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Cariprazine use while Breastfeeding

Drugs containing Cariprazine: Vraylar

Medically reviewed by Drugs.com. Last updated on March 28, 2021.

Cariprazine Levels and Effects while Breastfeeding

Summary of Use during Lactation

No information is available on the use of cariprazine during breastfeeding. Until more data become available, an alternate drug may be preferred, especially while nursing a newborn or preterm infant.

Drug Levels

Cariprazine is metabolized to two major active metabolites with a half-life of 2 to 4 days. Desmethylcariprazine has a half-life of 1 to 2 days, and didesmethylcariprazine has a half-life of 1 to 3 weeks. Both are considered to be equipotent to cariprazine. The drug and metabolites are all >90% bound to plasma proteins.

Maternal Levels. Relevant published information was not found as of the revision date.

Infant Levels. Relevant published information was not found as of the revision date.

Effects in Breastfed Infants

Relevant published information was not found as of the revision date.

Effects on Lactation and Breastmilk

Relevant published information was not found as of the revision date. Cariprazine has little to no effect on serum prolactin levels.

Alternate Drugs to Consider

Haloperidol, Olanzapine, Quetiapine, Risperidone

Substance Identification

Substance Name

Cariprazine

CAS Registry Number

839712-12-8

Drug Class

  • Breast Feeding
  • Lactation
  • Antipsychotic Agents

Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.