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Medications for Seizure Prevention (Seizure Prophylaxis)

What is Seizure Prevention:  Measures taken to prevent a seizure - an episode of abnormal electrical activity in the brain where a person's body may shake rapidly and uncontrollably.

Medications to treat Seizure Prevention

The following list of medications are in some way related to, or used in the treatment of this condition.

Drug name Rx / OTC Pregnancy CSA Alcohol Reviews Rating Popularity
Lamictal Rx C N X 43 reviews
7.0

Generic name: lamotrigine systemic

Drug class: triazine anticonvulsants

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

 
Topamax Rx D N X 33 reviews
6.0

Generic name: topiramate systemic

Drug class: carbonic anhydrase inhibitor anticonvulsants

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

 
lamotrigine Rx C N X 66 reviews
7.0

Generic name: lamotrigine systemic

Brand names:  Lamictal, Lamictal XR, Lamictal ODT, Lamictal CD …

Drug class: triazine anticonvulsants

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

 
Klonopin Rx D 4 X 13 reviews
8.0

Generic name: clonazepam systemic

Drug class: benzodiazepines, benzodiazepine anticonvulsants

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

 
clonazepam Rx D 4 X 39 reviews
8.0

Generic name: clonazepam systemic

Brand name:  Klonopin

Drug class: benzodiazepines, benzodiazepine anticonvulsants

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

 
topiramate Rx D N X 53 reviews
6.0

Generic name: topiramate systemic

Brand names:  Topamax, Topiragen, Trokendi XR, Topamax Sprinkle, Qudexy XR …

Drug class: carbonic anhydrase inhibitor anticonvulsants

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

 
Lamictal XR Rx C N X 2 reviews
9.0

Generic name: lamotrigine systemic

Drug class: triazine anticonvulsants

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

 
Valium Rx D 4 X 3 reviews
8.0

Generic name: diazepam systemic

Drug class: benzodiazepines, benzodiazepine anticonvulsants

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

 
diazepam Rx D 4 X 3 reviews
8.0

Generic name: diazepam systemic

Brand names:  Valium, Diazepam Intensol, Diastat, Diastat AcuDial, Diastat Pediatric …

Drug class: benzodiazepines, benzodiazepine anticonvulsants

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

 
Diazepam Intensol Rx D 4 X Add review
9.0

Generic name: diazepam systemic

Drug class: benzodiazepines, benzodiazepine anticonvulsants

For consumers: dosage, interactions, side effects

 
valproic acid Rx D N X 3 reviews
4.0

Generic name: valproic acid systemic

Brand names:  Depacon, Depakene

Drug class: fatty acid derivative anticonvulsants

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, Prescribing Information

 
Depacon Rx D N X Add review Add

Generic name: valproic acid systemic

Drug class: fatty acid derivative anticonvulsants

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

 
Depakene Rx D N X 2 reviews
1.0

Generic name: valproic acid systemic

Drug class: fatty acid derivative anticonvulsants

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

 
Epsom Salt Rx/OTC D N Add review Add

Generic name: magnesium sulfate systemic

Drug class: laxatives, minerals and electrolytes, miscellaneous anticonvulsants

For consumers: dosage, interactions, side effects

 
Lamictal ODT Rx C N X Add review
10

Generic name: lamotrigine systemic

Drug class: triazine anticonvulsants

For consumers: dosage, interactions, side effects

 
Diamox Rx C N Add review Add

Generic name: acetazolamide systemic

Drug class: carbonic anhydrase inhibitors, carbonic anhydrase inhibitor anticonvulsants

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

 
Diastat Rx D 4 X Add review Add

Generic name: diazepam systemic

Drug class: benzodiazepines, benzodiazepine anticonvulsants

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

 
magnesium sulfate Rx/OTC D N 1 review
1.0

Generic name: magnesium sulfate systemic

Brand name:  Epsom Salt

Drug class: laxatives, minerals and electrolytes, miscellaneous anticonvulsants

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

 
Topiragen Rx D N X 1 review
9.0

Generic name: topiramate systemic

Drug class: carbonic anhydrase inhibitor anticonvulsants

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

 
Tranxene Rx N 4 X 1 review
5.0

Generic name: clorazepate systemic

Drug class: benzodiazepines

For consumers: dosage, interactions, side effects

 
Trokendi XR Rx D N X 1 review
8.0

Generic name: topiramate systemic

Drug class: carbonic anhydrase inhibitor anticonvulsants

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

 
Diastat AcuDial Rx D 4 X Add review Add

Generic name: diazepam systemic

Drug class: benzodiazepines, benzodiazepine anticonvulsants

For consumers: dosage, interactions, side effects

 
Topamax Sprinkle Rx D N X Add review Add

Generic name: topiramate systemic

Drug class: carbonic anhydrase inhibitor anticonvulsants

For consumers: dosage, interactions, side effects

 
acetazolamide Rx C N 2 reviews
6.0

Generic name: acetazolamide systemic

Brand names:  Diamox, Diamox Sequels

Drug class: carbonic anhydrase inhibitors, carbonic anhydrase inhibitor anticonvulsants

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

 
clorazepate Rx N 4 X 1 review
6.0

Generic name: clorazepate systemic

Brand names:  Tranxene, Tranxene T-Tab

Drug class: benzodiazepines

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

 
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Legend

Off Label This medication may not be approved by the FDA for the treatment of this condition.
Prescription Only / Over the Counter
Rx Prescription Only
OTC Over the Counter
Rx/OTC Prescription or Over the Counter
Pregnancy
A Adequate and well-controlled studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).
B Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
C Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
D There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
X Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use in pregnant women clearly outweigh potential benefits.
N FDA has not classified the drug.
Controlled Substances Act Schedule
N Is not subject to the Controlled Substances Act.
1 Has a high potential for abuse. Has no currently accepted medical use in treatment in the United States. There is a lack of accepted safety for use under medical supervision.
2 Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence.
3 Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence.
4 Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3.
5 Has a low potential for abuse relative to those in schedule 4. Has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 4.
Alcohol
X Interacts with Alcohol.

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