Depakote Alternatives Compared
| Depakote Remove Depakote from your drug comparison | Lamictal Remove Lamictal from your drug comparison | Lamotrigine Remove Lamotrigine from your drug comparison |
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| Depakote divalproex sodium Remove Depakote from your drug comparison | Lamictal lamotrigine Remove Lamictal from your drug comparison | Lamotrigine Remove Lamotrigine from your drug comparison | ||||||||||||||||||||||||
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Depakote may be used in the treatment of epilepsy, mania, and to prevent migraines; however, people taking Depakote should be monitored for potentially fatal side effects such as liver failure and... View more |
Lamictal is used to decrease the frequency and severity of seizures in some types of epilepsy and also to stabilize mood in bipolar disorder. Rarely, Lamictal may cause a potentially fatal rash... View more |
Lamotrigine may be used to decrease the frequency and severity of seizures in some types of epilepsy and also to stabilize mood in bipolar disorder. Rarely, lamotrigine may cause a potentially fatal... View more |
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Prescription only |
Prescription only |
Prescription only |
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Ratings & Reviews |
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Drug Class |
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Side Effects |
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Common side effects include: abdominal pain, asthenia, dizziness, drowsiness, nausea, anorexia. See the full Depakote side effects document. |
Common side effects include: ataxia, skin rash, headache, insomnia, nausea. See the full Lamictal side effects document. |
Commonly reported side effects include: ataxia, skin rash, headache, insomnia, nausea. See the full lamotrigine side effects document. |
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Pricing and Coupons* Prices are without insurance |
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View all Depakote prices and generic prices |
View all Lamictal prices and generic prices |
View all lamotrigine prices |
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Generic Availability |
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Yes (this medicine) |
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Dosage Form(s) Available |
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Brand Names |
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| Other divalproex sodium brands include: Depakote ER, Depakote Sprinkles | Other lamotrigine brands include: Lamictal CD, Lamictal ODT, Lamictal XR, Subvenite | Lamictal, Lamictal CD, Lamictal ODT, Lamictal XR, Subvenite | ||||||||||||||||||||||||
Half LifeThe half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. |
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16 hours |
25.7 hours |
25.7 hours |
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CSA Schedule**View glossary of terms. |
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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Pregnancy Category |
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Category D
Positive evidence of risk
When Treating Epilepsy And Manic Episodes Associated With Bipolar Disorder
Category X
Not for use in pregnancy
When Treating Migraine See the full Pregnancy Warnings document. |
Category C
Risk cannot be ruled out
See the full Pregnancy Warnings document. |
Category C
Risk cannot be ruled out
See the full Pregnancy Warnings document. |
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Drug Interactions |
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A total of 361 drugs are known to interact with Depakote:
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A total of 265 drugs are known to interact with Lamictal:
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A total of 265 drugs are known to interact with lamotrigine:
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Alcohol/Food/Lifestyle Interactions |
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Disease Interactions |
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First Approval Date |
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March 10, 1983 |
December 27, 1994 |
December 27, 1994 |
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WADA ClassView World Anti-Doping Agency classifications. |
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N/A |
N/A |
N/A |
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More Information |
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Consumer Resources |
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Professional Resources |
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Related Treatment Guide |
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** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.