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Ubrelvy: 7 things you should know

Medically reviewed by Carmen Pope, BPharm. Last updated on April 5, 2023.

1. How it works

2. Upsides

3. Downsides

If you are between the ages of 18 and 60, take no other medication or have no other medical conditions, side effects you are more likely to experience include:

Note: In general, seniors or children, people with certain medical conditions (such as liver or kidney problems, heart disease, diabetes, seizures) or people who take other medications are more at risk of developing a wider range of side effects. View complete list of side effects

4. Bottom Line

Ubrelvy may be used to treat acute migraine attacks in adults and works by blocking the effects of a protein, called CGRP that is thought to play a role in migraine attacks by causing pain, dilation of blood vessels, and inflammation. Ubrelvy is well-tolerated and less than 5% of people report side effects such as nausea, somnolence, and dry mouth. Ubrelvy does not prevent migraines.

5. Tips

6. Response and effectiveness

7. Interactions

Medicines that interact with Ubrelvy may either decrease its effect, affect how long it works, increase side effects, or have less of an effect when taken with Ubrelvy. An interaction between two medications does not always mean that you must stop taking one of the medications; however, sometimes it does. Speak to your doctor about how drug interactions should be managed.

Common medications that may interact with Ubrelvy include:

A second dose of Ubrelvy should not be taken by people who have consumed grapefruit or grapefruit juice or take any of these medications: verapamil, cyclosporine ciprofloxacin, fluconazole, or fluvoxamine.

Alcohol may worsen the side effects of Ubrelvy such as drowsiness, dizziness, and liver toxicity.

Avoid eating grapefruit or drinking grapefruit juice during treatment with Ubrelvy because it may increase blood levels and increase the risk of side effects such as nausea and sedation.

Note that this list is not all-inclusive and includes only common medications that may interact with Ubrelvy. You should refer to the prescribing information for Ubrelvy for a complete list of interactions.


Further information

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use Ubrelvy only for the indication prescribed.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Copyright 1996-2024 Revision date: April 4, 2023.