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Riluzole Dosage

Medically reviewed by Last updated on Jun 19, 2023.

Applies to the following strengths: 50 mg; 50 mg/10 mL

Usual Adult Dose for Amyotrophic Lateral Sclerosis

50 mg orally every 12 hours


Use: For the treatment of amyotrophic lateral sclerosis.

Renal Dose Adjustments

Use with caution

Liver Dose Adjustments

Not recommended in patients with baseline elevations of serum aminotransferases greater than 5 times the upper limit of normal or evidence of liver dysfunction (e.g. elevated bilirubin)

Discontinue therapy if hepatic transaminases increase to greater than 5 x ULN
Discontinue therapy if there is evidence of liver dysfunction (e.g. elevated bilirubin)



Safety and efficacy have not been established in patients younger than 18 years.

Consult WARNINGS section for additional precautions.


Data not available.

Other Comments

Administration advice:

Oral Suspension:



Patient advice:

Frequently asked questions

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.