User Reviews for Depakote
The following information is NOT intended to endorse drugs or recommend therapy. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners in patient care.
Learn more about Depakote.
Reviews for Depakote to treat Bipolar Disorder
"Best med I've been on for Bipolar I. After 10 years on Lamictal as monotherapy, with continued mania and depression. I was hospitalized and switched to Depakote. I'm sad my doctors didn't try getting rid of the Lamictal sooner. I take 500mg (delayed-release) twice a day and, along with 80mg of Latuda, I haven't felt this stable or anxiety-free since I can remember. I'm not dulled out, back to my normal, serene self. Depakote is known to work wonders for mania, and I can attest to this effect being noticeable right away. I have gained a few pounds but I'm too happy with how calm, collected, and lucid I feel to think about letting Depakote go. No other side effects, and I don't find it highly sedating -- guess I'm one of the lucky ones."
FuckLamictal (taken for 1 to 6 months) April 15, 2017
17 users found this comment helpful.
"Depakote was a nightmare. Besides having acute, non-stop stomach pain with chronic diahrrea, my hair started falling out in clumps. Good thing I have thick hair or I could have been bald at the end of this drug. I don't recommend this to anyone. It was like taking poison."
Velveteen Rabbit (taken for 1 to 6 months) March 1, 2017
7 users found this comment helpful.
"I have been through so many medications it's ridiculous... most of them didn't work AND caused severe side effects. The last one I was on before Depakote was lamotrigine (which really is better for bipolar II, from what I understand). I tend to run very manic (and don't have a thyroid anymore - cancer), so my doc and I decided this would probably be my best option. None of the new drugs worked on me. Depakote has been amazing. I can think a lot more clearly and I'm still me - just a lot more toned down. I've had no negative side effects except a slight tremor, but I'm also on xanax for severe anxiety, so its only noticeable when it's time for that. No weight gain, either. In fact, my appetite decreased. I haven't gained or lost, really."
espresso_dreams (taken for 1 to 2 years) December 27, 2016
38 users found this comment helpful.
"Didn't realize how great it was till it was gone. After 4 years of failed cocktails until I found Depekote with Zoloft. I was on it for 3-5 months @1250mg and had Excessive Weight gain, insatiable hunger,,,BUT Worth it! I was productive, positive, stabilzed, making plans and following thru. Then Liver enzymes high @ 6 mo. and abruptly taken off ... Horrible move by panicked Doctor. On my third medicine since and all bad results. Any opinions on Depokote retry while protecting my liver with Milk Thistle & Turmeric? My last blood work was best its ever been. I have no faith in my Dr and am seeking a new."
Karyn 44ys Single Female (taken for 1 to 6 months) December 9, 2016
11 users found this comment helpful.
"I take depakote 500mg extended release at night for bipolar. Mostly mania. I like depakote because it keeps me leveled. I feel normal. No mania. No depression. I do sometimes have trouble sleeping but not much. I have felt nauseous but I'm gonna go to my primary doctor because my psych says the nausea would've happened in the beginning of depakote and I've been on it for a while so probably not caused by depakote. Anyone taking depakote, make sure you go to your follow ups to check liver enzymes in your blood since it can cause liver damage. Overall I think depakote is effective for me. I tried lamictal and abilify and I hated them. They made my ankles swell up to 4 times their size. My ankles were very red and painful and swollen."
M M 555 (taken for 6 months to 1 year) December 9, 2016
21 users found this comment helpful.
"My moods are better controlled. I feel more emotionally stable and physically calm. My husband has noticed a huge change in my moods and patterns."
Lavender pink78 November 2, 2016
29 users found this comment helpful.
"this medicine works fairly well, i take the appropriate dosage, no complaints but weight gain."
jodubz October 8, 2016
18 users found this comment helpful.
"I started depakote 3,000mg straight off when I was 15 years old I have since been taken off from it and still paying the price for it. It made me hungry constantly i gained a total of 50 pounds in 7 months I had no energy at all and no feelings no happy thoughts no sad thoughts I was literally a zombie and now I'm still seeing new doctors and switching meds all the time and I've had enough nothing is working and no one can help me I really need help and can't find it anywhere"
1ks October 4, 2016
30 users found this comment helpful.
"I have Bipolar 1 rapid cycling and life was hell. Manic episodes were a little intense but the depression is what really killed me. It got worse and worse over time to the point I felt numb to the world. Life sucked and I wanted out. After taking many medications that didn't work (Abilify and Lithium to name a few) so I ended up in a mental hospital where they finally gave me Depakote. It literally SAVED MY LIFE!! I feel normal and stable for the first time in my life and I couldn't be happier. Im enjoying every second of my life now. God bless this drug (:"
SplashMaster6 (taken for 6 months to 1 year) September 15, 2016
73 users found this comment helpful.
"I have major bi-polar disorder as well as severe depression and PTSD. This med (along with Seroquel and Wellbutrin) has been a literal lifesaver. For the first time in my life my moods are stable as well as manageable."
TLGeer September 1, 2016
28 users found this comment helpful.
"Was on this drug for about four years with Wellbutrin. The combination worked well for the first three years; however developed severe tremors and other side effects."
PostmodenistCupie (taken for 2 to 5 years) August 19, 2016
16 users found this comment helpful.
"Depikote was prescribed to me after 2 manic episodes. I've been on a lot of bipolar meds so many that have made me so depressed I spent a whole summer in bed. Depikote def saved my life. It's been a year now a little anxiety but not nearly as much as I've had in the past and a little weight gain and tiredness. But no mania and very little to no depression so thankyou depikote I rate u a 10 it's been a year and no mania :) ur a life saver I take 1500 mg though to so that might be y I'm so tired"
46j1592i August 18, 2016
26 users found this comment helpful.
"2007 - Put on 750 mg/day of Depakote alongside Lithium 800 mg/day. Killed libido stone dead. Did not help stabilise mood but worked away destabilising good lithium effect. Found this out after stopping Depakote 2014. Depakote has caused prostate cancer which was removed by radical prostatectomy June 2014. So it has caused me to be severely incontinent now, with erectile dysfunction. This month June 2016 it has been confirmed I have Multiple Myeloma a blood cancer. Depakote is the suspected trigger again. These effects result from being put on Depakote for seven years with no investigation of physical symptoms being reported to "psychiatric professionals""
Sion (taken for 5 to 10 years) July 12, 2016
25 users found this comment helpful.
"I took my first dose of Depakote at night before bed. The next day I was so leveled out; I wasn't talking fast it was great. The rest of the day starting around 1:00 p.m. I slept all day. I woke up at 12:00 a.m. with my eyes extremely wide and dilated, my skin on my arms and legs was swirling (like the Starry Night painting), the walls were moving and things on the wall were levitating up and down. I was up until 3:00 a.m. and an on call nurse told me to sleep so it would wear off; I have never taken this medication again. (Taken for Schizoaffective Disorder, Bipolar type)"
TamaraAngel (taken for less than 1 month) July 11, 2016
22 users found this comment helpful.
"Depakote put about 60 pounds on me. It did nothing for my mood accept make me a zombie. I sat around and did nothing. I had no energy, my skin itched non-stop, I developed migraine headaches and felt plain shitty all over. My muscles ached, stomach/abdomen hurt. I complained about it and my doctor upped the dose and I was on 2000 mg xr when I could not stand it any longer. I took myself off of it and have changed doctors. I hope this one will listen to what I say."
info2pondergmail.com (taken for 1 to 2 years) June 22, 2016
31 users found this comment helpful.
"Noticed that depakote improved stability of mood and reduced depression. However, it did not help with mania mood swings. This drug also totally removed my libido. I have never experienced such an inability for sexual activity than while taking this drug. A week after stopping the drug and sexual libido is back. I would avoid this drug if male."
Manuel231 May 15, 2016
28 users found this comment helpful.
"Really intense side effects. Weight gain, zombie like behavior, etc."
rxqp89 (taken for 1 to 6 months) April 22, 2016
29 users found this comment helpful.
"I took Depakote 500mg for a week then increased my dose to 1000mg after the next week. The next day I began having terrible stomach pains and pains in my kidneys, especially after eating. I emailed my doctor and he told me the side effects would subside but they didn't. They actually got worse and the abdominal pain would linger all day and night. I also had a hard time sleeping, I would wake up every 1-2 hours and sleep less than 6 hours a night, along with having very vivid dreams. The dreams later got more and more violent/terrifying and I began to fall into a very deep depression, one I had never felt in my entire life. I stopped taking this medication after three weeks. I will never take this medication even if it saved my life."
Bipolar2 April 2, 2016
43 users found this comment helpful.
"Diagnosed 6 years ago as Bipolar 2 after 20 years of being all over the place. crazy ups/back downs but only ever treated for depression, I was put on a variety of medications in the first year that made me so ill, weight gains/losses, irrational thoughts/ideas, constantly felt ill with colds/flu had to keep changing medications and doses to see if they would work, then given Depakote, wow I felt human again within 2 weeks, settled, calm, clear head no side effects, its done wonders for me that no other got close to, I have my life back"
Ekomoon (taken for 2 to 5 years) February 20, 2016
82 users found this comment helpful.
"I am not very fond of Depakote. When I took it it didn't improve my moodswings that much. In the beginning it made me nauseous & caused my hair to fall out. No, I didn't go bald, but it thinned out my hair enough that my hairstylist noticed. Eventually, my hair stopped falling out, but I gained a lot of weight & I had very bad tremors & bad coordination. If you do decide to take this medicine make sure your doctor tests your blood regularly. I think you are supposed to have your blood tested every 6 months."
~*Melanie*~ (taken for 6 months to 1 year) February 2, 2016
33 users found this comment helpful.
"I have been on depakote for about six months for bipolar II after being taken off lithium, I am feeling more like myself but still feel a slight emptiness and falseness, I am also taking lamotrigene and pregablin for extreme anxiety. I have put on nearly a stone in six months, I am also being tested for ADHD, I am 48 yrs old and have had this from when I was a child, when you have grown up with this you do not know any different until you become very ill, sorry for the rambling not sure if it makes sense. x"
amsay January 15, 2016
63 users found this comment helpful.
"I am honestly the happiest person ever since my Psychiatrist prescribed Depakote for me, NO MORE RAPID CYCLING!! I take two 500mg tablets about 20 minutes minutes before bed and I sleep throughout only waking up when my back aching in pain; I'll save that for my Baclofen and Prednisone post. I do not experience the manic highs as I was once did; however I still have my low days but everyone does! My low days are no where near the days when I on Trileptal or any SSRIs. I was taking Ability and Lithium for a week (this is my experience) I started seeing the world in two-dimensions, sort of like the early Nintendo characters. I freaking out!! That was it. Make sure to get blood tests every months to ensure your Depakote are in line. A "
dsran87 (taken for 2 to 5 years) December 23, 2015
56 users found this comment helpful.
"Best medicine I've been on !!!! Focused,low anxiety,sleeping well no night terrors ."
Happyintexas (taken for 1 to 6 months) December 11, 2015
49 users found this comment helpful.
"My doc switched me from Prozac & Abilify to Depakote ER 500mg at bed time. I've been taking Depakote ER 500mg for almost 4 months now. Everyone in my life has noticed a positive change in me. I feel so calm within. My anxiety & insomnia are very much under control now. I'vw suffeerd with bipolar since my teens. I am 38yrs old. Depakote ER 500 has saved my life! I was done with psych meds & ready to just give up! I'm so glad I have such an amazing doc. No more changing my meds. Depakote ER 500mg in combo with Xanax 1mg 3x's per day has me back to feeling like myself again. Also, I don't need to take the xanax everyday or 3x's per day anymore. The Depakote ER 500mg works for numerous disorders I suffer from. I could go on about the pro's of this med."
Surviver (taken for 1 to 6 months) December 9, 2015
88 users found this comment helpful.
"I was recently diagnosed with Bipolar II. This medication has been a life saver (literally) for me. It has helped keep my emotions in check. I took another medication lamicital that caused one continuous headache that never went away. My psychiatrist started me on a low dose of that medication so I wouldn't get a deadly rash. My emotions were all over the place and I was miserable. My psychiatrist put me on Depakote. At first this medication made me sluggish and hungry. I gained 5 lbs in the first 2 weeks. Since then I have laid off the snacks and beverages and have since gotten adjusted to the meds (also taking Zoloft). Three pounds have come off without trying. Each person is different, but this has really worked for me."
clemsontigergrl (taken for less than 1 month) December 8, 2015
49 users found this comment helpful.
More about Depakote (divalproex sodium)
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- Drug class: fatty acid derivative anticonvulsants