Depakote Alternatives Compared
| Depakote | Nurtec ODT | OnabotulinumtoxinA |
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| Depakote (divalproex sodium) | Nurtec ODT (rimegepant) | OnabotulinumtoxinA |
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Prescription only
Depakote may be used in the treatment of epilepsy, mania, and to prevent migraines; however, people taking Depakote should be monitored for potentially fatal side effects such as liver failure and... View more |
Prescription only
Nurtec ODT may be placed onto or under the tongue to treat the symptoms of migraine in adults, and it may also be used to prevent episodic migraine when taken every second day. Nurtec ODT works by... View more |
Prescription only
Prescribed for Glabellar Lines, Cervical Dystonia, Chronic Migraine, Chronic Spasticity, Crow's Feet, Orbicularis Oculi, Facial Wrinkles, Blepharospasm, Dystonia, Hyperhidrosis, Lower Limb... View more |
Related suggestions Migraine Prevention (Migraine Prophylaxis)
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| More about Depakote (divalproex sodium) | More about Nurtec ODT (rimegepant) | More about OnabotulinumtoxinA | ||||||||||||||||
| Generic Status | ||||||||||||||||||
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No lower-cost generic available |
No lower-cost generic available |
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| Ratings & Reviews | ||||||||||||||||||
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Depakote has an average rating of 6.2 out of 10 from a total of 317 ratings on Drugs.com. 48% of reviewers reported a positive effect, while 29% reported a negative effect. |
Nurtec ODT has an average rating of 5.3 out of 10 from a total of 201 ratings on Drugs.com. 41% of reviewers reported a positive effect, while 43% reported a negative effect. |
OnabotulinumtoxinA has an average rating of 5.5 out of 10 from a total of 458 ratings on Drugs.com. 45% of reviewers reported a positive effect, while 43% reported a negative effect. |
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| Drug Class | ||||||||||||||||||
| Side Effects | ||||||||||||||||||
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Common side effects include:
See also: Depakote side effects in more detail. |
See also: Nurtec ODT side effects in more detail. |
Commonly reported side effects include:
See also: onabotulinumtoxinA side effects in more detail. |
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| Pricing and Coupons * Prices are without insurance | ||||||||||||||||||
View all Depakote prices and generic prices |
View all Nurtec ODT prices |
We could not find an exact match for this medicine. Try searching the Price Guide directly. |
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| Dosage Form(s) Available | ||||||||||||||||||
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N/A |
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| Brand Names | ||||||||||||||||||
| Other divalproex sodium brands include: Depakote ER, Depakote Sprinkles |
N/A |
Botox, Botox Cosmetic | ||||||||||||||||
| Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | ||||||||||||||||||
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16 hours |
11 hours |
N/A |
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| CSA Schedule ** View glossary of terms | ||||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | ||||||||||||||||||
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Category D
Positive evidence of risk
When Treating Epilepsy And Manic Episodes Associated With Bipolar Disorder
Category X
Not for use in pregnancy
When Treating Migraine See the full pregnancy warnings document. |
Summary unavailable. See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | ||||||||||||||||||
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A total of 377 drugs are known to interact with Depakote:
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A total of 141 drugs are known to interact with Nurtec ODT:
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A total of 114 drugs are known to interact with onabotulinumtoxinA:
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| Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | ||||||||||||||||||
| First Approval Date | ||||||||||||||||||
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March 10, 1983 |
February 27, 2020 |
N/A |
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| WADA Class View World Anti-Doping Agency classifications. | ||||||||||||||||||
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N/A |
N/A |
N/A |
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| More Information | ||||||||||||||||||
| Patient resources | ||||||||||||||||||
| Professional Resources | ||||||||||||||||||
| Related Treatment Guide | ||||||||||||||||||
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** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.