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Is Ubrelvy a triptan?

Medically reviewed by Carmen Fookes, BPharm. Last updated on Aug 9, 2021.

Official answer

by Drugs.com

No, Ubrelvy is not a triptan, it belongs to the class of medicines known as CGRP inhibitors. CGRP stands for calcitonin gene-related peptide (CGRP) receptor antagonists (also known as gepants) and Ubrelvy works by preventing CGRP from attaching to CGRP receptors on nerve endings. CGRP is a protein that is thought to play a role in migraine attacks by causing pain, dilation of blood vessels, and inflammation. By preventing CGRP from binding to its receptor, Ubrelvy stops migraine pain and other symptoms.

Triptans, such as sumatriptan and rizatriptan, are thought to work by binding to serotonin 5‑HT1B/1D receptors, inhibiting pro-inflammatory substances and constricting cranial blood vessels. They work in a different way to CGRP inhibitors.

References

Ubrelvy Patient tips. Updated 02/2021. Drugs.com. https://www.drugs.com/tips/ubrelvy-patient-tips

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