I have my anxiety moments, they are very intense. Too soon to tell if I could recommend it, but it has interacted fine with maryJ past 4-ish days:”

6 / 10
Was this helpful?YesNo
Courtney R · Taken for 1 to 6 months April 23, 2021

For Depression: “Background: depression, anxiety, intrusive thoughts, seasonal depression I went with Wellbutrin because it had the least side effects compared to most depression medications and it was recommended by many people. I must say it really has been life changing. When I started Wellbutrin it made me think much clearer. While I still do get thoughts, they are not intrusive. My mood is stable and I feel generally happy! Week 1- sensitivity to caffeine, racing heart for one day, increased energy, appetite decreased Week 2- energy balanced out, appetite low Week 3- appetite back, energy consistent, mood improving, felt happy and no intrusive thoughts Week 4- I feel great! I do sometimes experience ringing in my ear, but nothing that is bothersome. Overall, this medication has saved me. I recommend taking this medication while seeing your therapist. Both of them together have really pushed me in the right direction.”

10 / 10
Was this helpful?YesNo

Frequently asked questions

alive13 · Taken for 2 to 5 years March 20, 2021

For Major Depressive Disorder: “Like others on this site, I have tried so many antidepressants. SSRIs take away any sexual feeling for me, and I tend to put on weight and not have the best self image with them. Buproprion is the only medication that really allows me to FEEL my feelings, and talk more easily in social settings. After your adjust (some insomnia for a few weeks) it actually helped me to sleep better. It took me a few times of trying this medication to really get it to work for me. It helped with my anxiety rather than making it worse, but depression was my biggest problem, hopelessness, fatigue etc. This medication makes jokes funny, trees prettier and makes me feel emotionally stronger. Remember that it takes courage and patience to get help and to stick with it until it works. God bless.”

10 / 10
Was this helpful?YesNo
Andi · Taken for 6 months to 1 year July 31, 2020

For Major Depressive Disorder: “GIVE THIS MEDICATION WELLBUTRIN A FIGHTING CHANCE I almost quit a month in, but I am SO glad I didn’t and toughed out the negative side effects. When I started I felt dazed and sedated, but wired and jittery at the same time. My insomnia was horrible. Other side effects I experienced included tinnitus, horrible anxiety, hand tremors, heart palpitations, and a really short temper. I desired nothing, but had the energy to do everything - weird combo. OKAY, now for the GOOD, and things I think people should know before giving up this medication - the side effects last a LONG time (two and a half months for me), but they DO all go away. I was now able to get up early to workout, got into cooking, lost weight, and felt hopeful about life. Sex also got WAY better now that I could stop living in my head, which was a huge plus. For the first time in a long time I can really say I feel happy. So give it time!”

8 / 10
Was this helpful?YesNo
F/21 June 14, 2020

For Major Depressive Disorder: “This drug Wellbutrin has been life changing for me. After trying SSRIs and SNRIs that didn’t work, it did the trick. Yes, it sucks at first; the side effects are horrible but you have to give it time. And on these meds at first, I got the head zaps, anxiety like I had never felt before, heart palpitations, lack of appetite and weight loss, headaches, nausea, severe insomnia- the whole nine yards. But after about 5 months on 300 mg, I turned a corner and feel better than ever. I can focus, I’m not tired but can sleep if I need to, my anxiety largely went away, I’m happy and can orgasm too. All the side effects pretty much subsided, save for the appetite one... I still don’t have to eat if I don’t want to but I’m not repulsed by the idea of food anymore. So seriously, it isn’t a conventional drug and it’s bad initially but PLEASE stick with it. Don’t expect it to work overnight... these things take time. I promise you will get results. You got this. Hang in there!”

10 / 10
Was this helpful?YesNo
Cancer2Depression September 5, 2020

For Depression: “I was a 250 pound fat and happy married man until I was diagnosed with stage 3B cancer. My wife and kids convinced me to see a Psych and get treated. Anyway, he started my on Wellbutrin (BUPROPION generic) at 200mg per day. He said this med has been around a long time and it's very safe and effective. Note that I don't have Anxiety. After a week on BUPROPION, I would sing on the way to work and was unable to take the smile off my face. After about 6 months these feelings wore off, but I was still better than before. My Psych upped the dosage to 300mg per day. I take two 100mg pills at 9am and then one 100mg pill at 230pm. Overall, I'm happy. It worked for me. Only side effects are a little insomnia twice per month and ringing in my ears 4 times per month, which lasts for hours each time. The ringing is very low. I get my meds Generic for a 90 day supply each time and my insurance charges me $24 for that 90 day supply (300mg/day).”

9 / 10
Was this helpful?YesNo

More FAQ

TheTwizler · Taken for less than 1 month June 1, 2020

For Depression: “I'm on day 3 of wellbutrin. So far it's been miserable. I'm on the lowest dose and still having horrible stomach side effects. I can't eat, I have no appetite, severe diarrhea with intense stomach pain. I'm also exhausted but can't seem to sleep more than a few hours at a time. My mouth is dry and my eyeballs feel like sandpaper. And to top it all off, just looking at my husband arouses me. I'd actually enjoy that side effect if I could stay off the toilet. I'm gonna try to stick it out in hopes that this will pass. I know I need to give it some time.”

Was this helpful?YesNo
Kai2277 October 10, 2018

For Depression: “I had an odd situation where I was not really depressed with sadness but I just felt nothing. I never got angry, never got happy- never wanted to do anything besides lay in bed. I tried to fake it as much as possible but I couldn’t anymore. I stopped answering my phone, lost all interest and motivation. I had taken all the antidepressants on the market but they made me feel crazy. My hands shook and I felt out of my body. I started researching the symptoms of low dopamine and I had almost all of the symptoms- poor memory, poor concentration, excessive worrying, lack of motivation- and overall just not giving a $#|+ about anything. I asked my doctor for Wellbutrin. In a couple of days I was calling old friends, kicking butt at work, and motivated for life again. My problem all along was dopamine not serotonin. I am thankful I figured it out. DON'T GIVE UP. Read about brain chemicals- dopamine, serotonin, and, norephenephrine- and make the choice based on research.”

10 / 10
Was this helpful?YesNo
rasinsomniac · Taken for less than 1 month May 27, 2020

For Depression: “After a break up with my girlfriend and one true love of my life I went to a really dark place and had serious suicidal thoughts. I was first put on Brintellix, then Valdoxan and three weeks ago to Wellbutrin. It's been six months since the break up and after using this med for 3 weeks I'm finally able to enjoy life again and have energy to get through the days with pleasure. This med has so far been a life safer for me. First two weeks were hard and I had serious insomnia but now for the first time in 6 months I don't need Ambien to sleep anymore. I seriously recommend this med, at least for me its working perfectly so far. Just give it time to start working and you will feel better.”

10 / 10
Was this helpful?YesNo
Woody October 2, 2020

For Depression: “I began Bupropion about a year ago. Took a while to kick in, Waiting eight weeks for the hoped-for effect was like waiting eight months. I had tried another med and it left me with negative sexual side effects which is why the doctor suggested Bupropion. I've been taking low dose Viagra, honestly don't know if I need it . . . but Viagra works. I told my doctor that I'm okay, but don't seem to feel any drastic change from when I first began the med. She suggested upping to 300 mg extended release. After a week I began to feel better but, don't know if it is from the med or the high of knowing I made the attempt at trying to feel better. Wishful thinking is a good way to put it. So here's my question: Since I was already taking Bupropion at 150 mg/day extended release should I expect the new dosage of 300 mg to take eight weeks to fully kick in? Has anyone had this experience?”

9 / 10
Was this helpful?YesNo
struggler79 January 17, 2015

For Depression: “I am a 35 year old woman, who has taken meds for 1/2 her life. I struggle with obsessive compulsive disorder, intrusive thoughts and overall depression. Wellbutrin.. I take 150mg a day. It has changed my life.. I have less obsessive thinking, more motivation and for some reason care way less about what people think.”

9 / 10
Was this helpful?YesNo
Salim April 26, 2020

For Major Depressive Disorder: “Wellbutrin was amazing to me I was on it for depression, but I stopped smoking after I used to smoke a lot a day. It gave me enormous energy and improved my depression a lot. I am thankful to the scientists who developed this drug. Don't let the negative reviews scare you. Try it and you will not regret it”

10 / 10
Was this helpful?YesNo
Leigh · Taken for 1 to 6 months January 2, 2021

For Depression: “When I tried an SSRI I ended up lying on the floor almost unresponsive. I won't take one again. In the last year my depression and anxiety got really bad. Horrible panic attacks, slamming doors, screaming, irritability... then came the suicidal thoughts. My doctor suggested Wellbutrin. I have a very sensitive body so I started on 75 mg once a day. Man. I noticed a difference within the first day or two. The third day I woke up with tons of energy and unpacked my suitcase that had been sitting in my closet for a week, before I even started working! Unheard of for me. My outlook on life has improved, I don't snap at my husband, I don't get annoyed. Plus I've lost 4 lbs and my sex drive has increased slightly. The only side effects I've had were the brain "zingers" people talk about (they have subsided) and pretty bad insomnia. I'm hoping the insomnia goes away, but right now the positives definitely outweigh the negatives! A world of difference!”

9 / 10
Was this helpful?YesNo
Pr23 December 23, 2019

For Depression: “Okay, I came back to rate again. It has now been about a little over a month on Wellbutrin and wow it has saved my life. It was like a total switch in the way I think and feel everyday! For years and years I’ve been depressed but this year was so bad,I didn’t care about myself. I was also so unmotivated.. crying multiple times a day even while at work.. I’d be triggered by anything and start having anxiety attacks. Now, I can finally say I am happy with my life! It’s like I can see my life clearly now, it’s no longer a fog, I don’t obsess over all the negative things... I have energy to go to the gym often and eat right and I’ve lost over ten pounds. I have goals again and I have my self confidence back.I t feels unreal I did miss a few pills every other day for about a week and a half and I felt a difference, I cried once and I was also binge eating. But I went back to normal once I went back to taking all my pills on time.”

10 / 10
Was this helpful?YesNo
Anonymous March 30, 2021

For Depression: “Saved my life and marriage after I had severe PPD and PPA. I would still have some bad anxiety every once in a while but overall totally worth it. I also found that Benadryl really helps if you have anxiety with this at night. I was able to gain the confidence to start my own business and actually believe for the first time in my life I could truly accomplish something. I pray this med helps others like it’s helped me.”

10 / 10
Was this helpful?YesNo
jkn1416 January 1, 2015

For Depression: “Before starting Wellbutrin I was so depressed, crying all the time, no motivation, no energy, no ability to make decisions or follow through with them, no desire to go anywhere. I've been taking Wellbutrin for about 3 weeks and within a 5 days I was noticing a difference. The crying has stopped, I'm more motivated, I have more energy and I'm making decisions I couldn't before. I have been active, forcing myself to go to the gym but now I'm more eager to go. Wellbutrin has made a huge difference for me.”

9 / 10
Was this helpful?YesNo
AB · Taken for 2 to 5 years August 17, 2020

For Depression: “I had Bipolar Disorder with depression and psychotic symptoms. I was put on Ability 15mg but I got Tardive Dyskinesia. The dosage was lowered to 10mg and then 5mg. I stopped with the psychotic symptoms immediately. But I was still depressed and not enjoying my life. So they added 150 mg Extended Release Wellbutrin and I got much better. I felt a little nauseous when I first started taking it but that stopped a few months into treatment. I still was requiring daily 1 to 2 hour naps to get through my day. Then my medicine was increased to Wellbutrin 150MG SR two times a day. Finally I felt like myself again. I had energy and felt like I could take on all my responsibilities again. It worked beautifully with Abilify for me. Hope it works for you!”

10 / 10
Was this helpful?YesNo
ZT March 12, 2014

For Depression: “Five months after my Daughters fatal car accident, my Dr. suggested Celexa for my depression. I took it for 6 months. It made me worse, my Dr. thought that Wellbutrin might be better. It has really helped, just after 3 weeks I've noticed a big difference in my life. I take 200mg per day and now I can finally get on with my life knowing that some day we will be together.”

9 / 10
Was this helpful?YesNo
Anonymous October 25, 2014

For Depression: “I am not a proponent of Big Pharma, and have always had to try to "deal" with my problems on my own. I have a really excellent diet, exercise, don't smoke, eat an organic diet - I'm just saying I really take care of myself. I have had anxiety (with a little bit of depression) all of my life. I was diagnosed with PTSD a few years ago, as I was having severe anxiety about being accepted into nursing school, and if I would be able to handle to stress and constant pressure, and I also have concentration problems. I have been off and on SSRIs, which have been nothing but terrible for me...Paxil, Zoloft, & Prozac, of which made me feel like a zombie. Wellbutrin is GOLD. Not tired, less irritable, not panicky. It has changed my life.”

10 / 10
Was this helpful?YesNo
Hannah · Taken for less than 1 month December 8, 2019

For Depression: “Best medication I’ve ever taken. I didn’t realize how depressed I was before taking it. Now I have energy to get through the day. It also helped with my obsessive thoughts. I’ve never felt so much relief in my life. The only side effect is a slightly dry mouth but I’d take that any day over the hell I was living in.”

10 / 10
Was this helpful?YesNo
KB80 October 6, 2014

For Depression: “Well I am very pleased to tell you that I started Wellbutrin XL 150mg for depression and anxiety and I can honestly say that it is a miracle drug! I started feeling much better after just one day, I could not believe it. It has been 30 days now and I have not had even one side effect. My depression went away almost right away and the anxiety took a couple weeks. But 30 days later I feel completely myself again. This medication is definitely doing its job 100%.”

10 / 10
Was this helpful?YesNo
ASDFG · Taken for 5 to 10 years August 22, 2020

For Major Depressive Disorder: “This Wellbutrin is the only antidepressant I can tolerate. It seems to be one of the more stimulating ones, which I need because of my hypothyroidism. I can't handle a high dose so have stuck with 100-150mg 1x a day for over 5 years and I don't usually feel depressed. If I miss a dose I feel a little down and lethargic. I've smoked on and off for 20+ years and I can't say it helps me in that area--at least not at the dose I'm taking. I've been told I am wired differently than most (O-) and so far this is the only mostly effective antidepressant I have ever taken without side effects.”

9 / 10
Was this helpful?YesNo
Joy · Taken for 1 to 6 months September 2, 2020

For Major Depressive Disorder: “I’m 39 female that was prescribed Wellbutrin/Bupropion without a psych evaluation and soon as I started taking it... I began having dreams and sexual desires. I continued thinking things would change but they got worse. Weeks later I began to hallucinate and even forgot where I parked my car after going shopping one day and ended up calling police and reported it stolen when it wasn’t. I also started seeing things that weren’t there and having really dark thoughts. This drug took over my life and caused me to make irrational decisions like up and moving 1200 miles across country for no apparent reason whatsoever. A situation I regret! I got a second opinion and was taken off of wellbutrin immediately and given a psych evaluation. I was given prozac and trazadone but no longer take them. I just got a puppy, I changed my diet and lifestyle and learned coping mechanisms. I will never take another pill if I can help it.”

1 / 10
Was this helpful?YesNo
Shy Cab February 5, 2021

For Depression: “I started taking 100mg of Wellbutrin 2 months ago. I was prescribed it for ADHD but I also suffer from severe depression. The first four days of this drug were absolutely awful, I cried and felt an extreme hopelessness. After the second week the sadness was fading but I felt numb, the only positive thing is that it has decreased my irritability HEAVILY like I used to snap at so many small things and now I am unbothered but this has been replaced with sensitivity and getting emotional/crying easily. Also has helped with my sex drive. It hasn’t helped for my ADHD, I also no longer have an appetite. Two days ago I was bumped up to 300mg a day and the first day taking it I went back into the same despair I felt, but the suicidal thoughts were worse this time but luckily my boyfriend was there. I’m not sure if this is worth taking in the long run but I’d rather be more emotional then have the irritability come back. Wishing everyone suffering from depression lots of love:)”

6 / 10
Was this helpful?YesNo
sad panda no more · Taken for 1 to 6 months January 22, 2019

For Depression: “Wow. What an amazing drug. I have been on cymbalta for about 5 years, it was a life saver after a really bad period but began to lose its effectiveness. My doctor added wellbutrin 200mg and I feel like my old self again. Lots of energy, no feeling like the day is to hard to attack. No more feelings about giving up. No need for my daily nap. Wish I would have tried it 20 years ago could have saved a lot of needless pain. I am 40 now and have only been treated for depression for the last 5 years. If anyone out there feels sad all the time for no reason go to your doctor, it doesn't have to be that way. Anyway loving wellbutrin.”

10 / 10
Was this helpful?YesNo
Dee · Taken for 6 months to 1 year December 15, 2019

For Depression: “I have suffered with anxiety and depression since I was around 16 years old..I am 32 now and I have tried many different antidepressants none of which really helped until I was put on wellbutrin about a year ago. It took a little while of me taking it before I really noticed a difference, but I stuck with it and I am so happy I did. I have completely given up smoking cigarettes (have been smoking regularly since 18) and it has saved my marriage...my mood has changed completely! I feel so thankful for life now and I look forward to the future. Wellbutrin saved my life.”

10 / 10
Was this helpful?YesNo
Vice February 13, 2020

For Major Depressive Disorder: “Wellbutrin has changed my life ! I was such a terrible and irrational and very depressed person before this medication. My partner and I was always arguing at mostly the fault of my own. I had such a hard time getting out of bed and taking on the day. I would absolutely need a mid afternoon four hour nap to get me through. Wellbutrin has given me so much mental clarity. It has saved my relationship. And it’s allowed me to go through my days feeling “normal”. The only downfall is it gives me a very dry mouth which is not good for my overall oral health but I have found some toothpaste and mouthwash that help a little. It’s worth it for the clear mind.”

9 / 10
Was this helpful?YesNo

This information is NOT intended to endorse any particular medication. While these reviews might be helpful, they are not a substitute for the expertise, knowledge and judgement of healthcare practitioners.