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Wellbutrin User Reviews & Ratings (Page 4)

Wellbutrin has an average rating of 6.8 out of 10 from a total of 756 reviews on Drugs.com. 58% of reviewers reported a positive experience, while 23% reported a negative experience.

Reviews for Wellbutrin

Commonly mentioned side effects
  • Mon...
  • Taken for 1 to 6 months
  • September 23, 2019

For Major Depressive Disorder "Wellbutrin has been amazing. I have anxiety, depression, ADHD & PTSD. It was hard getting used to this one as it amped me up a lot. Take with food as early as possible. The constipation and anxiety did subside. Now I can’t believe I’ve allowed myself to be so sad when this stuff even makes air blowing on my face feel incredible. Here’s what I found - after trying everything SSRI wise, if you have bad side effects right away, it’s not the right drug. Taking this Wellbutrin, I knew right away, was totally different. I did need Xanax to be a crutch with this at first because of the anxiety...but I was also tapering off gabapentin at the time so who knows why I was that anxious. So this is how “normal” people feel w/o depression...interesting. Lucky."

10 / 10
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  • Car...
  • Taken for 1 to 6 months
  • April 19, 2017

For Depression "I have been taking 150 mg of the generic of Wellbutrin for the past month. I can't believe how amazing I feel! After dealing with depression for the past 4-5 years, I finally feel like myself again. I was diagnosed with PMDD and mild depression but tried to deal with both of these with Prozac and hormone birth control. After three months of Prozac, I quit. It made me tired and took away my libido. It didn't help my depression at all. I've tried three different birth controls (I'm 46... it wasn't for birth control, just to try to help my hormone levels.) Nothing helped my depression. Finally, my doctor prescribed Wellbutrin. I filled it but didn't take it for 8 months because I was afraid of the side effects. Now I could just kick myself!"

9 / 10
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  • c3l...
  • May 16, 2013

For Depression "This medicine really works for me and has really improved my quality of life and perspective on things. I'm 18, and I have been on this for a little over 6 months, and I would say the only bad side effect is dry mouth, but if you just drink a lot of water, you'll be fine. I like it because it has helped me stop 'binge' eating. I don't have cravings for food or cigarettes anymore, and I completely stopped smoking. I'm never tired anymore, Wellbutrin definitely gives you energy in a good way. Sex drive is completely normal, and I still have normal emotions, unlike when I was on Celexa or Prozac where I felt so emotionless. I lost 20 lbs, but I am healthy and fit and a lot happier with myself."

9 / 10
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Frequently asked questions

  • sen...
  • Taken for 1 to 6 months
  • April 9, 2024

For Major Depressive Disorder "I was on a low and had no energy and was self-medicating with alcohol. I was always in bed, no energy, just blah! Crying all the time, missing work. I decided to seek help, and my doctor put me on this med a month ago. All I can say is wow!! I've not been stressed and worrying about every little thing. I have no urge to drink at all, and I'm able to get out and do stuff with my kids. Depression sucks, but I'm glad this med is working for me."

10 / 10
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  • Anonymous
  • March 18, 2010

For Depression "I have been taking Wellbutrin continuously for 20 years. If it were not for this miracle drug, I would be dead. There is no doubt in my mind that my intractable depression was arrested with Wellbutrin. I have a chemical imbalance that is permanent. I once went off Wellbutrin for a month because I was taking another medicine. Within three weeks, I was having suicidal ideas. Needless to say, I will not go off it again. My doctor assures me it is safe for lifelong use."

10 / 10
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  • Mea...
  • Taken for less than 1 month
  • September 24, 2018

For Depression "Have been on Wellbutrin SR 150 twice daily. BEST CHOICE I MADE!! I am a person that thrives off of happiness, feeling great, making others happy, etc! After one week, I am me again!!! HAPPY, SECURE, JUST ME!! I noticed it has helped chill me out. For those who don’t find this medication to work, maybe it is the wrong drug for your chemical imbalance. It is just a matter of finding the right drug for the right person. I'm thankful"

9 / 10
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  • Sti...
  • Taken for 6 months to 1 year
  • May 14, 2017

For Major Depressive Disorder "I take this drug to help combat Major Depression (had for 1.5 years). I have also tried Paxil (made me crazier), Prozac (did nothing for me) and Effexor (worked well but the sexual side effects were worse than the depression). I started Wellbutrin at 150mg and slowly increased to 300mg after completely titrating off Effexor, had to increase to 450 because MD came back. So, here is the deal - at first this drug feels awful (realize that most antis are like this in the beginning). I had to stick with it for at least a month and the extreme anxiety has always normalized. But OMG - this is the first drug that motivates me to get out of bed and face each day. For me it helps to balance my down mood & 'urge to isolate' and sabotage my day."

10 / 10
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More FAQ

  • Ron...
  • Taken for less than 1 month
  • March 12, 2025

For Depression "This medication was very hard to use, there was stomach pain and acid reflux. Sleep was poor, and I couldn't sleep more than 2 hours without waking at night. I became very agitated with anxiety and sadness that would come and go very fast. The agitation became worse, and I was looking for anything that irritated me to lash out and went into a rage and confronted others. My heart was always around 100 beats when I was at rest. I also had very strange thoughts that worried me I was losing control of my thoughts."

1 / 10
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  • Top...
  • June 29, 2018

For Major Depressive Disorder "I've been on multiple SSRIs and was convinced that antidepressants just didn't work. My doctor insisted that I try something else because my anxiety was dictating every aspect of my life. I'm so glad that she did. After about 2 weeks on Wellbutrin, I began to realize that I felt really happy for the first time in over 2 decades. The only side effect I've really had is occasional mild irritability. It lasts for about a half hour and happens once every week or two. Though as I've been on the medication longer, the side effects are less severe. I know this medication isn't for everyone, but whatever was wrong with me, Wellbutrin fixed it. If you're struggling with anxiety or depression, be honest with your doctor. If your medication isn't helping you, tell your doctor. If your doctor won't help you, find a new doctor. You can do this, and you deserve to be happy."

10 / 10
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  • Aug...
  • Taken for 1 to 6 months
  • January 13, 2020

For Depression "Having fallen into a serious depression which led me to have great difficulty in doing everyday things, getting up in the morning, brushing my teeth, washing, and also couldn't get important sleep. It was getting really difficult. My neurologist prescribed Wellbutrin XR 150mg once a day in the morning. I was very hesitant to take the drug for fear of the side effects. Today, after 3 months of treatment, I sincerely thank her. I have found energy, reconnected with my social relationships, etc. In terms of side effects for me, it's mild: dry mouth, a few palpitations often at night, and slight weight loss. In 3 months of treatment, I lost 4 pounds."

8 / 10
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  • sam...
  • Taken for less than 1 month
  • June 8, 2023

For Depression "I took two doses of 150 XL bupropion, on the second dose, I have immediate ear ringing, fullness, and pressure in my ears. I’ve never once had an issue with my ears in my life. I’m very young and healthy. Months later and after multiple ENTs, I have permanent tinnitus from this drug. It shouldn’t be legal."

1 / 10
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  • Ale...
  • Taken for less than 1 month
  • December 30, 2023

"I have GAD and ADHD, as well as going through postpartum depression which is presenting mainly as rage. I haven't taken any sort of medication for 10 years to treat the anxiety, and I've only now just accepted the fact that I needed to try some medication for my ADHD. I'm nervous about stimulants so my doctor prescribed 150mg Wellbutrin XL. I must say - I am pleasantly surprised. No medication (I have tried about 5 different antidepressants in my life) has made this much of a difference for me. I've only been taking it for 3 days and I'm already noticing a huge shift in my mood, and I randomly got up and scrubbed down all the surfaces in my kitchen (which haven't been done for god knows how long). I feel the urge to be productive and I'm less irritable with my kids. I'm hoping this continues and so far I have no negative side effects whatsoever, which shocks me. Give it a try!"

10 / 10
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  • Jan...
  • March 7, 2020

For Depression "DO NOT TAKE THIS IF YOUR PRIMARY ISSUE IS ANXIETY. I got on this medication because I was having trouble with anxiety and insomnia. My NP wanted to start me on Wellbutrin 150mg XL and I kept reiterating to her that I have no depression whatsoever, I’m just anxious, but she said it would help. Within 2 weeks, I was so nauseated, in a complete brain fog, my anxiety got so much worse, my heart would race, I was having panic attacks daily, couldn’t sleep, my mind was racing non-stop, and although I’ve never felt as if I had issues with depression, I was so depressed on this medication! I went from being very high-functioning with mild to moderate anxiety to completely useless on this medication. I called into work multiple times (which I had never done before - I’m a nurse). I couldn’t focus, was so disoriented, and felt like I was just floating. I stopped and feel much better after a few days and I got on a PRN benzo for anxiety."

1 / 10
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  • Min...
  • Taken for 1 to 6 months
  • April 23, 2024

For Major Depressive Disorder "When my doctor offered me Wellbutrin, I said sure like I always did. I've been on a variety of different medications over the past 10 years, and none of them seemed to give me hope with my MDD. I was put on Bupropion about a month ago. I've always said there's no magic pill to make you get out of bed in the morning or cure depressive symptoms. I WAS SO WRONG! On Bupropion, I feel like a child again! I have found interest in activities that all seemed too much of a hassle to do, or that I didn't do because I had no faith in my capabilities. Bupropion has given me a newfound confidence in myself; I feel like someone has given me my soul back, and I'm able to feel things I never thought I'd be able to experience again. There are some side effects to Bupropion, but they're worth it to me as the medication is making it able for me to function. For me, it's weight gain, tinnitus, and joint pain."

8 / 10
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  • tha...
  • Taken for 1 to 2 years
  • October 21, 2018

For Depression "I have been taking Celexa for a while to treat depression, and while helpful, it had made me very numb, and I was still feeling occasional episodes of mild depression. My provider added Wellbutrin, and what a difference! Wellbutrin gave me a boost of mental energy and feelings of well-being that I had never felt before. I am currently doing very well with the combination of Celexa and Wellbutrin. I feel better than I ever have in my life. I've been on this fantastic combination for a year. Highly recommend."

10 / 10
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  • Ano...
  • July 18, 2013

For Depression "I just took the first 100mg pill a few hours ago and I feel different. I feel almost normal. I'm not thinking about being depressed, and my energy is almost back to normal. No antidepressant, antipsychotic, or mood stabilizer has ever done that! If this feeling keeps up or gets better, I don't know what I'll do. I'll probably cry tears of joy. Is this what normal people feel like?"

10 / 10
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  • Ska...
  • July 19, 2015

For Depression "Y'all! I am one of these people who cannot say enough about bupropion! It has changed my life after only day 8. Such a subtle but powerful shift in perception and decrease in troublesome habits (smoking one of them, but also irrational anxiety getting on train, rushing down the street for no reason, rushing through dinner) has decreased by drinking, made me feel less weighed down. There are side effects the first few days, but they will go away! Stick with it, and you won't regret it."

10 / 10
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  • Lan...
  • Taken for 1 to 6 months
  • May 25, 2019

For Depression "The heightened sex drive Wellbutrin (bupropion) is so powerful that I'm even having awesome sexual dreams in my sleep. It hasn't helped me to stop smoking, but I smoke very little to begin with, so maybe that's why I don't notice a difference. It totally smoothed out my mean mood swings. I just love it. I have zero bad side effects. I do believe the medication helps females' libido more than it helps most males, but I could be wrong."

10 / 10
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103 Report
  • Sam...
  • Taken for less than 1 month
  • October 31, 2015

For Depression "I'm in my early 40s and have noticed the last couple of years I've become very agitated over nothing! Always yelling at my teenager and I could literally feel my blood pressure raising over the smallest things. Also this last year for some reason I became depressed. I didn't ever want to get out of bed or leave the house to do anything. I've always had a bad opinion about antidepressants, but I knew SOMETHING had to change. I reached out to my doctor who gave me 100 mg of generic Wellbutrin, and the very first day I noticed I was calmer! I fell asleep 2 hours later but woke up refreshed. I just finished day 3, and I swear I feel fantastic! Not only have I not yelled even once, I don't feel angry at all! And I want to do stuff again. Very happy"

9 / 10
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  • jud...
  • Taken for 1 to 6 months
  • June 11, 2022

For Depression "I've had moderate depression and some anxiety most of my life. It manifests mostly in the forms of low energy, worrying, irritability, and avoidance. Dishes piling up, laundry not getting done, car interior a mess, etc. I tried two SSRIs (Lexapro & Zoloft) before switching to Wellbutrin, which is a dopamine reuptake inhibitor. Dopamine! That was the answer. It wasn't a serotonin problem, it was a dopamine one! The SSRIs worked okay, but I was always tired and foggy. I gave each 6 months. I eased off the SSRIs and eased into the Wellbutrin. I only take 150 mg at the moment. I'm almost 4 months in, and I can't believe the improvement. I bound out of bed in the morning and start getting stuff done. My attitude is positive, excited, eager for the day and being alive. I can't believe it. All those years with the background hum of depression, even if mild at times, made me think feeling that way was normal. It wasn't! This turned out to be the perfect fit for me."

10 / 10
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  • Nam...
  • May 20, 2016

For Major Depressive Disorder "I was at age 50 severely depressed about my future because I had screwed my life up so bad. I was so full of fear and anxiety as well. I started addressing things in my life one at a time, and one of those things was finding a good psychologist. I chose to get on Wellbutrin, 300 day and like others felt it working by day two. Within three months it settled in and completely changed my life. I'm happy to wake up, I enjoy work, I take care of myself, people respond to me better. I'm not worried about the future. I like myself again. It's been a miracle drug for me - all positive, no negative."

10 / 10
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  • pwn...
  • Taken for 1 to 6 months
  • January 25, 2016

For Depression "I was prescribed Wellbutrin by my doctor when I told her that I was having a very difficult time getting out of bed and wanting to be productive one month ago. My doc prescribed me Wellbutrin 150 xl, which has as an added bonus made me completely stop smoking and even become repulsed by cigarettes. No negative side effects. Wellbutrin has reduced my urge to drink alcohol by 90%, and when I do drink, I feel intoxicated after only 2 or 3 drinks. I have been exercising five days a week and eating well to assist in mood elevation. I have more motivation and energy now than a month ago. I am impressed with this medication."

10 / 10
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  • Can...
  • August 20, 2015

For Depression "All I can say is Wellbutrin has substantially increased my quality of life. I was so scared about side effects that I waited years to try antidepressants. I was on Celexa, and when that failed, I was put on Zoloft, which also did me no good. Wellbutrin not only brought me out of a deep depression, it's caused me to be active, and my weight is now in the normal range. I'm also more organized and positive than I've ever been. My family members, who were initially against me taking Wellbutrin, have changed their opinion because they see me enjoy life again."

10 / 10
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  • Anonymous
  • June 18, 2009

For Depression "I have recently decided to start Wellbutrin after 2 years on Zoloft. Although I felt the Zoloft worked well, there were some unfortunate side effects. I asked my doctor if I could give Wellbutrin a try (I had also recently picked up smoking again so I mentioned that). Well, here's the good news... my mood has remained stable (I simultaneously tapered off the Zoloft). I have been better able to focus at work, cigarettes tasted disgusting, and I have noticed a decrease in my desire to engage in compulsive activities. The cons... food doesn't really taste all that great, I'm extremely thirsty, and I was initially a little on edge at first (this has since gone away). The other surprising effect was a marked improvement in sexual response."

9 / 10
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  • win...
  • Taken for 1 to 6 months
  • June 5, 2014

For Depression "Wellbutrin is amazing. Prior to Wellbutrin, I was put on Zoloft, Prozac, and Valdoxan, all of which either killed my sex drive, did nothing, or made me too sleepy to function. For 2 years, I stupidly went off medication and just thought everything in life was crap, and probably said some things I regret to people. Eventually, it came to the point where I was failing at work and angry at everyone. The ADHD medication I was taking also worsened my depression. With Wellbutrin, I have been on it for around two months, and I feel great. I have energy, more motivation, increased libido, and I feel content, although I still have moments. Also, I have lost more than 5 pounds without dieting or exercising."

10 / 10
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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.