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Medications for Seizure Prevention (Seizure Prophylaxis)

Measures taken to prevent a seizure - an episode of abnormal electrical activity in the brain where a person's body may shake rapidly and uncontrollably.

Drugs used for Seizure Prevention

The following list of medications are in some way related to or used in the treatment of this condition.

Drug name Rating Reviews Activity ? Rx/OTC Pregnancy CSA Alcohol
Lamictal 7.0 51 reviews
Rx C N X

Generic name: lamotrigine systemic

Drug class: triazine anticonvulsants

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

topiramate 5.9 70 reviews
Rx D N X

Generic name: topiramate systemic

Brand names:  Topamax, Trokendi XR, Qudexy XR

Drug class: carbonic anhydrase inhibitor anticonvulsants

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

lamotrigine 7.2 85 reviews
Rx C N X

Generic name: lamotrigine systemic

Brand names:  Lamictal, Lamictal XR, Lamictal ODT, Lamictal CD …show all

Drug class: triazine anticonvulsants

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

Topamax 5.8 43 reviews
Rx D N X

Generic name: topiramate systemic

Drug class: carbonic anhydrase inhibitor anticonvulsants

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

clonazepam 8.5 59 reviews
Rx D 4 X

Generic name: clonazepam systemic

Brand name:  Klonopin

Drug class: benzodiazepines, benzodiazepine anticonvulsants

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

diazepam 9.0 6 reviews
Rx D 4 X

Generic name: diazepam systemic

Brand name:  Valium

Drug class: benzodiazepines, benzodiazepine anticonvulsants

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

Klonopin 8.1 25 reviews
Rx D 4 X

Generic name: clonazepam systemic

Drug class: benzodiazepines, benzodiazepine anticonvulsants

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Trokendi XR 10 1 review
Rx D N X

Generic name: topiramate systemic

Drug class: carbonic anhydrase inhibitor anticonvulsants

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Sabril Rate Add review
Rx C N X

Generic name: vigabatrin systemic

Drug class: gamma-aminobutyric acid analogs

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

vigabatrin Rate Add review
Rx C N X

Generic name: vigabatrin systemic

Brand names:  Sabril, Vigadrone

Drug class: gamma-aminobutyric acid analogs

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

Lamictal XR 8.5 2 reviews
Rx C N X

Generic name: lamotrigine systemic

Drug class: triazine anticonvulsants

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

valproic acid 5.0 4 reviews
Rx D N X

Generic name: valproic acid systemic

Drug class: fatty acid derivative anticonvulsants

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Valium 8.3 3 reviews
Rx D 4 X

Generic name: diazepam systemic

Drug class: benzodiazepines, benzodiazepine anticonvulsants

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Epsom Salt Rate Add review
Rx/OTC D N

Generic name: magnesium sulfate systemic

Drug class: laxatives, minerals and electrolytes, miscellaneous anticonvulsants

For consumers: dosage, interactions, side effects

magnesium sulfate 1.5 2 reviews
Rx/OTC D N

Generic name: magnesium sulfate systemic

Brand name:  Epsom Salt

Drug class: laxatives, minerals and electrolytes, miscellaneous anticonvulsants

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

Lamictal ODT Rate Add review
Rx C N X

Generic name: lamotrigine systemic

Drug class: triazine anticonvulsants

For consumers: dosage, interactions, side effects

Diamox Rate Add review
Rx C N

Generic name: acetazolamide systemic

Drug class: carbonic anhydrase inhibitors, carbonic anhydrase inhibitor anticonvulsants

For consumers: dosage, interactions, side effects

acetazolamide 6.5 2 reviews
Rx C N

Generic name: acetazolamide systemic

Brand names:  Diamox, Diamox Sequels

Drug class: carbonic anhydrase inhibitors, carbonic anhydrase inhibitor anticonvulsants

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

clorazepate 5.0 1 review
Rx N 4 X

Generic name: clorazepate systemic

Brand names:  Tranxene, Tranxene T-Tab

Drug class: benzodiazepines

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

Lamictal CD Rate Add review
Rx C N X

Generic name: lamotrigine systemic

Drug class: triazine anticonvulsants

For consumers: dosage, interactions, side effects

Qudexy XR 1.0 1 review
Rx D N X

Generic name: topiramate systemic

Drug class: carbonic anhydrase inhibitor anticonvulsants

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Tranxene 5.0 1 review
Rx N 4 X

Generic name: clorazepate systemic

Drug class: benzodiazepines

For consumers: dosage, interactions, side effects

Diamox Sequels Rate Add review
Rx C N

Generic name: acetazolamide systemic

Drug class: carbonic anhydrase inhibitors, carbonic anhydrase inhibitor anticonvulsants

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Tranxene T-Tab Rate Add review
Rx N 4 X

Generic name: clorazepate systemic

Drug class: benzodiazepines

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Vigadrone Rate Add review
Rx C N X

Generic name: vigabatrin systemic

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Frequently asked questions

Learn more about Seizure Prevention

Care guides

Symptoms and treatments

Legend

Rating For ratings, users were asked how effective they found the medicine while considering positive/adverse effects and ease of use (1 = not effective, 10 = most effective).
Activity Activity is based on recent site visitor activity relative to other medications in the list.
Rx Prescription only.
OTC Over-the-counter.
Rx/OTC Prescription or Over-the-counter.
Off-label This medication may not be approved by the FDA for the treatment of this condition.
EUA An Emergency Use Authorization (EUA) allows the FDA to authorize unapproved medical products or unapproved uses of approved medical products to be used in a declared public health emergency when there are no adequate, approved, and available alternatives.
Pregnancy Category
A Adequate and well-controlled studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).
B Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
C Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
D There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
X Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use in pregnant women clearly outweigh potential benefits.
N FDA has not classified the drug.
Controlled Substances Act (CSA) Schedule
M The drug has multiple schedules. The schedule may depend on the exact dosage form or strength of the medication.
U CSA Schedule is unknown.
N Is not subject to the Controlled Substances Act.
1 Has a high potential for abuse. Has no currently accepted medical use in treatment in the United States. There is a lack of accepted safety for use under medical supervision.
2 Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence.
3 Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence.
4 Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3.
5 Has a low potential for abuse relative to those in schedule 4. Has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 4.
Alcohol
X Interacts with Alcohol.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.