Depakote (divalproex sodium) Drug Interactions
A total of 752 drugs (5375 brand and generic names) are known to interact with Depakote (divalproex sodium).
- 22 major drug interactions (67 brand and generic names)
- 679 moderate drug interactions (4955 brand and generic names)
- 51 minor drug interactions (353 brand and generic names)
Check for interactions with Depakote (divalproex sodium)
Common medications checked in combination with Depakote (divalproex sodium)
- Abilify (aripiprazole)
- Adderall (amphetamine / dextroamphetamine)
- Ambien (zolpidem)
- Ativan (lorazepam)
- Benadryl (diphenhydramine)
- clonazepam
- Cymbalta (duloxetine)
- Fioricet (acetaminophen / butalbital / caffeine)
- gabapentin
- hydrocodone
- ibuprofen
- Klonopin (clonazepam)
- Lamictal (lamotrigine)
- levothyroxine
- Lexapro (escitalopram)
- lisinopril
- lithium
- melatonin
- metformin
- Mucinex (guaifenesin)
- naproxen
- omeprazole
- Prozac (fluoxetine)
- Risperdal (risperidone)
- Seroquel (quetiapine)
- Topamax (topiramate)
- trazodone
- Tylenol (acetaminophen)
- valproic acid
- Vitamin D3 (cholecalciferol)
- Xanax (alprazolam)
- Zoloft (sertraline)
Depakote (divalproex sodium) alcohol/food Interactions
There is 1 alcohol/food interaction with Depakote (divalproex sodium)
Depakote (divalproex sodium) disease Interactions
There are 8 disease interactions with Depakote (divalproex sodium) which include:
- Depression
- Liver Disease
- Urea Cycle Disorders
- Suicidal Tendency
- Hiv/Cmv
- Thrombocytopenia
- Thyroid Function Tests
- Urine Ketone Test
See Also
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No information available. |
Do not stop taking any medications without consulting your healthcare provider.
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