Skip to main content

Medications for Seizures

Other names: Absence Seizure; Complex Partial Seizure; convulsion; Fits

Medically reviewed by Carmen Pope, BPharm. Last updated on Jan 18, 2024.

Anti-seizure medications can help prevent or stop seizures. The choice depends on the type of seizure, the age of the person, the potential side effects of the medication, other medications they may be taking, or concurrent health conditions. 

Various seizure types

Focal seizures


Focal and generalized seizures

Focal and epileptic spasms

Absence seizures

Infantile spasms

Drugs used to treat Seizures

The following list of medications are in some way related to or used in the treatment of this condition.

Filter
Drug name Rating Reviews Activity ? Rx/OTC Pregnancy CSA Alcohol
Keppra 5.6 191 reviews for Keppra to treat Seizures
Rx C N X
Generic name:
levetiracetam systemic
Drug class:
pyrrolidine anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
levetiracetam 5.9 245 reviews for levetiracetam to treat Seizures
Rx C N X
Generic name:
levetiracetam systemic
Brand names:
Keppra, Keppra XR, Elepsia XR, Roweepra, Roweepra XR, Spritam
Drug class:
pyrrolidine anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Diastat 7.0 1 review for Diastat to treat Seizures
Rx D 4 X
Generic name:
diazepam systemic
Drug class:
benzodiazepine anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Briviact 6.7 21 reviews for Briviact to treat Seizures
Rx C 5 X
Generic name:
brivaracetam systemic
Drug class:
pyrrolidine anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Dilantin 7.4 40 reviews for Dilantin to treat Seizures
Rx D N X
Generic name:
phenytoin systemic
Drug class:
hydantoin anticonvulsants, group I antiarrhythmics
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Vimpat 6.7 138 reviews for Vimpat to treat Seizures
Rx C 5 X
Generic name:
lacosamide systemic
Drug class:
miscellaneous anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Xcopri 8.6 18 reviews for Xcopri to treat Seizures
Rx 5 X
Generic name:
cenobamate systemic
Drug class:
carbamate anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Nayzilam 10 2 reviews for Nayzilam to treat Seizures
Rx D 4 X
Generic name:
midazolam systemic
Drug class:
benzodiazepines
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Valtoco Rate Add review
Rx D 4 X
Generic name:
diazepam systemic
Drug class:
benzodiazepine anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
brivaracetam 6.3 24 reviews for brivaracetam to treat Seizures
Rx C 5 X
Generic name:
brivaracetam systemic
Brand name:
Briviact
Drug class:
pyrrolidine anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
cenobamate 8.3 19 reviews for cenobamate to treat Seizures
Rx 5 X
Generic name:
cenobamate systemic
Brand name:
Xcopri
Drug class:
carbamate anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
clobazam Rate Add review
Rx C 4 X
Generic name:
clobazam systemic
Drug class:
benzodiazepines, benzodiazepine anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
rufinamide Rate Add review
Rx C N X
Generic name:
rufinamide systemic
Drug class:
dibenzazepine anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
phenobarbital 8.9 25 reviews for phenobarbital to treat Seizures
Rx D 4 X
Generic name:
phenobarbital systemic
Brand name:
Sezaby
Drug class:
barbiturates, barbiturate anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
zonisamide 5.3 86 reviews for zonisamide to treat Seizures
Rx C N X
Generic name:
zonisamide systemic
Brand names:
Zonegran, Zonisade
Drug class:
carbonic anhydrase inhibitor anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Trileptal 7.4 22 reviews for Trileptal to treat Seizures
Rx C N X
Generic name:
oxcarbazepine systemic
Drug class:
dibenzazepine anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
diazepam 9.1 14 reviews for diazepam to treat Seizures
Rx D 4 X
Generic name:
diazepam systemic
Brand names:
Diastat, Valtoco, Valium, Diastat AcuDial, Diazepam Intensol, Diastat Pediatric
Drug class:
benzodiazepines, benzodiazepine anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
oxcarbazepine 7.7 36 reviews for oxcarbazepine to treat Seizures
Rx C N X
Generic name:
oxcarbazepine systemic
Brand names:
Trileptal, Oxtellar XR
Drug class:
dibenzazepine anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
phenytoin 7.3 55 reviews for phenytoin to treat Seizures
Rx D N X
Generic name:
phenytoin systemic
Brand names:
Dilantin, Phenytoin Sodium, Phenytek
Drug class:
hydantoin anticonvulsants, group I antiarrhythmics
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
topiramate 6.3 22 reviews for topiramate to treat Seizures
Rx D N X
Generic name:
topiramate systemic
Brand names:
Topamax, Trokendi XR, Qudexy XR, Eprontia
Drug class:
carbonic anhydrase inhibitor anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Zonegran 6.4 42 reviews for Zonegran to treat Seizures
Rx C N X
Generic name:
zonisamide systemic
Drug class:
carbonic anhydrase inhibitor anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Keppra XR 7.4 9 reviews for Keppra XR to treat Seizures
Rx C N X
Generic name:
levetiracetam systemic
Drug class:
pyrrolidine anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
valproic acid 7.8 4 reviews for valproic acid to treat Seizures
Rx D N X
Generic name:
valproic acid systemic
Brand name:
Valproate Sodium
Drug class:
fatty acid derivative anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Topamax 4.9 8 reviews for Topamax to treat Seizures
Rx D N X
Generic name:
topiramate systemic
Drug class:
carbonic anhydrase inhibitor anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Valium 9.8 4 reviews for Valium to treat Seizures
Rx D 4 X
Generic name:
diazepam systemic
Drug class:
benzodiazepines, benzodiazepine anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information

Frequently asked questions

View more FAQ

Topics under Seizures

Legend

Rating For ratings, users were asked how effective they found the medicine while considering positive/adverse effects and ease of use (1 = not effective, 10 = most effective).
Activity Activity is based on recent site visitor activity relative to other medications in the list.
Rx Prescription only.
OTC Over-the-counter.
Rx/OTC Prescription or Over-the-counter.
Off-label This medication may not be approved by the FDA for the treatment of this condition.
EUA An Emergency Use Authorization (EUA) allows the FDA to authorize unapproved medical products or unapproved uses of approved medical products to be used in a declared public health emergency when there are no adequate, approved, and available alternatives.
Expanded Access Expanded Access is a potential pathway for a patient with a serious or immediately life-threatening disease or condition to gain access to an investigational medical product (drug, biologic, or medical device) for treatment outside of clinical trials when no comparable or satisfactory alternative therapy options are available.
Pregnancy Category
A Adequate and well-controlled studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).
B Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
C Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
D There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
X Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use in pregnant women clearly outweigh potential benefits.
N FDA has not classified the drug.
Controlled Substances Act (CSA) Schedule
M The drug has multiple schedules. The schedule may depend on the exact dosage form or strength of the medication.
U CSA Schedule is unknown.
N Is not subject to the Controlled Substances Act.
1 Has a high potential for abuse. Has no currently accepted medical use in treatment in the United States. There is a lack of accepted safety for use under medical supervision.
2 Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence.
3 Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence.
4 Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3.
5 Has a low potential for abuse relative to those in schedule 4. Has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 4.
Alcohol
X Interacts with Alcohol.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.