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User Reviews for Depakote

The following information is NOT intended to endorse drugs or recommend therapy. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners in patient care.

Learn more about Depakote.

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Condition DownUp Reviews Compare Avg. Ratings DownUp
Mania 14 reviews 15 medications
   
7.7
Epilepsy 37 reviews 41 medications
   
7.1
Bipolar Disorder 118 reviews 29 medications
   
6.2
Migraine Prevention 31 reviews 29 medications
   
5.7
Summary of Depakote reviews 200 reviews 6.6

Reviews for Depakote

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For Bipolar Disorder "Hi I've recently got married to my partner of 6 yrs, last year he was diagnosed with bipolar he has tried all different kinds of medicine but he’s started a new one call Depakote 5-10-17 for the last 2 weeks he’s had 2 personalities Mr Nice and Mr Horrible it can changed within mins do you think I should contact his doctor or bear with it. He’s never been like this I can’t talk to him, I can’t even look at him without him asking me what my problem is. This is really out of character. He is normal downer I know when they are coming and I can take time out and after 3-4 he’s back to him normal happy self but this I not sure how much more I can cope with!! We have a 5 yr old who keeps saying will daddy get better! I’m just in desperate need for some."

Life15hard (taken for less than 1 month) October 14, 2017

1 users found this comment helpful.

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For Bipolar Disorder "It made my bi polar disorder worse, I had bad ringing in my ears also my heart rate increased. But it wasn't worse then when my hallucinations got so much worse then they already are."

   
9.0

Babi Girl95 October 2, 2017

2 users found this comment helpful.

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For Bipolar Disorder "Love this medication, after 2-3 years of severe long lasting manic episodes finally decided to take meds full time. Hardly any side effects, very hungry, simply eat normally and you wont put weight on, the medication doesn't make you fat, eating does. Occasionally very tired and my stomach from time to time gets a little funny, just take with lots of water and food. Very calm, can concentrate, no racing thoughts, level, basically gave me my life back, works well at 750 even though I'm 80kgs, Dr upped me to 1000mg but felt too sedated so dropped back down. I move to 1000mg if I feel like I'm starting to drift a little for a few weeks then move back. However, this is the 7th med I have tried, all others have failed, never write one med off"

   
9.0

qwertyazsxdc (taken for 5 to 10 years) August 26, 2017

6 users found this comment helpful.

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For Epilepsy "I used to have a wonderful smart son. About 12 years ago, I noticed changes starting to take affect in his life. He was becoming agitated, he was loosing his memory, he had no energy. I was told this was due to his having so many seizures. I just this week, after having a really bad week a few weeks ago, the doctor decided to take him off of this medication in a hospital controlled setting. After one day of not taking this medication, I am starting to see the personality of my son come back. He had gotten to the point that he made terrible decisions, he was depressed often, he was confused and was loosing his memory and his ability to talk and remember words. I'm sorry, but the benefits of controlling seizures was not worth this."

   
2.0

J A J July 24, 2017

4 users found this comment helpful.

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For Migraine Prevention "Horrible! I was on it for a month, and quit immediately. I have migraine with aura. My neurologist told me a secret behind closed doors cause he was a cool dude. He said get off all the crap and once the aura comes chug two beers and it will disappear no aura no headache. He swore by it and so do I."

   
1.0

Craigsugarhill (taken for 1 to 6 months) July 14, 2017

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For Epilepsy "Have taken this med for 28+ years with no seizures during this time. I have experienced no side effects except that my hair has become very curly. Lots of compliments! No down side. I am seizure free. No other med has worked for me."

   
10

Heroncrest July 14, 2017

5 users found this comment helpful.

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For Migraine Prevention "If you want to sleep a lot, as in all day long and gain lots of weight, enjoy. I am listless, and have pre-diabetes now. "

   
3.0

depabie (taken for 1 to 2 years) May 6, 2017

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For Bipolar Disorder "Best med I've been on for Bipolar I. After 10 years on Lamictal as monotherapy, with continued mania and depression. I was hospitalized and switched to Depakote. I'm sad my doctors didn't try getting rid of the Lamictal sooner. I take 500mg (delayed-release) twice a day and, along with 80mg of Latuda, I haven't felt this stable or anxiety-free since I can remember. I'm not dulled out, back to my normal, serene self. Depakote is known to work wonders for mania, and I can attest to this effect being noticeable right away. I have gained a few pounds but I'm too happy with how calm, collected, and lucid I feel to think about letting Depakote go. No other side effects, and I don't find it highly sedating -- guess I'm one of the lucky ones."

   
10

FuckLamictal (taken for 1 to 6 months) April 15, 2017

21 users found this comment helpful.

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For Migraine Prevention "I meet with a neurologist for my migraines. He put me on depakote at bedtime. I've been on it almost 6 months now and I am starting to have them as frequent as I used to...3 times a week. I also take Keppra and duloxetine every morning. I've been struggling for almost 20 years now. I just can't get rid of one all the way. Any hospital visit that I go to, they give me benadryl and tramadol, even when I tell them it doesn't work for me. I've only gone to the hospital about 6 times in my life for them."

   
2.0

dLynR_88 (taken for 1 to 6 months) March 26, 2017

4 users found this comment helpful.

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For Bipolar Disorder "Depakote was a nightmare. Besides having acute, non-stop stomach pain with chronic diahrrea, my hair started falling out in clumps. Good thing I have thick hair or I could have been bald at the end of this drug. I don't recommend this to anyone. It was like taking poison."

   
1.0

Velveteen Rabbit (taken for 1 to 6 months) March 1, 2017

10 users found this comment helpful.

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For Migraine Prevention "Depakote was started three months ago when we exhausted all efforts with every other preventive med for migraines and headaches . I have been Experiencing these my entire life. Since 6 years old . Now 35., imitrex was used to try to knock off the migraine but insurance only provides nine pills a month so I found myself breaking them just to get through a day .And if over used they will no longer work. So I'm adding in aspirin all that junk. Ending up in ER. Just to go back the next two days because the stubborn migraine would come back , or laying in bed holding my head with ice. needless to say , on a small dose 250 a day . Wow few headaches a week I can deal with. Weight gain well now I can workout no real excuse there."

   
8.0

Ljtb123 March 1, 2017

4 users found this comment helpful.

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For Migraine Prevention "50 Year old male, 6'5" 210 lbs, I have had migraines for ten plus years. I am on 100mgs of Topamax twice a day which gave me four to five migraine a month. Doctor put me on 250mgs Depakote and so far I am down to one migraine a month with no side effects from the Depakote - that I can tell. I call that a win!"

   
9.0

VADiesel February 22, 2017

7 users found this comment helpful.

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For Bipolar Disorder "I have been through so many medications it's ridiculous... most of them didn't work AND caused severe side effects. The last one I was on before Depakote was lamotrigine (which really is better for bipolar II, from what I understand). I tend to run very manic (and don't have a thyroid anymore - cancer), so my doc and I decided this would probably be my best option. None of the new drugs worked on me. Depakote has been amazing. I can think a lot more clearly and I'm still me - just a lot more toned down. I've had no negative side effects except a slight tremor, but I'm also on xanax for severe anxiety, so its only noticeable when it's time for that. No weight gain, either. In fact, my appetite decreased. I haven't gained or lost, really."

   
10

espresso_dreams (taken for 1 to 2 years) December 27, 2016

47 users found this comment helpful.

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For Bipolar Disorder "Didn't realize how great it was till it was gone. After 4 years of failed cocktails until I found Depekote with Zoloft. I was on it for 3-5 months @1250mg and had Excessive Weight gain, insatiable hunger,,,BUT Worth it! I was productive, positive, stabilzed, making plans and following thru. Then Liver enzymes high @ 6 mo. and abruptly taken off ... Horrible move by panicked Doctor. On my third medicine since and all bad results. Any opinions on Depokote retry while protecting my liver with Milk Thistle & Turmeric? My last blood work was best its ever been. I have no faith in my Dr and am seeking a new."

   
8.0

Karyn 44ys Single Female (taken for 1 to 6 months) December 9, 2016

12 users found this comment helpful.

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For Bipolar Disorder "I take depakote 500mg extended release at night for bipolar. Mostly mania. I like depakote because it keeps me leveled. I feel normal. No mania. No depression. I do sometimes have trouble sleeping but not much. I have felt nauseous but I'm gonna go to my primary doctor because my psych says the nausea would've happened in the beginning of depakote and I've been on it for a while so probably not caused by depakote. Anyone taking depakote, make sure you go to your follow ups to check liver enzymes in your blood since it can cause liver damage. Overall I think depakote is effective for me. I tried lamictal and abilify and I hated them. They made my ankles swell up to 4 times their size. My ankles were very red and painful and swollen."

   
10

M M 555 (taken for 6 months to 1 year) December 9, 2016

23 users found this comment helpful.

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For Epilepsy "It was bad. It made me gain weight. It made me have tremors ,which will never completely go away now.I couldn't hold plates or hold cups without shaking. My head started shaking. My new Neurologist took me off of them. I was on them for over 20 yrs. I would strongly think about other meds before taking this one considering the side affect can't go away immediately or not at all ."

   
3.0

Annloss1970 November 23, 2016

8 users found this comment helpful.

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For Bipolar Disorder "My moods are better controlled. I feel more emotionally stable and physically calm. My husband has noticed a huge change in my moods and patterns."

   
8.0

Lavender pink78 November 2, 2016

34 users found this comment helpful.

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For Bipolar Disorder "this medicine works fairly well, i take the appropriate dosage, no complaints but weight gain."

   
5.0

jodubz October 8, 2016

19 users found this comment helpful.

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For Bipolar Disorder "I started depakote 3,000mg straight off when I was 15 years old I have since been taken off from it and still paying the price for it. It made me hungry constantly i gained a total of 50 pounds in 7 months I had no energy at all and no feelings no happy thoughts no sad thoughts I was literally a zombie and now I'm still seeing new doctors and switching meds all the time and I've had enough nothing is working and no one can help me I really need help and can't find it anywhere"

   
1.0

1ks October 4, 2016

31 users found this comment helpful.

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For Bipolar Disorder "I have Bipolar 1 rapid cycling and life was hell. Manic episodes were a little intense but the depression is what really killed me. It got worse and worse over time to the point I felt numb to the world. Life sucked and I wanted out. After taking many medications that didn't work (Abilify and Lithium to name a few) so I ended up in a mental hospital where they finally gave me Depakote. It literally SAVED MY LIFE!! I feel normal and stable for the first time in my life and I couldn't be happier. Im enjoying every second of my life now. God bless this drug (:"

   
10

SplashMaster6 (taken for 6 months to 1 year) September 15, 2016

77 users found this comment helpful.

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For Migraine Prevention "I had debilitating migraines for 15 years and went on a small dose of Depakote (125 mg) twenty years ago. It was amazing. Maybe five headaches over all those years. However I have now gone off hormones and having steady weight gain, increased dizziness and some depression. I am uncertain what to do. Our chemistry changes as we age, and the science is not keeping up."

   
10

Meadow kat September 4, 2016

9 users found this comment helpful.

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For Bipolar Disorder "I have major bi-polar disorder as well as severe depression and PTSD. This med (along with Seroquel and Wellbutrin) has been a literal lifesaver. For the first time in my life my moods are stable as well as manageable."

   
10

TLGeer September 1, 2016

32 users found this comment helpful.

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For Bipolar Disorder "Was on this drug for about four years with Wellbutrin. The combination worked well for the first three years; however developed severe tremors and other side effects."

   
4.0

PostmodenistCupie (taken for 2 to 5 years) August 19, 2016

19 users found this comment helpful.

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For Bipolar Disorder "Depikote was prescribed to me after 2 manic episodes. I've been on a lot of bipolar meds so many that have made me so depressed I spent a whole summer in bed. Depikote def saved my life. It's been a year now a little anxiety but not nearly as much as I've had in the past and a little weight gain and tiredness. But no mania and very little to no depression so thankyou depikote I rate u a 10 it's been a year and no mania :) ur a life saver I take 1500 mg though to so that might be y I'm so tired"

   
10

46j1592i August 18, 2016

30 users found this comment helpful.

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For Epilepsy "I have nothing good to say about this drug, zero. After doing some reading, it said that depakote normally is recommended in doses up to 1000 mg a day. I was taking 3000 mg a day for 20 years. My whole life was turned upside down by it. It affected my life in so many ways. First of all, at the dose I was taking, it had so many negative side effects, it was amazing I made it through college and graduated. The side effects at the dose I was taking were very severe. The side effects were depression, weight gain, foot drop, stuttering, tremor, and kept you in a constant haze. I had all these exponentially worse than people who take smaller doses. This was the worst drug imaginable and should be banned by the FDA."

   
1.0

Shan 22 July 21, 2016

15 users found this comment helpful.

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