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Fatty acid derivative anticonvulsants

What are Fatty acid derivative anticonvulsants?

Fatty acid derivative anticonvulsants appear to increase the availability of gamma-aminobutyric acid (GABA), an inhibitory neurotransmitter. They have several mechanisms of action. They have inhibitory action against GABA transaminase, which breaksdown GABA. This leads to increased concentration of GABA in the synapses. Other proposed mechanisms of action that account for their anticonvulsant properties is they either enhance the action of GABA or mimic its action at postsynaptic receptor sites. They also block voltage gated sodium channels and T-type calcium channels, and cause inhibitory activity in the brain.

Fatty acid derivatives are broad-spectrum anticonvulsant drugs, which are effective against most types of seizures. They can be used to treat absence seizures, tonic-clonic seizures, juvenile myoclonic epilepsy and complex partial seizures.

List of Fatty acid derivative anticonvulsants

View by  Brand | Generic
Drug Name Avg. Rating Reviews
Depakote (Pro)
Generic name: divalproex sodium
319 reviews
Depakote ER (Pro)
Generic name: divalproex sodium
96 reviews
Depakene (Pro)
Generic name: valproic acid
8 reviews
Generic name: valproic acid
1 review
Depakote Sprinkles (Pro)
Generic name: divalproex sodium
1 review
Depacon (Pro)
Generic name: valproic acid
No reviews
For ratings, users were asked how effective they found the medicine while considering positive/adverse effects and ease of use (1 = not effective, 10 = most effective).

See also

Medical conditions associated with fatty acid derivative anticonvulsants:

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.