Ubrelvy Side Effects

Generic name: ubrogepant

Medically reviewed by Philip Thornton, DipPharm. Last updated on May 14, 2025.

Note: This document provides detailed information about Ubrelvy Side Effects associated with ubrogepant. Some dosage forms listed on this page may not apply specifically to the brand name Ubrelvy.

Applies to ubrogepant: oral tablet.

Precautions

It is very important that your doctor check your progress at regular visits. This will allow your doctor to see if the medicine is working properly and to decide if you should continue to take it.

Do not use this medicine together with clarithromycin (Biaxin®), itraconazole (Sporanox®), or ketoconazole (Nizoral®). Using these medicines together may cause serious unwanted side effects.

Tell your doctor if you are pregnant or planning to become pregnant during treatment with this medicine.

Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal (eg, St. John's wort) or vitamin supplements.

Serious side effects of Ubrelvy

Along with its needed effects, ubrogepant (the active ingredient contained in Ubrelvy) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking ubrogepant:

Other side effects of Ubrelvy

Some side effects of ubrogepant may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

See also:

For healthcare professionals

Applies to ubrogepant: oral tablet.

General adverse events

The most commonly reported adverse reactions have included nausea and somnolence.^[Ref]

Nervous system

• Common (1% to 10%): Somnolence (includes sedation and fatigue)^[Ref]

Gastrointestinal

• Common (1% to 10%): Nausea, dry mouth^[Ref]

Frequently asked questions

• How do Ubrelvy, Qulipta and Nurtec compare for migraines?
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• Ubrelvy vs Imitrex (sumatriptan): How do they compare?
• Is Ubrelvy better than triptans?
• Is Ubrelvy a narcotic used for migraine?
• What is the mechanism of action for Ubrelvy?
• Does Ubrelvy cause rebound headaches?
• Does Ubrelvy affect the liver?
• Is Ubrelvy a triptan?

Further information

Ubrelvy side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.

Medical Disclaimer