Topiramate Interactions
There are 291 drugs known to interact with topiramate, along with 8 disease interactions, and 1 alcohol/food interaction. Of the total drug interactions, 108 are major, 180 are moderate, and 3 are minor.
- View all 291 medications that may interact with topiramate
- View topiramate alcohol/food interactions (1)
- View topiramate disease interactions (8)
Most frequently checked interactions
View interaction reports for topiramate and the medicines listed below.
- Abilify (aripiprazole)
- Adderall (amphetamine / dextroamphetamine)
- Adderall XR (amphetamine / dextroamphetamine)
- Benadryl (diphenhydramine)
- Cymbalta (duloxetine)
- Fish Oil (omega-3 polyunsaturated fatty acids)
- Flexeril (cyclobenzaprine)
- Flonase (fluticasone nasal)
- Lexapro (escitalopram)
- Linzess (linaclotide)
- Lyrica (pregabalin)
- Metoprolol Succinate ER (metoprolol)
- Norco (acetaminophen / hydrocodone)
- Nurtec ODT (rimegepant)
- ProAir HFA (albuterol)
- Prozac (fluoxetine)
- Seroquel (quetiapine)
- Singulair (montelukast)
- Synthroid (levothyroxine)
- Tylenol (acetaminophen)
- Vitamin B12 (cyanocobalamin)
- Vitamin C (ascorbic acid)
- Vitamin D2 (ergocalciferol)
- Vitamin D3 (cholecalciferol)
- Vyvanse (lisdexamfetamine)
- Wellbutrin XL (bupropion)
- Xanax (alprazolam)
- Zofran (ondansetron)
- Zoloft (sertraline)
- Zyrtec (cetirizine)
Topiramate alcohol/food interactions
There is 1 alcohol/food interaction with topiramate.
Topiramate disease interactions
There are 8 disease interactions with topiramate which include:
- oligohidrosis/hyperthermia
- suicidal tendency
- renal dysfunction
- metabolic acidosis
- angle closure glaucoma
- hemodialysis
- liver disease
- nephrolithiasis
Report options
More about topiramate
- topiramate consumer information
- Compare alternatives
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- Reviews (1,333)
- Drug images
- Side effects
- Dosage information
- Patient tips
- During pregnancy
- Support group
- Drug class: carbonic anhydrase inhibitor anticonvulsants
- Breastfeeding
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
