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Medications for Mania

Other names: Hypomania; Manic Disorder

Bipolar affective disorder is a mood disorder characterized by mood swings from mania (exaggerated feeling of well-being, stimulation, and grandiosity in which a person can lose touch with reality) to depression (overwhelming feelings of sadness, anxiety, and low self-worth, which can include suicidal thoughts and suicide attempts).

Drugs used to treat Mania

The medications listed below are related to or used in the treatment of this condition.

Drug name Rating Reviews Activity ? Rx/OTC Pregnancy CSA Alcohol
Depakote 7.0 24 reviews for Depakote to treat Mania Rx D N X
Generic name:
divalproex sodium systemic
Drug class:
fatty acid derivative anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
divalproex sodium 7.4 35 reviews for divalproex sodium to treat Mania Rx D N X
Generic name:
divalproex sodium systemic
Brand names:
Depakote, Depakote ER
Drug class:
fatty acid derivative anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
lithium 8.3 19 reviews for lithium to treat Mania Rx D N X
Generic name:
lithium systemic
Brand name:
Lithobid
Drug class:
antimanic agents
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Risperdal 7.1 8 reviews for Risperdal to treat Mania Rx C N X
Generic name:
risperidone systemic
Drug class:
atypical antipsychotics
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Depakote ER 8.0 3 reviews for Depakote ER to treat Mania Rx D N X
Generic name:
divalproex sodium systemic
Drug class:
fatty acid derivative anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Haldol 2.9 11 reviews for Haldol to treat Mania Rx C N X
Generic name:
haloperidol systemic
Drug class:
miscellaneous antipsychotic agents
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
haloperidol 3.2 20 reviews for haloperidol to treat Mania Rx C N X
Generic name:
haloperidol systemic
Brand names:
Haldol, Haldol Decanoate
Drug class:
miscellaneous antipsychotic agents
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
risperidone 6.5 14 reviews for risperidone to treat Mania Rx C N X
Generic name:
risperidone systemic
Brand name:
Risperdal
Drug class:
atypical antipsychotics
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
valproic acid Off-label 10 2 reviews for valproic acid to treat Mania Rx D N X
Generic name:
valproic acid systemic
Drug class:
fatty acid derivative anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Off-label:
Yes
chlorpromazine 6.7 7 reviews for chlorpromazine to treat Mania Rx N N X
Generic name:
chlorpromazine systemic
Drug class:
phenothiazine antiemetics, phenothiazine antipsychotics
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
allopurinol Off-label Rate Add review Rx C N X
Generic name:
allopurinol systemic
Drug class:
antigout agents, antihyperuricemic agents
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Off-label:
Yes
Lithobid Rate Add review Rx D N X
Generic name:
lithium systemic
Drug class:
antimanic agents
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Haldol Decanoate Rate Add review Rx C N X
Generic name:
haloperidol systemic
Drug class:
miscellaneous antipsychotic agents
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information

Frequently asked questions

View more FAQ

Learn more about Mania

Care guides

Medicine.com guides (external)

Legend

Rating For ratings, users were asked how effective they found the medicine while considering positive/adverse effects and ease of use (1 = not effective, 10 = most effective).
Activity Activity is based on recent site visitor activity relative to other medications in the list.
Rx Prescription only.
OTC Over-the-counter.
Rx/OTC Prescription or Over-the-counter.
Off-label This medication may not be approved by the FDA for the treatment of this condition.
EUA An Emergency Use Authorization (EUA) allows the FDA to authorize unapproved medical products or unapproved uses of approved medical products to be used in a declared public health emergency when there are no adequate, approved, and available alternatives.
Expanded Access Expanded Access is a potential pathway for a patient with a serious or immediately life-threatening disease or condition to gain access to an investigational medical product (drug, biologic, or medical device) for treatment outside of clinical trials when no comparable or satisfactory alternative therapy options are available.
Pregnancy Category
A Adequate and well-controlled studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).
B Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
C Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
D There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
X Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use in pregnant women clearly outweigh potential benefits.
N FDA has not classified the drug.
Controlled Substances Act (CSA) Schedule
M The drug has multiple schedules. The schedule may depend on the exact dosage form or strength of the medication.
U CSA Schedule is unknown.
N Is not subject to the Controlled Substances Act.
1 Has a high potential for abuse. Has no currently accepted medical use in treatment in the United States. There is a lack of accepted safety for use under medical supervision.
2 Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence.
3 Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence.
4 Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3.
5 Has a low potential for abuse relative to those in schedule 4. Has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 4.
Alcohol
X Interacts with Alcohol.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.