Medications for Migraine
Other names: Basilar Artery Migraine; Basilar-Type Migraine; Complicated Migraine; Hemiplegic Migraine; Migraine Headache
See also: sub-topics
Drugs used to treat Migraine
The following list of medications are in some way related to or used in the treatment of this condition.
Drug name | Rating | Reviews | Activity ? | Rx/OTC | Pregnancy | CSA | Alcohol |
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sumatriptan | 7.6 | 427 reviews | Rx | ||||
Generic name: sumatriptan systemic Brand names: Imitrex, Tosymra, Imitrex Statdose, Zembrace SymTouch, Onzetra Xsail …show all Drug class: antimigraine agents For consumers: dosage, interactions, side effects For professionals: AHFS DI Monograph, Prescribing Information |
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Imitrex | 7.8 | 167 reviews | Rx | ||||
Generic name: sumatriptan systemic Drug class: antimigraine agents For consumers: dosage, interactions, side effects For professionals: Prescribing Information |
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Zomig | 7.0 | 95 reviews | Rx | ||||
Generic name: zolmitriptan systemic Drug class: antimigraine agents For consumers: dosage, interactions, side effects For professionals: Prescribing Information |
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Cambia | 7.0 | 51 reviews | Rx | ||||
Generic name: diclofenac systemic Drug class: Nonsteroidal anti-inflammatory drugs For consumers: dosage, interactions, side effects For professionals: Prescribing Information |
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Ubrelvy | 5.4 | 164 reviews | Rx | ||||
Generic name: ubrogepant systemic Drug class: CGRP inhibitors For consumers: dosage, interactions, side effects For professionals: Prescribing Information |
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Nurtec ODT | 5.1 | 149 reviews | Rx | ||||
Generic name: rimegepant systemic Drug class: CGRP inhibitors For consumers: dosage, interactions, side effects For professionals: Prescribing Information |
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Botox | 6.1 | 23 reviews | Rx | ||||
Generic name: onabotulinumtoxinA systemic Drug class: skeletal muscle relaxants For consumers: dosage, interactions, side effects For professionals: Prescribing Information |
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zolmitriptan | 7.5 | 152 reviews | Rx | ||||
Generic name: zolmitriptan systemic Brand names: Zomig, Zomig-ZMT, Zomig Nasal Spray Drug class: antimigraine agents For consumers: dosage, interactions, side effects For professionals: AHFS DI Monograph, Prescribing Information |
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rizatriptan | 8.3 | 309 reviews | Rx | ||||
Generic name: rizatriptan systemic Brand names: Maxalt, Maxalt-MLT Drug class: antimigraine agents For consumers: dosage, interactions, side effects For professionals: AHFS DI Monograph, Prescribing Information |
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Maxalt | 8.8 | 119 reviews | Rx | ||||
Generic name: rizatriptan systemic Drug class: antimigraine agents For consumers: dosage, interactions, side effects For professionals: Prescribing Information |
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Elyxyb | Rate | Add review | Rx | ||||
Generic name: celecoxib systemic Drug class: cox-2 inhibitors For consumers: dosage, interactions, side effects For professionals: Prescribing Information |
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lasmiditan | 5.2 | 16 reviews | Rx | ||||
Generic name: lasmiditan systemic Brand name: Reyvow Drug class: antimigraine agents For consumers: dosage, interactions, side effects For professionals: AHFS DI Monograph |
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onabotulinumtoxinA | 6.1 | 23 reviews | Rx | ||||
Generic name: onabotulinumtoxinA systemic Brand name: Botox Drug class: skeletal muscle relaxants For consumers: dosage, interactions, side effects For professionals: AHFS DI Monograph |
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Reyvow | 5.2 | 14 reviews | Rx | ||||
Generic name: lasmiditan systemic Drug class: antimigraine agents For consumers: dosage, interactions, side effects For professionals: Prescribing Information |
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rimegepant | 5.2 | 152 reviews | Rx | ||||
Generic name: rimegepant systemic Brand name: Nurtec ODT Drug class: CGRP inhibitors For consumers: dosage, interactions, side effects For professionals: AHFS DI Monograph |
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Tosymra | Rate | Add review | Rx | ||||
Generic name: sumatriptan systemic Drug class: antimigraine agents For consumers: dosage, interactions, side effects For professionals: Prescribing Information |
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ubrogepant | 5.4 | 164 reviews | Rx | ||||
Generic name: ubrogepant systemic Brand name: Ubrelvy Drug class: CGRP inhibitors For consumers: dosage, interactions, side effects For professionals: AHFS DI Monograph |
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gabapentin Off-label | 7.9 | 116 reviews | Rx | ||||
Generic name: gabapentin systemic Drug class: gamma-aminobutyric acid analogs For consumers: dosage, interactions, side effects For professionals: AHFS DI Monograph, Prescribing Information Off-label: Yes |
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Relpax | 8.6 | 147 reviews | Rx | ||||
Generic name: eletriptan systemic Drug class: antimigraine agents For consumers: dosage, interactions, side effects For professionals: Prescribing Information |
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Excedrin Migraine | 7.6 | 110 reviews | OTC | ||||
Generic name: acetaminophen / aspirin / caffeine systemic Drug class: analgesic combinations For consumers: dosage, interactions, side effects |
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Amerge | 8.4 | 29 reviews | Rx | ||||
Generic name: naratriptan systemic Drug class: antimigraine agents For consumers: dosage, interactions, side effects For professionals: Prescribing Information |
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cyclobenzaprine Off-label | 7.7 | 42 reviews | Rx | ||||
Generic name: cyclobenzaprine systemic Drug class: skeletal muscle relaxants For consumers: dosage, interactions, side effects For professionals: AHFS DI Monograph, Prescribing Information Off-label: Yes |
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Fiorinal | 8.5 | 48 reviews | Rx | ||||
Generic name: aspirin / butalbital / caffeine systemic Drug class: analgesic combinations For consumers: dosage, interactions, side effects For professionals: Prescribing Information |
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Treximet | 9.1 | 89 reviews | Rx | ||||
Generic name: naproxen / sumatriptan systemic Drug class: antimigraine agents For consumers: dosage, interactions, side effects For professionals: Prescribing Information |
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Maxalt-MLT | 8.7 | 71 reviews | Rx | ||||
Generic name: rizatriptan systemic Drug class: antimigraine agents For consumers: dosage, interactions, side effects For professionals: Prescribing Information |
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Frequently asked questions
- What are the side effects of the flu vaccine?
- What are the side effects of beta blockers?
- What causes optical migraines?
- How does Aimovig work to prevent migraine?
Topics under Migraine
- Chronic Migraine (2 drugs)
- Migraine Prevention (59 drugs)
Alternative treatments for Migraine
The following products are considered to be alternative treatments or natural remedies for Migraine. Their efficacy may not have been scientifically tested to the same degree as the drugs listed in the table above. However there may be historical, cultural or anecdotal evidence linking their use to the treatment of Migraine.
Learn more about Migraine
Care guides
Symptoms and treatments
Medicine.com guides (external)
Legend
Rating | For ratings, users were asked how effective they found the medicine while considering positive/adverse effects and ease of use (1 = not effective, 10 = most effective). |
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Activity | Activity is based on recent site visitor activity relative to other medications in the list. |
Rx | Prescription only. |
OTC | Over-the-counter. |
Rx/OTC | Prescription or Over-the-counter. |
Off-label | This medication may not be approved by the FDA for the treatment of this condition. |
EUA | An Emergency Use Authorization (EUA) allows the FDA to authorize unapproved medical products or unapproved uses of approved medical products to be used in a declared public health emergency when there are no adequate, approved, and available alternatives. |
Pregnancy Category | |
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A | Adequate and well-controlled studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters). |
B | Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women. |
C | Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use in pregnant women despite potential risks. |
D | There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use in pregnant women despite potential risks. |
X | Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use in pregnant women clearly outweigh potential benefits. |
N | FDA has not classified the drug. |
Controlled Substances Act (CSA) Schedule | |
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M | The drug has multiple schedules. The schedule may depend on the exact dosage form or strength of the medication. |
U | CSA Schedule is unknown. |
N | Is not subject to the Controlled Substances Act. |
1 | Has a high potential for abuse. Has no currently accepted medical use in treatment in the United States. There is a lack of accepted safety for use under medical supervision. |
2 | Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence. |
3 | Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence. |
4 | Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3. |
5 | Has a low potential for abuse relative to those in schedule 4. Has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 4. |
Alcohol | |
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X | Interacts with Alcohol. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.