Skip to main content

Wellbutrin User Reviews & Ratings (Page 3)

Wellbutrin has an average rating of 6.8 out of 10 from a total of 694 reviews on Drugs.com. 59% of reviewers reported a positive experience, while 23% reported a negative experience.

Reviews for Wellbutrin

  • Tired...
  • Taken for 1 to 6 months
  • December 6, 2015

For Depression "2 months ago, all I wanted to do was lay in bed all day & to be constantly distracted. I was always tired & Very irritable. I needed energy drinks to feel %u02BBawake%u02BB. I had constant thoughts of suicide and always over ate. Now after 6 weeks on the generic wellbutrin, I feel like a totally different person. I have energy to last me all day, I am much happier and I actually want to socialize with people. I laugh more & never cry. I am so happy this worked... I had a rough life and couldn't stop feeling like suicide was my only way out... This medicine is the best thing that ever happened to me."

Was this helpful?YesNo
207 Report
  • Happy...
  • June 16, 2014

For Depression "I started taking Wellbutrin 150mg one week ago. I suffer from mild depression, but I feel like I am going through a rough patch in my marriage/life and needed something to change. I exercise regularly, own a business and sleep well, but just didn't have that "get up and go" that I felt others had. So, my doctor had given me a prescription for Lexapro that had horrible side effects right off the bat. Heartburn, insomnia, and this kind of stressed out feeling that made me VERY uncomfortable. My doc gave me a new prescription for Wellbutrin and I take it the moment I wake up each morning. I feel Happy, Energetic and Ready to tackle the day. No insomnia, but I do have a reduced appetite. This may be just the ticket!"

8 / 10
Was this helpful?YesNo
234 Report
  • Anonymous
  • August 29, 2009

For Depression "I was set on trying Wellbutrin. I have tried Paxil and one other I can't even recall the name of. They made me feel like a zombie and my husband wasn't fond of them due to the sexual side effects. Wellbutrin was the hardest drug to get accustomed to. I went for a month having one side effect after the other. One week would be sleepless nights, the next would be general irritation at everything and everyone and perhaps the worst was nausea. I stuck it out and I am extremely glad I did. It has been amazing for me. I am much more motivated and excited about life. It increased my sex drive 100%! I also tend to be a social smoker and it obliterated that for me. I love this medicine. I take 400 mg daily."

10 / 10
Was this helpful?YesNo
314 Report

Frequently asked questions

  • garyg...
  • Taken for less than 1 month
  • August 6, 2023

For Depression "I'm on day 5 of Wellbutrin. I've had severe anxiety and depression for the past 10 years, and I'm 26 now. I've been hospitalized twice for suicidal feelings. Tried all different kinds of medications for the past 8 years. I had no hope anymore. I switched doctors this week after getting fed up with my old psychiatrist who I felt didn't understand me and couldn't give me the care I needed. My new doctor understands me and she started me on Wellbutrin this week. The first day of taking Wellbutrin I felt relief. The fog of hopelessness was lifted, and although my situation is still bad, I now feel like I have the ability to overcome it. Now on day 5 I'm feeling much better, like I can actually focus more on the present moment rather than being stuck in my head. Side effects have included dry mouth, some stomach issues, anxiety, and insomnia. My doctor gave me trazodone to sleep better which has helped. Please do not lose hope or be scared to try medications. They can help."

Was this helpful?YesNo
34 Report
  • Maths...
  • Taken for 1 to 6 months
  • October 14, 2013

For Depression "I started taking 150mg Wellbutrin SR about a month ago to treat severe atypical depression, and it has been nothing short of miraculous for me. The first two weeks were rough. I had some heart palpitations brought on by a combination of the meds and caffeine, so I had to stop the caffeine. I also had to work through a bit of insomnia early on, but that side effect has subsided, and now I actually sleep and wake well rested. For the first time in a decade, I'm hopeful. My negative thoughts are still there, but unlike before, I have control over them. I can manage them in a non-destructive way. Words cannot express what it feels like to know that you can, for the first time in so long you can't remember, function as a normal person."

10 / 10
Was this helpful?YesNo
236 Report

Are you taking this medicine?

  • Chief...
  • December 5, 2014

For Depression "Recently I retired from public safety. I should have been happy and content to have a lot of free time. My friends all said I looked rested and better than I had in years. What they did not know is how depressed I was and how much I missed the work and my work friends. Reluctantly my doctor prescribed Bupropion HCL 150 mg for seven days then 300 mg daily in the AM. After the first day, I was already feeling better. I just finished the first two weeks and I'm feeling so much better. Occasionally I still have negative thoughts. Side effects include anxiety and an elevated BP. I'm happy with the results and believe the medication has taken me away from the edge. I will post updates periodically."

7 / 10
Was this helpful?YesNo
215 Report
  • Tabitha...
  • Taken for 1 to 6 months
  • January 14, 2017

For Depression "I am a 57 year old breast cancer survivor who has been in excellent shape, trim and happily married. After menopause, I developed insomnia, weight gain and depression. Can no longer take estrogen due to breast cancer, which made me feel tired all the time. Thyroid medicine helped but not enough--No energy and lost interest in doing things. My doctor insisted I try SSRIs such as Lexapro and Zoloft, but had bad side effects. I tried many supplements--not much help. I tried Bupropion HCL SR 150 mg. It worked right away. I take early morning and have energy all day. I did not have side effects (lost 2 pounds! and insomnia if taken after 10 am). Changed my life! Been on it 4 months."

10 / 10
Was this helpful?YesNo
176 Report

More FAQ

  • Marley
  • Taken for less than 1 month
  • October 17, 2019

For Depression "I have been on anti-depressants for decades. My P.A. put me on Zoloft and I took it for months with no effect. I asked to try Wellbutrin, as it helped me back in my 30s. Been on it three weeks. I CANNOT explain how bad the anxiety is. I cannot sleep. I cannot speak well nor, can I remember words or their spellings. Let us not mention that sudden feeling of rage and anger. Decided to do some research and find other people's experiences and here they are. Many with the same issues. Perhaps all of this would dissipate over time, but I can't live like this. I will discontinue using and I hope that this helps someone. Please keep fighting, NEVER give up. I'm going to keep searching for the right cure for me."

1 / 10
Was this helpful?YesNo
122 Report
  • Didi
  • Taken for 1 to 6 months
  • January 17, 2019

For Depression "I have been on other meds for depression, but Wellbutrin has been the best medicine the doctor could have put me on. This med has changed my life from night to day. I did not have the side effects with this one like I did with the others. I can not praise this med enough. Before being put on Wellbutrin I cried all the time, could not get my appartment dark enough and I just wanted to be alone all the time. I can't thank my doctor enough for putting me on Wellbutrin. I have also lost some weight and my sugar cravings are gone. Love Wellbutrin."

10 / 10
Was this helpful?YesNo
136 Report
  • Alexa...
  • Taken for less than 1 month
  • December 30, 2023

"I have GAD and ADHD, as well as going through postpartum depression which is presenting mainly as rage. I haven't taken any sort of medication for 10 years to treat the anxiety, and I've only now just accepted the fact that I needed to try some medication for my ADHD. I'm nervous about stimulants so my doctor prescribed 150mg Wellbutrin XL. I must say - I am pleasantly surprised. No medication (I have tried about 5 different antidepressants in my life) has made this much of a difference for me. I've only been taking it for 3 days and I'm already noticing a huge shift in my mood, and I randomly got up and scrubbed down all the surfaces in my kitchen (which haven't been done for god knows how long). I feel the urge to be productive and I'm less irritable with my kids. I'm hoping this continues and so far I have no negative side effects whatsoever, which shocks me. Give it a try!"

10 / 10
Was this helpful?YesNo
18 Report
  • Jasey...
  • Taken for 1 to 2 years
  • November 21, 2014

For Depression "When first taking Wellbutrin, my mouth became really dry, I got a few weird headaches, and I felt some physical numbness when I touched my skin; However, after a month the symptoms were almost non-existent and my depression and anxiety improved drastically. Also, my doctor prescribed it to me to help with ADD/ADHD. I noticed that my focus was also better. This may be simply because anxiety can cause you to lack attention and it fixed the anxiety, but either way it worked great for me."

10 / 10
Was this helpful?YesNo
209 Report
  • darkd...
  • January 7, 2015

For Depression "I've been struggling with depression and anxiety/panic attacks since I was a kid. I'm now 36. I tried every antidepressant they threw at me from Celexa to Zoloft. None of them worked and came with side effects I couldn't handle. Weight gain and loss of sexual function. When my psychiatrist suggested Wellbutrin I was afraid of more side effects, but I was desperate. I also take Valium and Klonopin for my anxiety so I'm not sure if those might mask any increased anxiety, but I have to say, I noticed a difference the first day. I take 200mg SR in the morning and I've got more energy and almost no interest in smoking, which is a bonus. It's only been a week but I feel an improvement every day. I think I finally found the right one."

10 / 10
Was this helpful?YesNo
204 Report
  • Niki9...
  • Taken for 1 to 2 years
  • October 27, 2014

For Major Depressive Disorder "I have Major Depressive Disoder, Post Traumatic Stress Disorder. I've taken Zoloft, Paxil, Citalopram. I'm currently taking Wellbutrin 300XL, Cipralex 25mg. Cipralex only got me out of suicidal thoughts, but Wellbutrin healed my brain. When my psychiatrist first prescribed it to me, I couldn't afford it so I didn't fill my prescription. When she found out, she gave me some samples. Within a week I got motivation. I had forgotten how it felt to want to do things. My thoughts were more cheerful. I was able to laugh and joke. My PTSD paranoia went down. I began walking, quit smoking, went back to work, traveled, and met the love of my life. It made Me me again! I'm still taking it and will for as long as my brain needs it."

10 / 10
Was this helpful?YesNo
202 Report
  • Kat
  • Taken for 1 to 6 months
  • July 26, 2023

For Depression "At week 3 of taking Wellbutrin, I got a serious serotonin rush that lasted only 1 day (it was fabulous) and by week 4, I had superpower concentration. My work was getting done faster, and I was clearheaded. But by month 2, it all went away. I am starting month 4 and I am unable to concentrate again, I am crying, I feel 'down'. I feel exactly the same as before I started. I don't want to go on a higher dose because, where does it end? For me, I'd have to say it didn't work."

1 / 10
Was this helpful?YesNo
31 Report
  • Faith...
  • Taken for less than 1 month
  • November 27, 2021

For Depression "I am on week 3 on Bupropion 150 SR , I went off Paroxetine cold turkey and started this. First week I was tired all the time and had some weird nightmares that went off starting 2nd week. Then the 2nd week I felt awkward I was not me , I was very irritable, didn't want to be around people, had some headaches that week and wasn't interested in doing many things, I was about to quit but my doctor told me to please give it a try until week three when it is supposed to start working (from week 3 to 6 ) so I did with a lot of effort and I am so HAPPY I DID HANG IN THERE !! I FEEL SO MUCH BETTER today is my day 22 and I at last feel peace, joy and motivation again to do things I didn't wanted to do before. I am eating less not so hungry, stopped smoking and do not need caffeine to function as I did before. It doesn't have side effects on libido like paroxetine, so far It has been worth to wait 3 weeks of not feeling so well IT IS WORTH IT PLEASE HANG THERE !!! Pray for all to feel happy.."

8 / 10
Was this helpful?YesNo
72 Report
  • Anonymous
  • Taken for 1 to 6 months
  • January 8, 2015

For Depression "Wellbutrin SR 150s, which initially had positive outcomes on my depression, probably the best I've tried, and I've tried a lot the past years. It took a bit to get the optimal dose. At 300 mg it was causing a cascade of side effects, anxiety, palpitations, sweating. Doc helped me back down to 100 mg with no side effects. The depression is just as gone as the initial 300 mg. Wellbutrin also developed a positive outcome in mere days - a major plus."

8 / 10
Was this helpful?YesNo
193 Report
  • young...
  • April 17, 2019

For Depression "After a few bouts of mild depression, I entered a more major depressive period about two years ago. I told my psychiatrist I was so sad "my teeth hurt". I was unmotivated, hopeless, and really just sooo sad all the time. My doctor tried to give me an SSRI but I pushed for Wellbutrin due to the lack of sexual side effects and weight gain with SSRIs. The first couple of weeks on it, I was on a total high. I remember dancing around with my kids and literally jumping around at the playground like a crazy lady. Once that levelled off I was just "me" again. No other way to put it than I feel totally normal now. I still get sad, happy, angry (so I'm not flat) but all within a normal range. The ONLY negative for me is that if I miss a dose I turn into a raging crazy lady. I feel like I'm withdrawing from hard drugs. It definitely makes me scared of when the time comes to try and get off of it, but for now it's worth it."

9 / 10
Was this helpful?YesNo
120 Report
  • Birds...
  • Taken for 5 to 10 years
  • April 6, 2020

For Major Depressive Disorder "I’ve been on Wellbutrin xl with my dosage varying from 300-450. This is the best antidepressant I have every tried and I have tried many. Whenever I increase my dosage I do experience side effects for a little while. Mostly I’m more easily annoyed and fidgity. They always go away over time. This is the only medication that has been able to increase my energy levels and sex drive. I also have GAD, have had psychotic depression in the past, and panic attacks in the past. This drug doesn’t exacerbate any of those problems for me. I’m also on Seroquel though so that probably helps with my sleep. Many antidepressants have given me terrible headaches but this one does not. I get migraines a few time’s a year, same as before. If you’ve found that other antidepressants don’t work for you I highly recommend this one. Almost no side effects and definitely gives me the energy I need."

10 / 10
Was this helpful?YesNo
98 Report
  • Janedoe
  • March 7, 2020

For Depression "DO NOT TAKE THIS IF YOUR PRIMARY ISSUE IS ANXIETY. I got on this medication because I was having trouble with anxiety and insomnia. My NP wanted to start me on Wellbutrin 150mg XL and I kept reiterating to her that I have no depression what so ever, I’m just anxious, but she said it would help. Within 2 weeks I was so nauseated, in a complete brain fog, my anxiety got so much worse, my heart would race, I was having panic attacks daily, couldn’t sleep, my mind was racing non stop, and although I’ve never felt as if I had issues with depression I was so depressed on this medication! I went from being very high functioning with mild to moderate anxiety to completely useless on this medication. I called into work multiple times (which I had never done before-I’m a nurse) I couldn’t focus was so disoriented and felt like I was just floating. I stopped and feel much better after a few days and I got on a prn benzo for anxiety."

1 / 10
Was this helpful?YesNo
98 Report
  • nebMN
  • Taken for 6 months to 1 year
  • February 7, 2014

For Depression "I was diagnosed with major depressive disorder a few years ago. I've tried basically all SSRI anti-depressants. They did nothing for me other then make sex impossible and gave me leg tremors as well as massive weight gain. I switched to Wellbutrin and my sex drive is back to normal my weight is dropping and I feel a lot better. I recommend this medicine to anyone struggling with SSRI's and their many side effects."

9 / 10
Was this helpful?YesNo
190 Report
  • Kathe...
  • Taken for less than 1 month
  • July 20, 2014

For Depression "I am on Day 3 and I am starting to notice some if not all of the effects. My mood is stabilising and I am finding my motivation returning to me. I need it for when I get into my doctoral program! I can find pleasure in things I enjoy again. I don't have overtly pessimistic and sad thoughts as much. I'm not crying as much. Before I started taking this medicine I was not at rock bottom, but I did not want to feel like awful anymore. Depression is a real disease. The medications do help."

10 / 10
Was this helpful?YesNo
183 Report
  • Miami...
  • August 7, 2013

For Depression "I am a 25 year old woman and started taking this 6 days ago along with clonazepam for anxiety. 300 mg of Bupropion once a day (mornings) and clonazepam twice a day (once in the morning and once in the evening). I have to say that...so far THIS ROCKS. I was suffering from depression, obsessive thoughts, anxiety and panic attacks for months. I stopped taking Zoloft after a year because I gained 60 lbs on it. Now with Wellbutrin, I have no side effects except loss of appetite and more energy. I feel more energetic, happy (almost "giddy") and hopeful for the future. My anxiety and depression was debilitating and this saved my life. I can't wait till the full effects kick in. 6 days in and I feel the difference."

9 / 10
Was this helpful?YesNo
194 Report
  • RhettV
  • July 6, 2017

For Major Depressive Disorder "I've been on Wellbutrin for about three months now. It was prescribed to me by a psychiatrist due to depression and anxiety, low cognitive function and bad working memory. Wellbutrin started working on me around week 8. Mood lifted immensely, better executive function, lower anxiety, became much more goal oriented. Stopped delaying and procastinating everything, became interested in my hobbies again, felt clear headed, more energetic and general mental well being. Struggle with working memory a bit, still."

10 / 10
Was this helpful?YesNo
137 Report
  • Monica
  • Taken for 1 to 6 months
  • September 23, 2019

For Major Depressive Disorder "Wellbutrin has been amazing. I have anxiety, depression, ADHD & PTSD. It was hard getting used to this one as it amped me up a lot. Take with food as early as possible. The constipation and anxiety did subside. Now I can’t believe I’ve allowed myself to be so sad when this stuff even makes air blowing on my face feel incredible. Here’s what I found - after trying everything SSRI wise, if you have bad side effects right away, it’s not the right drug. Taking this Wellbutrin, I knew right away, was totally different. I did need Xanax to be a crutch with this at first because of the anxiety...but I was also tapering off gabapentin at the time so who knows why I was that anxious. So this is how “normal” people feel w/o depression...interesting. Lucky."

10 / 10
Was this helpful?YesNo
102 Report
  • jaf
  • April 1, 2013

For Depression "I'm a 19 year old college female. I was struggling with anxiety and depression for about six months and went on Zoloft in December 2012. It made me even more depressed, even though it helped with the anxiety. Zoloft also made me a zombie (napping for hours during the day, no motivation to socialize, no motivation to do schoolwork, nothing). I went off it about a month ago and switched to 150mg of Wellbutrin daily. I noticed a difference the FIRST day. It gave me the energy/positivity I have been lacking for months and I finally am starting to feel like myself again. I recommend it to anyone who Zoloft didn't work for or who needs that extra boost to come out of a fog."

10 / 10
Was this helpful?YesNo
196 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.