Ubrelvy Dosage
Generic name: UBROGEPANT 50mg
Dosage form: tablet
Drug class: CGRP inhibitors
Medically reviewed by Drugs.com. Last updated on Mar 21, 2025.
2.1 Recommended Dosage
The recommended dose of UBRELVY is 50 mg or 100 mg taken orally with or without food.
If needed, a second dose may be taken at least 2 hours after the initial dose. The maximum dose in a 24-hour period is 200 mg. The safety of treating more than 8 migraines in a 30-day period has not been established.
2.2 Dosage Modifications
Dosing modifications for concomitant use of specific drugs and for patients with hepatic or renal impairment are provided in Table 1.
| Dosage Modifications |
Initial Dose |
Second Dosea (if needed) |
| Concomitant Drug | ||
| Moderate CYP3A4 Inhibitors (7.1) | 50 mg | Avoid within 24 hours |
| Weak CYP3A4 Inhibitors (7.1) | 50 mg | 50 mg |
| Strong CYP3A4 Inducers (7.2) | Avoid concomitant use | |
| Weak & Moderate CYP3A4 Inducers (7.2) | 100 mg | 100 mg |
| BCRP and/or P-gp only Inhibitors (7.3) | 50 mg | 50 mg |
| Specific Populations | ||
| Severe Hepatic Impairment (Child-Pugh Class C) (8.6) | 50 mg | 50 mg |
| Severe Renal Impairment (CLcr 15-29 mL/min) (8.7) | 50 mg | 50 mg |
| End-Stage Renal Disease (CLcr <15 mL/min) (8.7) | Avoid use | |
a Second dose may be taken at least 2 hours after the initial dose
Frequently asked questions
- How do Ubrelvy, Qulipta and Nurtec compare for migraines?
- What are the new drugs for the treatment of migraine?
- Ubrelvy vs Imitrex (sumatriptan): How do they compare?
- Is Ubrelvy better than triptans?
- Is Ubrelvy a narcotic used for migraine?
- Does Ubrelvy cause rebound headaches?
- What is the mechanism of action for Ubrelvy?
- Does Ubrelvy affect the liver?
- Is Ubrelvy a triptan?
More about Ubrelvy (ubrogepant)
- Check interactions
- Compare alternatives
- Pricing & coupons
- Reviews (268)
- Drug images
- Side effects
- Patient tips
- During pregnancy
- Support group
- FDA approval history
- Drug class: CGRP inhibitors
- Breastfeeding
- En español
Patient resources
Professional resources
Related treatment guides
See also:
Nurtec ODT
Nurtec ODT (rimegepant) is used to treat acute migraines and prevent episodic migraines, by ...
Celebrex
Celebrex is a nonsteroidal anti-inflammatory drug used to treat pain or inflammation. Learn about ...
Qulipta
Qulipta is used to help prevent episodic or chronic migraine headaches in adults. Qulipta is an ...
Botox
Botox is used for cosmetic purposes and to treat overactive bladder symptoms, urinary incontinence ...
Verapamil
Verapamil is used to treat hypertension (high blood pressure), angina (chest pain), and certain ...
Sumatriptan
Sumatriptan is a prescription medicine used to treat acute migraine headaches and cluster ...
Metoclopramide
Metoclopramide is used short-term to treat heartburn caused by gastroesophageal reflux. Learn about ...
Celecoxib
Celecoxib is a nonsteroidal anti-inflammatory drug (NSAID) used to treat pain or inflammation ...
Topiramate
Topiramate is used for bipolar disorder, borderline personality disorder, bulimia, diabetic ...
Propranolol
Propranolol is a beta-blocker that is used to treat tremors, chest pain, high blood pressure, heart ...
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
