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Rilutek

Generic Name: riluzole (RIL yoo zol)
Brand Name: Rilutek, Tiglutik

Medically reviewed by Drugs.com on Feb 27, 2019 – Written by Cerner Multum

What is Rilutek?

Rilutek is used to treat amyotrophic lateral sclerosis, also known as ALS or Lou Gehrig's disease.

Rilutek is not a cure for ALS, but it may delay progression of the disease and prolong your life.

Rilutek may also be used for purposes not listed in this medication guide.

Important Information

Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.

Before taking this medicine

You should not use Rilutek if you are allergic to it.

Rilutek is not approved for use by anyone younger than 18 years old.

Tell your doctor if you have ever had:

Rilutek may harm an unborn baby. Use effective birth control to prevent pregnancy, and tell your doctor if you become pregnant.

It may not be safe to breastfeed while using Rilutek. Ask your doctor about any risk.

How should I take Rilutek?

Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

Take Rilutek on an empty stomach, at least 1 hour before or 2 hours after a meal.

Read and carefully follow any Instructions for Use provided with your medicine. Ask your doctor or pharmacist if you do not understand these instructions.

Shake the oral suspension (liquid) before you measure a dose. Use the dosing syringe provided, or use a medicine dose-measuring device (not a kitchen spoon).

You will need frequent medical tests.

Store at room temperature away from moisture, heat, and light. Keep the liquid medicine upright and do not freeze. Throw away any unused liquid after 15 days.

What happens if I miss a dose?

Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include drowsiness, confusion, problems with thinking or memory, tremors, or blue lips or fingers.

What should I avoid while taking Rilutek?

Avoid smoking. Smoking cigarettes may make Rilutek less effective.

What are the Rilutek side effects of riluzole?

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Stop using Rilutek and call your doctor at once if you have:

  • sudden chest pain, wheezing, feeling short of breath;

  • dry cough, or cough with mucus;

  • low white blood cell counts--fever, mouth sores, skin sores, sore throat; or

  • liver problems--nausea, loss of appetite, stomach pain (upper right side), tiredness, itching, dark urine, jaundice (yellowing of the skin or eyes).

Side effects may be more likely to occur in people of Japanese descent.

Common side effects may include:

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Rilutek?

Sometimes it is not safe to use certain medications at the same time. Some drugs can affect your blood levels of other drugs you take, which may increase side effects or make the medications less effective.

Rilutek can harm your liver, especially if you also use certain medicines for infections, high cholesterol, seizures, birth control, hormone replacement, or pain or arthritis (including Tylenol, Advil, and Aleve).

Other drugs may affect Rilutek, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.

Further information

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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