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Erenumab

Generic Name: erenumab (e REN ue mab)
Brand Name: Aimovig, Aimovig SureClick Autoinjector, Aimovig SureClick Autoinjector (2 pack)

Medically reviewed by Drugs.com on Apr 17, 2019 – Written by Cerner Multum

What is erenumab?

Erenumab is a monoclonal antibody that blocks the activation of a certain protein that can produce a migraine attack. This protein, called calcitonin gene- related peptide (CGRP), can cause blood vessels to dilate and cause inflammation and migraine headache pain.

Erenumab is used to prevent migraine headaches in adults.

Erenumab may also be used for purposes not listed in this medication guide.

Important Information

Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.

Before taking this medicine

You should not use erenumab if you are allergic to it.

Erenumab is not approved for use by anyone younger than 18 years old.

Tell your doctor if you have ever had:

  • an allergy to latex.

Tell your doctor if you are pregnant or plan to become pregnant. It is not known whether erenumab will harm an unborn baby. However, having migraine headaches during pregnancy may cause complications such as preeclampsia (dangerously high blood pressure that can lead to medical problems in both mother and baby). The benefit of preventing migraines may outweigh any risks to the baby.

It may not be safe to breastfeed while using erenumab. Ask your doctor about any risk.

How should I use erenumab?

Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

Erenumab is injected under the skin, usually once per month. A healthcare provider may teach you how to properly use the medication by yourself.

Read and carefully follow any Instructions for Use provided with your medicine. Ask your doctor or pharmacist if you don't understand all instructions.

Prepare your injection only when you are ready to give it. Do not use if the medicine has changed colors or has particles in it. Call your pharmacist for new medicine.

Each prefilled syringe or autoinjector is for one use only. Throw it away after one use, even if there is still medicine left inside.

Do not shake the syringe or autoinjector or you may ruin the medicine.

Your dose needs may change if you switch to a different brand, strength, or form of this medicine. Avoid medication errors by using only the form and strength your doctor prescribes.

Store erenumab in its original carton in the refrigerator, away from heat and light. Do not freeze.

Take the medicine out of the refrigerator and let it reach room temperature for 30 minutes before injecting your dose. Protect from sunlight. Do not heat the medicine in hot water or in a microwave.

You may store the medicine for up to 7 days at room temperature.

Use a needle and syringe only once and then place them in a puncture-proof "sharps" container. Follow state or local laws about how to dispose of this container. Keep it out of the reach of children and pets.

What happens if I miss a dose?

Use the medicine as soon as you remember, and then go back to your regular injection schedule. Do not use two doses at one time.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while using erenumab?

Avoid injecting erenumab into skin that is red, bruised, tender, or hard.

Erenumab side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Common side effects may include:

  • constipation; or

  • pain, swelling, or redness where the medicine was injected.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Erenumab dosing information

Usual Adult Dose for Migraine Prophylaxis:

70 mg subcutaneously once a month
-Some patients may benefit from 140 mg subcutaneously once a month

Comments:
-A dose of 140 mg should be administered as 2 consecutive subcutaneous injections of 70 mg each.

Use: For the preventative treatment of migraine.

What other drugs will affect erenumab?

Other drugs may affect erenumab, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.

Further information

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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