Phenytoin Interactions
There are 857 drugs known to interact with phenytoin, along with 12 disease interactions, and 1 alcohol/food interaction. Of the total drug interactions, 243 are major, 568 are moderate, and 46 are minor.
- View all 857 medications that may interact with phenytoin
- View phenytoin alcohol/food interactions (1)
- View phenytoin disease interactions (12)
Most frequently checked interactions
View interaction reports for phenytoin and the medicines listed below.
- Acetylsalicylic Acid (aspirin)
- Advair Diskus (fluticasone / salmeterol)
- Aspirin Low Strength (aspirin)
- Ativan (lorazepam)
- Combivent (albuterol / ipratropium)
- Coumadin (warfarin)
- Cymbalta (duloxetine)
- Eliquis (apixaban)
- Fish Oil (omega-3 polyunsaturated fatty acids)
- Keppra (levetiracetam)
- Lantus (insulin glargine)
- Lasix (furosemide)
- Lexapro (escitalopram)
- Lipitor (atorvastatin)
- Lyrica (pregabalin)
- Metoprolol Succinate ER (metoprolol)
- Metoprolol Tartrate (metoprolol)
- MiraLAX (polyethylene glycol 3350)
- Neurontin (gabapentin)
- Nexium (esomeprazole)
- Paracetamol (acetaminophen)
- Plavix (clopidogrel)
- Seroquel (quetiapine)
- Synthroid (levothyroxine)
- Tylenol (acetaminophen)
- Vimpat (lacosamide)
- Vitamin B12 (cyanocobalamin)
- Vitamin C (ascorbic acid)
- Vitamin D2 (ergocalciferol)
- Vitamin D3 (cholecalciferol)
Phenytoin alcohol/food interactions
There is 1 alcohol/food interaction with phenytoin.
Phenytoin disease interactions
There are 12 disease interactions with phenytoin which include:
- blood dyscrasias
- liver disease
- porphyria
- renal dysfunction
- cardiotoxicity
- suicidal tendency
- arrhythmias
- hyperglycemia
- megaloblastic anemia
- osteomalacia
- alcoholism
- thyroid function tests
Report options
More about phenytoin
- phenytoin consumer information
- Compare alternatives
- Pricing & coupons
- Reviews (117)
- Drug images
- Side effects
- Dosage information
- During pregnancy
- Drug class: hydantoin anticonvulsants
- Breastfeeding
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
See also:
Levetiracetam
Levetiracetam systemic is used for bipolar disorder, epilepsy, hyperekplexia, neuralgia, new daily ...
Topiramate
Topiramate systemic is used for bipolar disorder, borderline personality disorder, bulimia ...
Ozempic
Learn about Ozempic (semaglutide) for type 2 diabetes treatment, weight management, cardiovascular ...
Diazepam
Diazepam is used to treat anxiety disorders, alcohol withdrawal symptoms, or muscle spasms. Learn ...
Pregabalin
Pregabalin may be used to treat certain types of pain and used in combination with other ...
Lorazepam
Lorazepam is in a group of drugs called benzodiazepines and is used to treat anxiety disorders ...
Clonazepam
Clonazepam is used to treat seizures and panic disorder. Learn about side effects, interactions and ...
Lamictal
Lamictal is an anti-epileptic medication used treat seizures in adults and children over 2 years ...
Lyrica
Lyrica is used to control seizures, treat nerve pain and fibromyalgia. Learn about side effects ...
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
