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Medications for Obsessive Compulsive Disorder

Other names: Obsessive Compulsive Neurosis; OCD

An anxiety disorder characterised by recurrent, persistent obsessions or compulsions. Obsessions are the intrusive ideas, thoughts, or images that are experienced as senseless or repugnant. Compulsions are repetitive and seemingly purposeful behaviour which the individual generally recognises as senseless and from which the individual does not derive pleasure although it may provide a release from tension.

Drugs used to treat Obsessive Compulsive Disorder

The following list of medications are in some way related to or used in the treatment of this condition.

Drug name Rating Reviews Activity ? Rx/OTC Pregnancy CSA Alcohol
Zoloft 7.9 135 reviews
Rx C N X

Generic name: sertraline systemic

Drug class: selective serotonin reuptake inhibitors

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

sertraline 7.8 240 reviews
Rx C N X

Generic name: sertraline systemic

Brand name:  Zoloft

Drug class: selective serotonin reuptake inhibitors

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

Prozac 7.9 107 reviews
Rx C N X

Generic name: fluoxetine systemic

Drug class: selective serotonin reuptake inhibitors

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

fluvoxamine 7.2 189 reviews
Rx C N X

Generic name: fluvoxamine systemic

Drug class: selective serotonin reuptake inhibitors

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

fluoxetine 7.8 166 reviews
Rx C N X

Generic name: fluoxetine systemic

Brand name:  Prozac

Drug class: selective serotonin reuptake inhibitors

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

clomipramine 8.0 170 reviews
Rx C N X

Generic name: clomipramine systemic

Brand name:  Anafranil

Drug class: tricyclic antidepressants

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

clonazepam Off-label 9.0 13 reviews
Rx D 4 X

Generic name: clonazepam systemic

Drug class: benzodiazepines, benzodiazepine anticonvulsants

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

Off-label: Yes

escitalopram Off-label 8.2 112 reviews
Rx C N X

Generic name: escitalopram systemic

Drug class: selective serotonin reuptake inhibitors

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

Off-label: Yes

Anafranil 8.1 65 reviews
Rx C N X

Generic name: clomipramine systemic

Drug class: tricyclic antidepressants

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Paxil 7.3 31 reviews
Rx D N X

Generic name: paroxetine systemic

Drug class: selective serotonin reuptake inhibitors

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

quetiapine Off-label 8.6 43 reviews
Rx C N X

Generic name: quetiapine systemic

Drug class: atypical antipsychotics

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

Off-label: Yes

citalopram Off-label 7.5 38 reviews
Rx C N X

Generic name: citalopram systemic

Drug class: selective serotonin reuptake inhibitors

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

Off-label: Yes

tramadol Off-label 9.7 3 reviews
Rx C 4 X

Generic name: tramadol systemic

Drug class: narcotic analgesics

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

Off-label: Yes

paroxetine 7.0 44 reviews
Rx D N X

Generic name: paroxetine systemic

Brand names:  Paxil, Pexeva

Drug class: selective serotonin reuptake inhibitors

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

venlafaxine Off-label 7.6 35 reviews
Rx C N X

Generic name: venlafaxine systemic

Drug class: serotonin-norepinephrine reuptake inhibitors

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

Off-label: Yes

aripiprazole Off-label 7.1 30 reviews
Rx C N X

Generic name: aripiprazole systemic

Drug class: atypical antipsychotics

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

Off-label: Yes

mirtazapine Off-label 6.4 23 reviews
Rx C N X

Generic name: mirtazapine systemic

Drug class: tetracyclic antidepressants

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

Off-label: Yes

olanzapine Off-label 6.8 15 reviews
Rx C N X

Generic name: olanzapine systemic

Drug class: atypical antipsychotics

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

Off-label: Yes

ondansetron Off-label Rate Add review
Rx B N

Generic name: ondansetron systemic

Drug class: 5HT3 receptor antagonists

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

Off-label: Yes

ziprasidone Off-label 5.0 2 reviews
Rx C N X

Generic name: ziprasidone systemic

Drug class: atypical antipsychotics

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

Off-label: Yes

riluzole Off-label 8.5 4 reviews
Rx C N

Generic name: riluzole systemic

Drug class: miscellaneous central nervous system agents

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

Off-label: Yes

Pexeva Rate Add review
Rx D N X

Generic name: paroxetine systemic

Drug class: selective serotonin reuptake inhibitors

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

vilazodone Off-label 4.1 11 reviews
Rx C N X

Generic name: vilazodone systemic

Drug class: miscellaneous antidepressants

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

Off-label: Yes

Topics under Obsessive Compulsive Disorder

Legend

Rating For ratings, users were asked how effective they found the medicine while considering positive/adverse effects and ease of use (1 = not effective, 10 = most effective).
Activity Activity is based on recent site visitor activity relative to other medications in the list.
Rx Prescription only.
OTC Over-the-counter.
Rx/OTC Prescription or Over-the-counter.
Off-label This medication may not be approved by the FDA for the treatment of this condition.
EUA An Emergency Use Authorization (EUA) allows the FDA to authorize unapproved medical products or unapproved uses of approved medical products to be used in a declared public health emergency when there are no adequate, approved, and available alternatives.
Pregnancy Category
A Adequate and well-controlled studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).
B Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
C Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
D There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
X Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use in pregnant women clearly outweigh potential benefits.
N FDA has not classified the drug.
Controlled Substances Act (CSA) Schedule
M The drug has multiple schedules. The schedule may depend on the exact dosage form or strength of the medication.
U CSA Schedule is unknown.
N Is not subject to the Controlled Substances Act.
1 Has a high potential for abuse. Has no currently accepted medical use in treatment in the United States. There is a lack of accepted safety for use under medical supervision.
2 Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence.
3 Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence.
4 Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3.
5 Has a low potential for abuse relative to those in schedule 4. Has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 4.
Alcohol
X Interacts with Alcohol.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.