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Medications for Seizure Prevention (Seizure Prophylaxis)

Measures taken to prevent a seizure - an episode of abnormal electrical activity in the brain where a person's body may shake rapidly and uncontrollably.

Drugs used for Seizure Prevention

The following list of medications are in some way related to or used in the treatment of this condition.

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Drug name Rating Reviews Activity ? Rx/OTC Pregnancy CSA Alcohol
Lamictal 7.0 54 reviews for Lamictal to treat Seizure Prevention
Rx C N X
Generic name:
lamotrigine systemic
Drug class:
triazine anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
lamotrigine 7.2 93 reviews for lamotrigine to treat Seizure Prevention
Rx C N X
Generic name:
lamotrigine systemic
Brand names:
Lamictal, Lamictal XR, Lamictal ODT, Lamictal CD, Subvenite
Drug class:
triazine anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Topamax 5.8 43 reviews for Topamax to treat Seizure Prevention
Rx D N X
Generic name:
topiramate systemic
Drug class:
carbonic anhydrase inhibitor anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
clonazepam 8.6 62 reviews for clonazepam to treat Seizure Prevention
Rx D 4 X
Generic name:
clonazepam systemic
Brand name:
Klonopin
Drug class:
benzodiazepines, benzodiazepine anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
topiramate 5.9 70 reviews for topiramate to treat Seizure Prevention
Rx D N X
Generic name:
topiramate systemic
Brand names:
Topamax, Trokendi XR, Qudexy XR, Eprontia
Drug class:
carbonic anhydrase inhibitor anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Klonopin 8.1 27 reviews for Klonopin to treat Seizure Prevention
Rx D 4 X
Generic name:
clonazepam systemic
Drug class:
benzodiazepines, benzodiazepine anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
diazepam 9.0 6 reviews for diazepam to treat Seizure Prevention
Rx D 4 X
Generic name:
diazepam systemic
Brand name:
Valium
Drug class:
benzodiazepines, benzodiazepine anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Lamictal XR 9.0 3 reviews for Lamictal XR to treat Seizure Prevention
Rx C N X
Generic name:
lamotrigine systemic
Drug class:
triazine anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
valproic acid 5.8 5 reviews for valproic acid to treat Seizure Prevention
Rx D N X
Generic name:
valproic acid systemic
Brand name:
Valproate Sodium
Drug class:
fatty acid derivative anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Valium 8.3 3 reviews for Valium to treat Seizure Prevention
Rx D 4 X
Generic name:
diazepam systemic
Drug class:
benzodiazepines, benzodiazepine anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Epsom Salt Rate Add review
Rx/OTC D N
Generic name:
magnesium sulfate systemic
Drug class:
laxatives, minerals and electrolytes, miscellaneous anticonvulsants
For consumers:
dosage, interactions, side effects
magnesium sulfate 1.5 2 reviews for magnesium sulfate to treat Seizure Prevention
Rx/OTC D N
Generic name:
magnesium sulfate systemic
Brand name:
Epsom Salt
Drug class:
laxatives, minerals and electrolytes, miscellaneous anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Trokendi XR 10 1 review for Trokendi XR to treat Seizure Prevention
Rx D N X
Generic name:
topiramate systemic
Drug class:
carbonic anhydrase inhibitor anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Lamictal ODT Rate Add review
Rx C N X
Generic name:
lamotrigine systemic
Drug class:
triazine anticonvulsants
For consumers:
dosage, interactions, side effects
Lamictal CD Rate Add review
Rx C N X
Generic name:
lamotrigine systemic
Drug class:
triazine anticonvulsants
For consumers:
dosage, interactions, side effects
Subvenite Rate Add review
Rx C N X
Generic name:
lamotrigine systemic
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
acetazolamide 6.5 2 reviews for acetazolamide to treat Seizure Prevention
Rx C N
Generic name:
acetazolamide systemic
Drug class:
carbonic anhydrase inhibitors, carbonic anhydrase inhibitor anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
clorazepate 5.0 1 review for clorazepate to treat Seizure Prevention
Rx N 4 X
Generic name:
clorazepate systemic
Brand names:
Tranxene, Tranxene T-Tab
Drug class:
benzodiazepines
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Qudexy XR 1.0 1 review for Qudexy XR to treat Seizure Prevention
Rx D N X
Generic name:
topiramate systemic
Drug class:
carbonic anhydrase inhibitor anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Tranxene 5.0 1 review for Tranxene to treat Seizure Prevention
Rx N 4 X
Generic name:
clorazepate systemic
Drug class:
benzodiazepines
For consumers:
dosage, interactions, side effects
Eprontia Rate Add review
Rx D N X
Generic name:
topiramate systemic
Drug class:
carbonic anhydrase inhibitor anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Sabril Rate Add review
Rx C N X
Generic name:
vigabatrin systemic
Drug class:
gamma-aminobutyric acid analogs
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Tranxene T-Tab Rate Add review
Rx N 4 X
Generic name:
clorazepate systemic
Drug class:
benzodiazepines
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Valproate Sodium Rate Add review
Rx D N X
Generic name:
valproic acid systemic
For consumers:
dosage, interactions, side effects
vigabatrin Rate Add review
Rx C N X
Generic name:
vigabatrin systemic
Brand names:
Sabril, Vigadrone
Drug class:
gamma-aminobutyric acid analogs
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information

Frequently asked questions

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Rating For ratings, users were asked how effective they found the medicine while considering positive/adverse effects and ease of use (1 = not effective, 10 = most effective).
Activity Activity is based on recent site visitor activity relative to other medications in the list.
Rx Prescription only.
OTC Over-the-counter.
Rx/OTC Prescription or Over-the-counter.
Off-label This medication may not be approved by the FDA for the treatment of this condition.
EUA An Emergency Use Authorization (EUA) allows the FDA to authorize unapproved medical products or unapproved uses of approved medical products to be used in a declared public health emergency when there are no adequate, approved, and available alternatives.
Expanded Access Expanded Access is a potential pathway for a patient with a serious or immediately life-threatening disease or condition to gain access to an investigational medical product (drug, biologic, or medical device) for treatment outside of clinical trials when no comparable or satisfactory alternative therapy options are available.
Pregnancy Category
A Adequate and well-controlled studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).
B Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
C Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
D There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
X Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use in pregnant women clearly outweigh potential benefits.
N FDA has not classified the drug.
Controlled Substances Act (CSA) Schedule
M The drug has multiple schedules. The schedule may depend on the exact dosage form or strength of the medication.
U CSA Schedule is unknown.
N Is not subject to the Controlled Substances Act.
1 Has a high potential for abuse. Has no currently accepted medical use in treatment in the United States. There is a lack of accepted safety for use under medical supervision.
2 Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence.
3 Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence.
4 Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3.
5 Has a low potential for abuse relative to those in schedule 4. Has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 4.
Alcohol
X Interacts with Alcohol.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.