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User Reviews for Zoloft

The following information is NOT intended to endorse drugs or recommend therapy. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners in patient care. Learn more about Zoloft.

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Condition Avg. Ratings Reviews Compare
Premenstrual Dysphoric Disorder
8.4
   
33 reviews 44 medications
Obsessive Compulsive Disorder
8.1
   
83 reviews 11 medications
Postpartum Depression
7.7
   
17 reviews 7 medications
Panic Disorder
7.6
   
226 reviews 19 medications
Post Traumatic Stress Disorder
7.6
   
52 reviews 5 medications
Social Anxiety Disorder
7.5
   
177 reviews 6 medications
Depression
7.1
   
419 reviews 80 medications
Major Depressive Disorder
7.1
   
66 reviews 46 medications
Summary of Zoloft reviews 7.7 1,073 reviews

Reviews for Zoloft

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For Major Depressive Disorder "Setraline has done absolutely nothing to help my depression, it brought on anhedonia which made me feel really down and just deeply sad. Waited 3 weeks and made me feel way worse, this is the 2nd SSRI I have used. I luckily respond very well to bupropion XL 300mg and it saved me from the complete hell I was in due to the SSRI. I don’t truly believe serotonin is the key to happiness, especially because I responded a hell of a lot better to Wellbutrin which is a norepinephrine and dopamine reuptake inhibitor. All I can do is hope the new medication of ketamine nasal spray will do something good for most people who are suffering."

   
1.0

james1738 (taken for less than 1 month) January 17, 2018

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For Depression "This medication has not helped me in any form. I lost a lot of my appetite, and slept all the time, and was still tired. My depression worsened on Zoloft. I do not recommend Zoloft for depression."

   
1.0

Just a person. January 16, 2018

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For Depression "I was prescribed 50mg by my GP. 1st day felt like I was on speed lots of energy, jittery. 2nd day I felt neutral, anxious. 3rd and last day of taking, I woke up in the middle of the night with suicidal thoughts which was very overwhelming and scary. Also lost appetite and 2kg in just 3 days. Terrible stuff."

   
2.0

Guy57664 (taken for less than 1 month) January 13, 2018

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For Depression "Took 150 mg for 2 years...helped a lot but always tired and lack of motivation...dropped to 100 mg and motivation is better...but tad more anxiety but I guess it’s better to be on the lowest possible dose for less side effects and dependency"

Quincypondex1 (taken for 2 to 5 years) January 7, 2018

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For Depression "Works great although I have spontaneous erections. This is very embarrassing for me"

   
8.0

Jonboy123 January 5, 2018

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For Social Anxiety Disorder "I was experiencing horrible anxiety attacks I felt like I was having a heart attack, I was scared to fall asleep and not wake up. I was scared to drive, I felt like I was going crazy. My doctor started me on Zoloft 25mg which made it worst at first BUT than she increased it to 50mg and after a few weeks and I started feeling about 50% better so on my next visit I was increased to 100mg and I was terrified to increase it. Now I'm doing about 90% better, sometimes I feel like I'm about to get an anxiety attack but after a few seconds it goes away. I have a follow up appointment in 6 weeks we'll see what my Doctor says. If you're going through this and your Doctor prescribes you medication take it & say a prayer"

   
9.0

LAUREZZY (taken for 1 to 6 months) January 4, 2018

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For Panic Disorder "After finally going to the doctor to get on medicine for my panic attacks he put me on Zoloft. I started it that same Friday. Starting the next day I had a constant panic attack till the next Sunday basically. With the help of my husband and mother they decided to take me to the ER. I was low on fluids and they had to give me other medications to calm me down. After that my doctor switched me to Xanax XR and it has done wonders for me! I would never take Zoloft again, please be careful"

   
1.0

Bdan January 3, 2018

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For Panic Disorder "I have been on zoloft for 11 months and it has literally been the best thing I've ever done for my mental health. Before taking Zoloft I tried everything natural including exercise, meditation, therapy, balanced sleep, eating well and so on. I am not underestimating those things for balance but despite my commitment to a healthy life I was still having constant panic attacks which would then spiral me into depression. I can't believe the level of life quality I have from Zoloft. I feel so much more relaxed, able to access my logical side when challenge arises. At first few side affects like churning stomach, sweatiness, inability to orgasm and weirdly dilated pupils. They all subsided in a month of talking drug! Please give it a go."

   
10

Green Stone (taken for 6 months to 1 year) January 2, 2018

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For Panic Disorder "I’m on 7 day of sertraline and I feel a complete mess. I’m panicking, afraid, and crying. On my 3rd day I felt good but yesterday it’s got worst. I’m on 25mg and we don’t have a therapist were I live so I don’t know what to do"

   
5.0

Cherrypick December 22, 2017

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For Depression "I started this medicine for depression and anxiety. Every medicine works different on everyone but this medicine altered my life completely and not in a good way. I turned into a person who wasn’t me, I lost friends from my changed personality, ruined relationships, went from 130lb to 160 pounds in just three months. I cried and was more suicidal and sad then I’ve ever been. People would always tell me “what happened to the old you”. I didn’t know and went to my doctor and was quickly switched off and went onto a different medication and getting off of it was the best thing. My personality went back to the old me and I regained my relationship and friendships back and I lost almost all the weight I gained. Zoloft wasn’t for me personally"

Anonymous December 21, 2017

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For Depression "This drug changed my life. I was really struggling my sophomore year of high school to the point where I couldn't leave my house. I'd struggled with anxiety my whole life but it got so bad I was paralyzed by it, leading me into an episode of depression. I started therapy over the winter break and almost immediately was prescribed Zoloft. I gained some weight at first but my mood steadily began to improve. I stopped wanting to self harm and I stopped fantasizing about suicide within a month. It fixed my inner clock as well, as I started being tired at normal times. This was difficult at first but beneficial in the long run."

   
10

ali78 December 19, 2017

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For Major Depressive Disorder "Saw no affect"

   
1.0

Needaxanax December 10, 2017

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For Depression "I was on Cipralex for 3 years and it destroyed my life. I lost 3 years of my life leaving school and doing nothing but sit at home worthless. Then I switched to Zoloft, I felt better on Zoloft but still the same complaint of being a “zombie”. I have never felt it is me for the past 10 years. I had tried getting off these drugs so many times but everytime I do it I feel better for the first few months then I collapse, again. It is very hard to be on them, and to be off them at the same time. My advice for you is to try them at last. Never start with antidepressants. Thank you and good luck."

   
5.0

Anonymous (taken for 10 years or more) December 9, 2017

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For Post Traumatic Stress Disorder "MIGRAINE SUFFERERS BEWARE: this medication took my migraine condition to another level of pain and frequency. The worst part is that my doctor did not share with me that Zoloft can make migraines worse before I started the medication. I had at least 2-3 days every week that not only was I completely incapacitated by the pain of them (something typical with migraines) to the point that I could not go to class, but the vomiting and nausea was relentless. I lost 15 pounds on this medication after taking it for just 6 weeks because of the vomiting from migraines. I went to the hospital toward the end of trying Zoloft because of dehydration and the worst pain I've felt in my life from the migraines this caused. be careful if you have migraines"

   
2.0

ptsd patient (taken for 1 to 6 months) November 21, 2017

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For Social Anxiety Disorder "If your scared to try something new I completely understand! I was really nervous about trying Zoloft, but I have to say I'm happy I did! I've only been taking it for a week for my anxiety disorder, stress, ptsd and depression. It has helped me feel more balanced and I'm a lot more calm. I'm happier and I can tell it helps me not have so many negative thoughts that bring on my anxiety about things. I can tell it's helping become a better mom and wife already. I hope it continues to work for me, because I was under a lot of stress and always worrying about stuff and I couldn't take the way I felt anymore. I had nausea and dizziness like the first 2 days, but then it went away. Stick with it if you want to see a difference! :)"

   
9.0

Anonymous (taken for less than 1 month) November 17, 2017

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For Social Anxiety Disorder "My Doctor prescribed this for anxiety. 10mg. Although it seemed to help my physical affects of anxiety it made everything else much worse. Tired, anxious, head aches, brain zaps, ringing in ears, spacey, edgy, and not myself at all. I was turning into a walking zombie. It was awful. I couldn't tell if it was my anxiety or the side effects. I thought I was going crazy for 6 months. I finally talked to a Therapist and he took me off of Zoloft and put me on Lexapro. Which was much better but still pretty awful. I finally found the courage to ween myself off over a period of two months and I feel GREAT! So thankful to be myself again. Please make sure you really need to be on these before you take them. Do your research and good luck!"

   
1.0

vincent zoloft bad (taken for 6 months to 1 year) November 17, 2017

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For Post Traumatic Stress Disorder "Military Combat veteran with previous history of trauma. After ten years of talk therapy, Zoloft cut panic attacks almost to nothing, also brought about a lot of memories, and real therapy finally began. Erectile dysfunction curbed with Buruprion daily and Viagra for intercourse. It took 4 days for side effects to wear off, it took about three months for therapeutic benefits - went back to school, made friends, found a girlfriend etc."

   
9.0

Frost1232 November 10, 2017

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For Postpartum Depression "I was prescribed Zoloft for postpartum depression, anxiety and OCD of contamination. I took 10mg of Zoloft for two weeks only as it was ineffective for me. I experienced no side effects, which was the only upside. All medications work differently for different people. I experienced postpartum depression and anxiety only one month after my first and only son was born. As a first time mom I thought everything I was experiencing was typical, until I began having suicidal thoughts and resorted to self harm all taking a toll on my relationship with my son and husband. Waited until my son was 10 months old to finally get help. I felt severe anxiety still while taking Zoloft. Again this is only my experience with this medication."

   
5.0

Mamanainteasy November 8, 2017

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For Panic Disorder "Came off Opioids in March after taking them for 2 years till I had my hip replaced. The anxiety and depression I experienced post the pain medication was horrific. I had no idea that I would become suicidal because of stopping opioids but I did. Every morning I awoke with the most intense panic and major depression which lasted day after day after day because I hadn’t been producing my own dopamine or serotonin whilst on pain meds. I thought I’d never recover. I stuck it out for two months when I got to the point of truly fearing for my life and afraid for my sanity. My doc was fantastic and very understanding. It’s only coming to light now the dangers of opioids, anyway I started on Zoloft and I’m feeling so much better again. Thank Goodness!"

CL77 (taken for 1 to 6 months) November 6, 2017

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For Depression "I was prescribed this a couple of months ago for severe anxiety and postpartum depression after an ectopic pregnancy. I felt euphoric for the first few days, and was literally awake for over 48 hours straight. But after the initial side effects wore off I was so thankful for this meditation. I was always against antidepressants and believed I could just 'get over it' with my mind...but after losing the baby my anxiety was through the roof and I couldn't function like a normal person. I'd come home from work and hide in my room away from my family, I avoided leaving the house unless I absolutely had to, I'd spend all day exhausting myself. I now feel more like myself than I have in years."

   
8.0

KatieQ (taken for 1 to 6 months) October 28, 2017

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For Panic Disorder "I was on Zoloft for a few years as I have generalized anxiety disorder. I am also somewhat ADD and suffer from chronic insomnia but no depression. It helped but I got a new doctor and we decided to try Wellbutrin and vyvance respectively to treat the ADD. Wellbutrin actually made me depressed and the vyvance did wonders for the ADD but horrible for anxiety. E We then tried Effexor. Not the one. I went back begging for my Zoloft and a clonazepam at night. By far the best drug for me. It does take a couple of weeks before it calms me down enough to sleep. Being back on it feels like coming home again!"

   
9.0

Miss clairol (taken for 1 to 2 years) October 23, 2017

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For Social Anxiety Disorder "I thought I would share today my experience with zoloft. 2 months ago I was the anxious one on here reading all the reviews on medications, every one and there was positive and negatives. So worried about taking an "antidepressant". I suffered daily with SEVERE anxiety and panic attacks to where I would have a panic attack sometimes for a few hours. It was awful. And because I felt like that so often I would say I had mild depression. Just hopeless. Could anything help my anxiety ? This medicine has changed my life for the better. I started at 25mg and still felt bad, no improvement even after 5 weeks. My doctor upped me to 50mg and within a week I felt 100x better. I had no side effects other than 2/3 headaches. My advice to you, try it."

   
10

Anonymous (taken for 1 to 6 months) October 17, 2017

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For Major Depressive Disorder "I’ve suffered from serious depression since I was about 11 but always refused treatment because I’m against any kind drugs and I was afraid I would lose myself and become a zombie instead and I didn’t want that. But now in my 30’s now and feeling very suicidal, waking up anxious everyday, heart racing non stop, always crying and not being able to do anything really without being panicky and ridiculously self conscious, relationship failing because of my head, I was at the end. Started on 25mg of zoloft and from first day no crying. No depression or anxiety, no reactive emotions anymore. From first day. Didn’t think it would work from first day but it has and I’m blown away I didn’t start this sooner. Side effect( very tired though ) definitely worth it."

   
10

Saltgirl22 October 10, 2017

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For Depression "This med helps me depression so much! I have severe depression and anxiety and it helps with everything - the sadness, irritability, anxiety, social anxiety, you name it. Unfortunately it causes major weight gain. I mean, I gained 40 lbs in a few months so I weaned off of it, lost the weight with no lifestyle changes. Tried other meds but nothing worked as well so I have it another try. Again, weight gain. No lifestyle changes and gained 70lbs in 4 months. Repeat weaning. Repeat weight loss. Became suicidal. Had to go back on the med. remained on it for 9 years gained 150 lbs and remained stable there. Recently went off again and I'm trying to find another med because I can't handle obesity but can't find another med that works as well!"

   
9.0

Depressedmomof1 October 10, 2017

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For Major Depressive Disorder "I am 73 years old and have been on Zoloft (generic version) since 1990 when I began seeing a Rheumatologist for Rheumatic Fever. My depression was caused by childhood sexual abuse which my mind had locked away until this time of illness. I was also very angry and contemplated suicide. I could not share my story because of shame and the stigma. She saw I was sad and depressed and wrote a script for Zoloft which I have been on it ever since. Started with 50mgs and now taking 100mgs. She saved my life and my sanity. I did go to counselling years later and was able to verbalize my feelings and forgive. I am thankful for having Rheumatic Fever which led me to this sweet doctor. No side effects that I know of."

   
10

great-grannie of one (taken for 10 years or more) October 8, 2017

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