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Wellbutrin User Reviews & Ratings (Page 5)

Wellbutrin has an average rating of 6.8 out of 10 from a total of 756 reviews on Drugs.com. 58% of reviewers reported a positive experience, while 23% reported a negative experience.

Reviews for Wellbutrin

Commonly mentioned side effects
  • Mik...
  • January 22, 2020

For Major Depressive Disorder "Stopped taking Suboxone for opiate addiction and Wellbutrin saved my life. Only thing I use that I should’ve looked into years ago for my depression, anxiety, and slight ADHD! Highly recommend it to opiate users coming off blockers or meds. Side effects: insomnia for the first week, and dry mouth. Otherwise, I’m a big placebo guy but I noticed an instant change in mood (for the better)!"

10 / 10
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  • AKT...
  • September 2, 2013

For Depression "The first time I took Wellbutrin I was in the hospital for major depression, suicidal ideation, and a nervous breakdown. After trying the typical Zoloft, Paxil, and others, the doctors were running out of options. A new doctor on staff gave me Wellbutrin (I don't remember the dose) and I instantly was transported to a state I can only describe as ecstasy. Unfortunately, this lasted only one day, probably because of my 'virgin' brain. But staying on this med for two years helped me recover my life. I am so grateful. This was 15 years ago, and although I still suffer from major depressive disorder, I have been able to get a Master's degree and a new career."

5 / 10
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165 Report
  • Anonymous
  • Taken for 6 months to 1 year
  • July 1, 2017

For Depression "This drug has saved my life! I have struggled with methamphetamine addiction for about 4 years now. The hardest part about quitting was the extreme depression and suicidal thoughts. They always caused me to relapse. My physician prescribed Wellbutrin and it has worked like a miracle. I have been clean for over half a year and feel like I have my old life back! My relationships are healing and my family feels like they have their son/brother back. I am back in college and passing my classes! I don't attribute all that to the drug. Counseling and AA were extremely helpful but I know it was Wellbutrin that got me through the horrible depression to the other side. Only upfront side effects I had were jitteriness and dry mouth."

9 / 10
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112 Report

Frequently asked questions

  • Anonymous
  • July 23, 2008

For Depression "I have been taking Wellbutrin for almost a month now and I have already noticed a change. I used to be this really upbeat, happy, positive person, and all of a sudden, I was tired all the time, couldn't sleep, was really sad all the time, agitated really easily, and also got snippy with people at the drop of a hat. My mom was the one who said I needed to go see the doctor and find out what was going on with me. I've tried other antidepressants, this is the only one that works for me."

10 / 10
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  • hso...
  • April 24, 2016

For Depression "Probably saved my life. This is the first antidepressant I tried as I was scared of some of the nasty side effects of the SSRIs (sexual, weight gain, tiredness). I was on Wellbutrin XL 150 mg for 1-2 months and then have been on 300 mg XL for 3 months now. Getting on it was a little strange, as I had some side effects of anxiety at first, but actually have not had a panic attack since starting. Just know that it doesn't really help with anxiety/OCD symptoms (but I've been going to therapy for that). Really made me motivated to get work done (never been the case for me) without that craziness feeling from Adderall. Very consistently good mood and makes me want to be alive. Also increased sex drive + motivation for exercise is a plus."

8 / 10
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124 Report

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  • smw...
  • Taken for 5 to 10 years
  • July 20, 2012

For Depression "I'm 33 years old. I've been on this medication for 6 years. My mood, temper, and life in general are so much better. I went several years with depression that came on with postpartum. In a state of denial about my condition and not wanting to be labeled, I would not seek treatment. I wish I would have done so much sooner. I cannot say enough about Wellbutrin, it has changed my life. I deal with stress, death, and everyday life of raising two teenagers now, which I firmly believe I could not have done without it. I have found you can be happy and would encourage people to get the mental help they need because medications like this one are life-changing. I can also add side effects have not been an issue for me at all."

10 / 10
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  • Kri...
  • Taken for 6 months to 1 year
  • February 28, 2025

For Major Depressive Disorder "This is the most amazing medication I've ever taken. I've had issues with alcohol, and I'm on day 3 after increasing my dose, and I had zero cravings for alcohol today, which is crazy. I am also way more motivated and getting so much done at work. Before, I felt like I just wanted to sleep all day long. I was so negative every day, cried all the time, genuinely hated the idea of having to live another day. I can't even believe the change in myself in just a matter of days. I feel happy again and have a lot of energy. For anyone wanting to try this, I absolutely recommend it, it's life-changing!!"

10 / 10
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More FAQ

  • som...
  • Taken for less than 1 month
  • June 17, 2023

For Depression "I started bupropion 75 mg and was on it for 10 days. The first days, I was agitated and hypervigilant, had problems with driving as everything attracted my attention, and felt a bit more active. I became careless and a bit arrogant. My empathy and people-pleasing behaviors lowered. I could socialize, not feeling inferior. Slowly, the medicine lost effect. The next 10 days were bupropion ER 150 mg. It gave me grave depression, I feel like I am in a cage, extreme depression, and I feel people are all monsters. I still have empathy, but no joy, no happiness, nothing. I can study, and my brain fog is gone. I can focus if I eat something. Now I am on 300 mg bupropion ER. Still very depressed. No joy. My kidneys are starting to hurt, and I have some breathing problems and nasal dripping problems. Super aware of my surroundings, studying is easy. I have lost joy, and I sleep all the time. I have a dull headache. I feel like if I continue, I will have a mental episode."

1 / 10
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  • Lif...
  • Taken for less than 1 month
  • February 27, 2025

For Depression "Before I started taking Wellbutrin, I was very tired, stressed, had difficulty concentrating, sad, and unmotivated. Within a week of being on 150 mg a day, I felt such a tremendous positive change. I sleep better too. Now I am actually looking forward to the rest of my life instead of dreading it. I feel inspired, more disciplined, and my mood is stable. I hope this medication continues to support me as a method in my toolbox to improve the quality of my life."

10 / 10
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  • Ddd...
  • Taken for 1 to 6 months
  • February 29, 2020

"Aside from the minor headaches and nausea, my experience has been better than most of the recent reviews. I started on Lexapro several years ago, but the sexual side effects were just too much for me compared to the minor effect it had on my well-being. I've had none of that with Wellbutrin, and I feel much better. I've lost approximately 35 lbs since starting, though I've also changed my diet and exercise patterns. My brain is no longer a swirl of indistinguishable thoughts, and I'm able to focus for more than a second at a time."

8 / 10
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  • Los...
  • May 3, 2009

For Depression "It has helped me a lot with my depression and anger problems. For the first time in 9 years, I don't wake up mad at the world with homicidal thoughts. The side effects that I experienced are dizziness when I stand up too fast and my loss of appetite (not a bad thing). I was overweight anyway. I've only been on it for 2 weeks and have lost 13 pounds, but it makes me feel so much better about myself."

10 / 10
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  • McL...
  • Taken for 1 to 6 months
  • May 20, 2014

For Depression "I tried a couple of different SSRIs and found that most of them gave me bad side effects and made me feel empty, so when I heard about Wellbutrin, I asked my doctor if I could try it. It's one of the few that also doesn't give you a decreased sex drive. I was a bit scared after hearing some of the negative reviews, but this medication works wonders for me. I have had no side effects at all, and within a day, I started feeling better. I would recommend this to anyone who hasn't had luck with SSRIs."

10 / 10
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  • mom...
  • Taken for less than 1 month
  • November 15, 2012

For Depression "This is the most amazing medication for depression! I have used it in the past, and I am so glad to start back on it again. I have had so many bad things happen, that it is time for some good. I am grateful for the way it helps me see the bright side of life, instead of living so unhappily and feeling hopeless. If you have ever thought of suicide, please don't do it. I know this medicine helped me from doing it in my past, it's wonderful. Problems are temporary."

10 / 10
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  • JIC...
  • Taken for 1 to 6 months
  • November 19, 2016

For Depression "I tried for 2 years after a major life change to get my life back. All the SNRIs and SSRIs gave me the worst side effects, and I became more depressed, dizzy, had migraines, and felt suicidal. This wasn't me, and every doctor wrote me off as being a bad patient. I was ready to throw in the towel and tried a low dose of Wellbutrin, and OMG. 2 months later, I was completely myself, and 6 months later, I'm medication-free. Don't give up, keep trying. I thought my life was over, and I was a difficult patient. Don't let message boards or doctors rule your life. If something isn't working, don't stay on it!"

9 / 10
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  • ber...
  • Taken for 1 to 6 months
  • January 11, 2020

For Depression "I started Wellbutrin 4 months ago at age 40. It was my first time using medication, although I've battled depression (and a subsequent eating disorder) since I was a child. A few years ago, anxiety started tormenting me. I couldn't live like this anymore. My GP started me on 150 mg, but after 6 weeks with no difference, upped it to 450. Finally, I realized the change: I was calmer, no longer judgmental towards myself, my unsatisfactory life situation, and my body. The anxiety and depression were gone. I treated myself with self-compassion and acceptance - all firsts for me! However, I also didn't care about exercising, and I've been an athlete and hiker all my life, so my energy level had evidently decreased. These past 4 months have been a lovely, gentle reprieve from the perfectionism and pressure I've put on myself my whole life. I've learned CBT and DBT therapies and am in recovery from my eating disorder. But now I want to feel energetic again and to wean myself off of Wellbutrin. I'm very grateful for it though!"

8 / 10
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  • Wei...
  • September 11, 2014

For Major Depressive Disorder "I feel great and it has been only 3 days. I have battled with Major Depressive Disorder and Post-Traumatic Stress Disorder, starting treatment in 2006. When I came back to the States, I was in 4 hospitals for months, treated by the best on 7-10 different medications at different times. I had ECT, etc. For me, all the medications did not do a thing for me but get suicidal thoughts and gained 60 pounds. One antidepressant medicine I was on for a few years was Lexapro. I was in Aruba and wanted to die. Through much thought and discussion, I weaned off of all the antidepressants. After 8 years, just last week a doctor said I never have been on Wellbutrin and put me on it. I have, for the last few months, been really down and out. Immediately, I feel better. It took only 8 years and wasted time in the hospital & ECT."

9 / 10
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  • Shy...
  • February 5, 2021

For Depression "I started taking 100 mg of Wellbutrin 2 months ago. I was prescribed it for ADHD, but I also suffer from severe depression. The first four days of this drug were absolutely awful, I cried and felt an extreme hopelessness. After the second week, the sadness was fading, but I felt numb. The only positive thing is that it has decreased my irritability heavily, like I used to snap at so many small things, and now I am unbothered, but this has been replaced with sensitivity and getting emotional/crying easily. It also has helped with my sex drive. It hasn’t helped my ADHD, and I also no longer have an appetite. Two days ago, I was bumped up to 300 mg a day, and the first day taking it, I went back into the same despair I felt, but the suicidal thoughts were worse this time, though luckily my boyfriend was there. I’m not sure if this is worth taking in the long run, but I’d rather be more emotional than have the irritability come back. Wishing everyone suffering from depression lots of love :)"

6 / 10
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  • sun...
  • Taken for 1 to 2 years
  • January 19, 2020

For Major Depressive Disorder "I have suffered from MDD for the majority of my life. I struggled for 5 years and through 16 different meds till we landed on Wellbutrin. One of the selling points for me is that this particular antidepressant is well known for not causing weight gain. And I can attest to that! On top of it not causing ANY side effects whatsoever, I started to feel better emotionally/physically within 2 weeks of being on Wellbutrin (Bupropion). I take two 150mg a day in the morning with my breakfast. I will say it did NOT help my anxiety even one single ounce, however with how much it has done for my depression, I will happily take a second medication for my anxiety. I have more energy, it gives me a huge boost in my mood, and that hasn’t changed! I haven’t had to switch or change meds and I have been on it for just over a year now. Thank goodness for this medication, seriously, a drastic difference, I finally get to be finally me!"

10 / 10
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  • gra...
  • Taken for 1 to 6 months
  • June 16, 2015

For Depression "I've been on Prozac for about 20 years, and it's been a lot of help, but at age 68, I found myself wanting to nap a lot more and my motivation decreasing. I switched to Wellbutrin, and once the therapeutic dose was established, I began to feel better within a week or two. I feel more energetic and yet more composed and at ease. I'm very pleased with this drug, not the least because my sex life has returned. I think my life would have been different if I'd started it 20 years ago."

10 / 10
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  • pea...
  • July 31, 2008

For Depression "I've been taking this medication for a couple of years. I no longer obsess over things and am no longer as depressed as I used to be. They seem to keep me in balance with my emotions. I would recommend this to anyone with depression and also compulsive behavior."

9 / 10
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180 Report
  • Bec...
  • January 13, 2015

For Major Depressive Disorder "Wellbutrin has saved my life. It's a miracle. About 6 months ago, I was diagnosed with major depressive disorder and localized anxiety disorder. I was put on Lexapro, which didn't help much, and the side effects were awful: total loss of sex drive, bad headaches, and nightmares every night. Then, about 3 months ago, they put me on 200mg of Wellbutrin daily, and I started feeling better within a week. It was incredible! I am now happier than I have ever been. I feel like a new, improved version of myself. My sex drive has drastically improved, but my appetite has not returned. In fact, I have lost weight despite not changing my eating or exercising habits. Other than those, I have no side effects."

10 / 10
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  • Anonymous
  • Taken for 6 months to 1 year
  • January 4, 2017

For Depression "Started Wellbutrin XL at 150 mg once a day to treat depression and anxiety, although was more concerned about depression. The first week I was on it, I was absolutely miserable. I did not sleep or eat at all, and was crying constantly, and I think it definitely worsened my depression. However, I called my doctor and had my dose lowered to 75 mg and not extended release, and I immediately felt better. I have been on that dosage for about 6 months now, and I feel amazing. I am able to control my emotions so much better, and I rarely have meltdowns (I used to have a complete meltdown anytime anything negative happened to me). I definitely plan on staying on Wellbutrin. Would just recommend you make sure you are on the right dose."

8 / 10
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  • Nig...
  • Taken for 2 to 5 years
  • June 28, 2024

For Depression "For years I was on SSRIs and they almost destroyed my life. This drug saved it. I feel like myself without that awful hazy effect that SSRIs produce. It helps a lot with anxiety and my PTSD. It also helped me quit smoking."

10 / 10
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  • Con...
  • January 5, 2014

For Depression "I've been taking bupropion 75mg twice a day for the past 6 weeks and I feel like I'm finally back to the real me. I'm 18 and have been dealing with depression, but this medication helped me tremendously. I was originally on Paxil, but due to sexual side effects, I switched to this and it restored my sex drive. I also have a little bit of anxiety, but this medication cleared that up as well. The first week was hard. I experienced heart palpitations, very anxious, ridiculous energy, and I was easily agitated. After the first week, those side effects slowly diminished and now I don't have them at all. That is the only reason I didn't give this medicine a 10. It saved my life. I HIGHLY recommend this to any who doesn't want sexual side effects."

9 / 10
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  • eli...
  • June 3, 2016

For Depression "Shortly after my 20th birthday, I developed what I later found out was major depression. After starting counseling, I reluctantly started taking Wellbutrin, and within a few days, I was a noticeably different person than I had been the past 6 months. I began to act like my old self again, gaining confidence, and for the most part, being free from all of my depression episodes that had occurred daily. The biggest side effects that I experienced were weight loss/loss of appetite and trouble falling asleep at night, but after about two weeks, those both went away. I've now been taking 300mg daily for about six weeks and feel great! I'd encourage you to give this medication a try because it can potentially really change your life."

9 / 10
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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.